A5027283105- Kawasaki Disease and Coronary Complications
- Cardiac Arrest and Resuscitation
- Coronary Artery Anomalies
- Thermal Regulation in Medicine
- Cardiac Imaging and Diagnostics
- Cardiovascular Issues in Pregnancy
- Climate Change and Health Impacts
- Liver Disease Diagnosis and Treatment
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Vasculitis and related conditions
- Fermentation and Sensory Analysis
- Hepatitis B Virus Studies
- Toxic Organic Pollutants Impact
- Hepatitis C virus research
- Coronary Interventions and Diagnostics
- Hepatitis Viruses Studies and Epidemiology
- Food Quality and Safety Studies
- Mechanical Circulatory Support Devices
- Microbial Metabolic Engineering and Bioproduction
- Inflammasome and immune disorders
- Cardiac Valve Diseases and Treatments
- Effects and risks of endocrine disrupting chemicals
- Advanced MRI Techniques and Applications
- Cardiovascular Disease and Adiposity
Kyoto Prefectural University of Medicine
2014-2025
Nippon Medical School
2013-2024
Nippon Medical School Hospital
2013-2022
National Cerebral and Cardiovascular Center
2009-2021
North Medical Center
2019-2020
Tohoku University
1998-2018
Kanazawa Medical University
2014-2016
Nara Medical University
2015
Nara City Hospital
2010-2013
Chiba Hokusou Hospital
2009
Few studies with sufficient statistical power have shown the association of z score coronary arterial internal diameter events (CE) in patients Kawasaki disease (KD) artery aneurysms (CAA).To clarify time-dependent CE occurrence KD CAA.This multicenter, collaborative retrospective cohort study 44 participating institutions included 1006 younger than 19 years who received a angiography between 1992 and 2011.The CE, including thrombosis, stenosis, obstruction, acute ischemic events,...
Abstract Background and Aims: Nocturnal gastric acid breakthrough (NAB) is defined as an intragastric pH < 4.0 lasting more than 1 h during the night in patients taking a proton pump inhibitor (PPI). Gastroesophageal reflux disease (GERD) with nocturnal gastroesophageal accompanied by NAB are thought to be refractory PPI treatment. The aim of this study was endoscopically identify predominant reflux. Methods: subjects were 37 erosive esophagitis (Los Angeles classification (LA) grade A,...
Background Coronary arterial aneurysms (CAAs) associated with Kawasaki disease (KD) significantly affect prognosis. However, the clinical course of CAAs and factors CAA regression have not been well analyzed. Methods Results The cohort Z-Score 2nd Project Stage study, a multicenter, retrospective, study involving 44 institutions in Japan including 1006 patients KD, was examined. were classified by z score their internal diameter acute phase: small (z<5), medium (5≤z<10), large (z≥10). lower...
Targeted temperature management (TTM) is considered a beneficial treatment for improving outcomes in patients with OHCA due to acute coronary syndrome (ACS). The comparative benefits of hypothermic TTM (32–34°C) versus normothermic (35–36°C) are unclear. This study compares these strategies neurological and survival rates ACS. We conducted retrospective analysis using data from the Japanese Association Acute Medicine Out-of-Hospital Cardiac Arrest (JAAM-OHCA) registry, encompassing 68,110...
Despite growing evidence supporting the efficacy of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for accidental hypothermia (AH), few studies have assessed its real-world application. We aimed to describe use and outcomes VA-ECMO in AH patients using data from a multicenter registry. This retrospective study included adult Japanese network registry (J-Point registry) between April 2011 March 2016. analyzed patient characteristics, in-hospital data, indications, clinical those...
Abstract Background : Although some laboratory findings are known to be indicators of the risk giant coronary aneurysm formation among Kawasaki disease patients, an appropriate cut‐off point predict is not clear. Methods One hundred and five patients with aneurysms were selected from 15th 16th nationwide surveys in Japan. A total 2936 without recruited a single hospital as control group. Odds ratios calculated for six data specific values points. Receiver operating characteristic (ROC)...
Background Accidental hypothermia (AH) has higher incidence and mortality in geriatric populations. Japan a rapidly ageing population, little is known about the epidemiology of this country. Methods We created an AH registry based on retrospective review patients visiting ED 12 institutions with temperature ≤35°C between April 2011 March 2016. The severity was classified as mild (≤35, ≥32°C), moderate (<32, ≥28°C) or severe (<28°C). relationship in-hospital assessed using multivariable...
The long-term prognosis of those having a history Kawasaki disease (KD) is still unknown.Between July 1982 and December 1992, 52 collaborating hospitals collected data on all patients new definite diagnosis KD. Patients were followed-up until 31, 2004 or their death. Standardized mortality ratios (SMRs) calculated based the Japanese vital statistics data. Of 6,576 enrolled, 36 (27 males, 9 females) died SMR was 1.14. Despite high SMRs during acute phase, rate not after phase for entire group...
Mosapride citrate (mosapride) is a serotonin 5-hydroxytryptamine 4 receptor agonist known to promote gastric emptying and large-intestine motility. We assessed the effect of mosapride on postoperative ileus following colon surgery.Forty patients with cancer undergoing hand-assisted laparoscopic colectomy were randomly assigned group or control group. The received 15 mg by mouth 50 ml water three times day, starting day 1. same schedule. Patients allowed resume oral feeding evening 2....
To contribute new multinational findings on basic descriptive features of smoking and cessation, based upon standardised community surveys adults residing in seven low-income middle-income countries 10 higher-income from all regions the world.Data were collected using interviews probability sample survey methods conducted as part WHO World Mental Health Surveys Initiative. Demographic socioeconomic correlates are studied cross-tabulation logistic regression approaches. Within-country weights...
Antiangiogenic therapy is a potent cancer treatment, however, the possibility of recurrence and resistance to this approach remains. Here we show that hypoxia low-nutrition double-deprivation stress induces reversible tumor aggressiveness. In stress-cycle-dependent manner, murine melanoma cells showed morphological changes, up-regulated phospho-Akt, abnormal regulation multiple genes including fibroblast growth factor-21, metabolic regulator, resulting in increased cell proliferation vitro,...
Kawasaki disease (KD) is an acute inflammatory syndrome of unknown etiology that complicated by cardiovascular sequelae. Chronic inflammation (vasculitis) due to KD might cause vascular cellular senescence and endothelial cell damage, a potential atherosclerosis in young adults. This study examined the effect HMG-CoA inhibitors (statins) on cells. Candida albicans water-soluble fraction (CAWS) was administered intraperitoneally 5-week-old male apolipoprotein E-deficient (ApoE-) mice induce...
Journal Article Effects of Demethylallosamidin, a Potent Yeast Chitinase Inhibitor, on the Cell Division Get access Shohei Sakuda, Sakuda Department Fermentation Technology, Osaka University, Yamada-oka 2-1, Suita-shi, 565, Japan Search for other works by this author on: Oxford Academic Google Scholar Yoshihiro Nishimoto, Nishimoto Mikio Ohi, Ohi Makoto Watanabe, Watanabe Seiji Takayama, Takayama JapanCentral Research Laboratories, Ajinomoto Co., Inc., 1-1 Suzuki-cho, Kawasaki-ku, Kawasaki...
Journal Article Breeding of Brewing Yeast Producing a Large Amount β-Phenylethyl Alcohol and Acetate Get access Kazuro Fukuda, Fukuda Foods Liquors Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., 4041 Ami-machi, Inashiki-gun, Ibaraki 300-03, Japan Search for other works by this author on: Oxford Academic Google Scholar Makoto Watanabe, Watanabe Kozo Asano, Asano Hiroyuki Ueda, Ueda Shigenori Ohta Agricultural Biological Chemistry, Volume 54, Issue 1, 1 January 1990, Pages 269–271,...
The prevalence and risk factors for hepatitis delta virus (HDV) infection among Mongolian school children were assessed by detecting the antibody against HDV RNA, through structured interviews. study subjects consisted of 181 with past or ongoing B who investigated during nationwide serosurvey conducted in 2004. to was 6.1%, proportion 13.6% surface antigen (HBsAg)-positive subjects, all whom had RNA. Multivariate logistic regression analyses showed that injections (> 11 times) (odds...
Universal hepatitis B (HB) immunisation is the most effective means for prevention of virus (HBV) infection worldwide. Maintaining vaccine cold chain an essential part a successful programme. Our recent nationwide survey in Mongolia has observed significant urban-rural differences prevalence HBV among vaccinated cohorts.
Evaluation of left ventricular (LV) diastolic function is essential for the management heart failure. We verified whether LV could be evaluated by measuring fractional area change (FAC) using cine cardiovascular magnetic resonance (CMR). collected clinical data from 59 patients who underwent echocardiography and CMR. Normal, impaired relaxation, pseudonormal, restrictive filling were observed in 15, 28, 11, 5 patients, respectively. calculated FAC during first 30% diastole (diastolic-index%)...
Coronary arteritis, a complication of Kawasaki disease (KD), can be refractory to immunoglobulin (IVIG) treatment. To determine the most effective alternative therapy, we compared efficacy different agents in mouse model KD. Vasculitis was induced by injection Candida albicans water-soluble fractions (CAWS) into DBA/2 mouse, followed administration IVIG, etanercept, methylprednisolone (MP), and cyclosporine-A (CsA). At 2 4 weeks, mice were sacrificed, plasma cytokines chemokines measured....
Accidental hypothermia is a serious condition that requires immediate and accurate assessment to determine severity treatment. Currently, accidental evaluated using the Swiss grading system which uses core body temperature clinical findings; however, research has shown not associated with in-hospital mortality in urban settings. Therefore, we developed validated scale for predicting among Japanese patients hypothermia.Data this multi-center retrospective cohort study were obtained from...
Targeted temperature management (TTM) is recommended in the of out-of-hospital cardiac arrest (OHCA) when coma persists after return spontaneous circulation. In setting extracorporeal membrane oxygenation (ECMO) for OHCA patients, TTM associated with good neurological outcomes and Extracorporeal Life Support Organization guidelines. However, optimal targeted these patients has not yet been adequately investigated. This study aimed to compare impact different temperatures on receiving...
The clinical course of our patient suggests the association between chronic pancreatitis and primary sclerosing cholangitis (PSC), as well usefulness prednisolone for treatment this condition. Although alterations in pancreatic duct have been reported, PSC remains uncertain. A long-term follow-up case accompanied by is presented. 58-yr-old man complaining epigastric distress was admitted to hospital July 1990. Endoscopic retrograde cholangio-pancreatography (ERCP) showed a stricture distal...