A5028341023- Sepsis Diagnosis and Treatment
- Bacterial Identification and Susceptibility Testing
- COVID-19 Clinical Research Studies
- Antibiotic Use and Resistance
- Streptococcal Infections and Treatments
- Infective Endocarditis Diagnosis and Management
- Nosocomial Infections in ICU
- Dialysis and Renal Disease Management
- Health Systems, Economic Evaluations, Quality of Life
- Antimicrobial Resistance in Staphylococcus
- Thermal Regulation in Medicine
- Central Venous Catheters and Hemodialysis
- Climate Change and Health Impacts
- Long-Term Effects of COVID-19
- Infectious Diseases and Tuberculosis
- Pancreatitis Pathology and Treatment
- Pneumonia and Respiratory Infections
- Iron Metabolism and Disorders
- SARS-CoV-2 and COVID-19 Research
- Vitamin C and Antioxidants Research
- Cardiac Arrest and Resuscitation
- Intensive Care Unit Cognitive Disorders
- Dermatological and COVID-19 studies
- Meta-analysis and systematic reviews
- SARS-CoV-2 detection and testing
Osaka University
2022-2025
Osaka University Hospital
2022-2025
Osaka City University
2025
Kyoto University
2015-2024
Kyoto City Hospital
2011-2023
Hyogo Prefectural Amagasaki General Medical Center
2023
Kyoto University of Education
2017-2021
Japanese Red Cross Medical Center
2021
Kyoto University Hospital
2017-2018
Institute for Health Economics and Policy
2018
Although hypervirulent Klebsiella pneumoniae (hvKp) has been associated with severe community-acquired infections that occur among relatively healthy individuals, information about hvKp in health care settings remains limited. Here, we systematically analyzed the clinical and molecular characteristics of K. isolates causing bloodstream a cross-sectional study. Clinical from hospitals across Japan were by review medical records. Whole-genome sequencing causative was performed. Bacterial...
Abstract The geriatric nutritional risk index (GNRI) and creatinine (Cr) are indexes often used as surrogates in patients receiving hemodialysis. However, few studies have directly compared the clinical characteristics of these two indexes. We investigated 3,536 hemodialysis enrolled Japan DOPPS phases 4 5. primary outcome was all-cause mortality main exposures were GNRI Cr index. confirmed association between estimated by a multivariable-adjusted Cox proportional hazards model. During...
<b><i>Background:</i></b> Despite improvements in dialysis treatment, mortality rates remain high, especially among older hemodialysis patients. Quality of life (QOL) patients is strongly associated with higher risk death. This study aimed to describe the health-related QOL and its change maintenance demonstrate characteristics QOL. <b><i>Methods:</i></b> Data on 892 aged 60 years or who were surveyed using Kidney Disease Life Short Form at...
Abstract Background Recent database studies indicate an increase in new cases of autoimmune inflammatory rheumatic diseases (AIIRDs) following coronavirus disease 2019 (COVID-19), but these have significant limitations. The main issue is the reliance on codes like ICD-10 for diagnoses, which does not ensure accuracy. Overcoming limitation previous studies, we studied whether a history COVID-19 infection increases risk developing AIIRDs requiring disease-specific treatment.Figure 1.Details...
Abstract Background Current guidelines for community-acquired pneumonia (CAP) include ampicillin/sulbactam as an initial treatment option, though they do not mandate routine coverage of anaerobic organisms. This study aimed to compare the effectiveness with that ceftriaxone CAP in older adults. Methods was conducted using target trial emulation framework, utilizing a nationwide Japanese database (May 2010–June 2023). The included patients aged 65 years and older, admitted Diagnosis Procedure...
Hypothermia is a risk factor for death in intensive care unit (ICU) patients with severe sepsis and septic shock. In the present study, we investigated association between body temperature (BT) on arrival at emergency department (ED) mortality bacterial infection. We conducted retrospective cohort study consecutive ED over 15 years of age infection who were admitted to an urban teaching hospital Japan 2010 2012. The main outcome measure was 30-day in-hospital mortality. Each patient assigned...
Background: The infectious diseases (ID) consultation service is a new clinical entity in Japan. We examined the impact of ID on diagnosis infective endocarditis (IE) at large teaching hospital Methods: Routine with an for cases positive blood culture was implemented Kameda Medical Center November 2004. In addition, doctors started to give lectures and also provided local guidelines ID. compared incidence IE during 3-y 10-month period before intervention that 5-y 2-month after intervention....
The prognostic utility of serum C reactive protein (CRP) alone in sepsis is controversial. We used decision curve analysis (DCA) to evaluate the clinical usefulness combining CRP levels with CUBR-65 score patients suspected sepsis.Retrospective cohort study.Emergency department (ED) an urban teaching hospital Japan.Consecutive ED over 15 years age who were admitted after having a blood culture taken between 1 January 2010 and 31 December 2012.30-day in-hospital mortality.Data from 1262...
Accidental hypothermia is a serious condition that requires immediate and accurate assessment to determine severity treatment. Currently, accidental evaluated using the Swiss grading system which uses core body temperature clinical findings; however, research has shown not associated with in-hospital mortality in urban settings. Therefore, we developed validated scale for predicting among Japanese patients hypothermia.Data this multi-center retrospective cohort study were obtained from...
Previous studies have suggested that peripheral venous catheter is a significant source of gram-negative bacteraemia in patients with malignancy. We aimed to identify risk factors and develop clinical prediction rule for the involvement organisms catheter-associated bloodstream infections (PVC-BSIs) among malignancy.This retrospective cohort study was conducted at 700-bed cancer hospital Japan. Consecutive diagnosed PVC-BSI based on microbiological criteria were included this study. Based...
A domestic case of rabies has not been reported in Japan since 1957. The last was an imported from Nepal 1970. We recently experienced a new the Philippines, first 36 years. Although Japanese people are about to forget dangers rabies, this should serve as warning those who planning trip abroad.
In 2017, the Japanese government published an evidence-based manual describing appropriate use of antibiotics in outpatient settings to tackle problem antimicrobial resistance. To fill evidence-practice gap, we developed a clinician-targeted course aimed at improving clinician skills daily clinical practice treating acute respiratory tract infections (RTIs) based on manual. The aim this study was evaluate efficacy course.This consisted lectures using illness scripts and checklists, as well...
Abstract Background Recent randomized clinical trials suggest that the effect of using cetylpyridinium chloride (CPC) mouthwashes on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral load in COVID-19 patients has been inconsistent. Additionally, no study investigated effectiveness on-demand aqueous chlorine dioxide mouthwash against COVID-19. Methods We performed a randomized, placebo-controlled, open-label trial to assess for any effects salivary SARS-CoV-2 among...
It is challenging for clinicians to determine the cause of occurrence fever in COVID-19 patients after corticosteroid discontinuation. Blood cultures help us distinguish between secondary infections and rebound phenomena. We report a case non-typhoidal Salmonella bacteremia 34-year-old male patient who developed discontinuing corticosteroids.