A5036719321- Kawasaki Disease and Coronary Complications
- Coronary Artery Anomalies
- Neonatal Respiratory Health Research
- Cardiovascular Issues in Pregnancy
- Birth, Development, and Health
- Cardiac Imaging and Diagnostics
- Dermatological and Skeletal Disorders
- Congenital heart defects research
- Genetic and rare skin diseases.
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Function and Risk Factors
- Drug-Induced Ocular Toxicity
- Cardiac Arrhythmias and Treatments
- Glioma Diagnosis and Treatment
- Pericarditis and Cardiac Tamponade
- Vasculitis and related conditions
- Cardiac pacing and defibrillation studies
- SARS-CoV-2 and COVID-19 Research
- Epilepsy research and treatment
- Meningioma and schwannoma management
- Inflammatory Biomarkers in Disease Prognosis
- Ion channel regulation and function
- Cancer and Skin Lesions
- Diet, Metabolism, and Disease
- Viral Infections and Immunology Research
St. Marianna University School of Medicine
2003-2022
Oclaro (Japan)
2015
Nagoya University
1994
Few studies with sufficient statistical power have shown the association of z score coronary arterial internal diameter events (CE) in patients Kawasaki disease (KD) artery aneurysms (CAA).To clarify time-dependent CE occurrence KD CAA.This multicenter, collaborative retrospective cohort study 44 participating institutions included 1006 younger than 19 years who received a angiography between 1992 and 2011.The CE, including thrombosis, stenosis, obstruction, acute ischemic events,...
Background Coronary arterial aneurysms (CAAs) associated with Kawasaki disease (KD) significantly affect prognosis. However, the clinical course of CAAs and factors CAA regression have not been well analyzed. Methods Results The cohort Z-Score 2nd Project Stage study, a multicenter, retrospective, study involving 44 institutions in Japan including 1006 patients KD, was examined. were classified by z score their internal diameter acute phase: small (z<5), medium (5≤z<10), large (z≥10). lower...
Platelet aggregation is generally measured by the optical density method. This method not very sensitive in detecting platelet activation because of poor correlation between formation aggregates and light transmission, inability to detect small aggregates. Recently, a new was developed that detects formed early phase means particle counting technique using scattering.The present study used measure spontaneous (SPA) produced agitation with stirrer bar without agonists patients Kawasaki...
Abstract Background ATP synthesis and cardiac contraction‐related protein production are accelerated in the immature fetal heart by antenatal glucocorticoids ( GC ). This study investigated structural maturity of myocardium underlying signal pathway associated with growth rats that received . Methods Results Dexamethasone DEX ) was given to pregnant for 2 days from day 17 or 19 gestation, hearts 21 fetuses 1‐day‐old neonates were analyzed. Although irregular myofibril orientation observed...
The debate over myocarditis following COVID-19 vaccination is currently a trending topic in medicine. According to the US Centers for Disease Control and Prevention, frequency of myocarditis/pericarditis low (12.6 per million doses), prognosis considered good with rapid symptom recovery.1 Here we report case 15-year-old adolescent male diagnosed after who subsequently underwent multiple cardiac magnetic resonance imaging (cMRI) studies, which showed positive late gadolinium enhancement (LGE)...
The authors declare no conflict of interest.
We report 2 cases of Kawasaki disease (KD) which required surgical interventions long after initial diagnosis. Case 1: Twenty-one years-old male. He was diagnosed as KD at the age 1. Despite he received intravenous gamma-globulin therapy, bilateral giant coronary aneurysms were formed. In addition, multiple include abdominal, iliac and axillary arteries formed simultaneously. Coronary angiography (CAG) thought to be dangerous because artery aneurysm formation. medical follow-up with aspirin...
悪性高熱症は，揮発性吸入麻酔薬や脱分極性筋弛緩薬が誘因と考えられ，周術期における致命的合併症の一つとされている．我々は，最近小児開心術症例で術後劇症悪性高熱症を経験したので，文献的考察をふまえて報告する．症例は11ヶ月男児，診断は心室中隔欠損症，Down症候群である．生後21日，肺動脈絞扼術と動脈管結紮術を施行した．今回根治術として，心室中隔欠損パッチ閉鎖と肺動脈絞扼解除を施行した．術後より40度の高熱が持続したが，循環動態は安定していた．第2病日に急激に右心不全を呈し，胸骨開放で小康をえた．第3病日に42度まで体温が上昇しCPKなどの上昇が認められ悪性高熱症と高度に疑い，ダントロレンの投与を開始し，マットを使用して体温調節を行った．第4病日より解熱傾向となり，特に後遺症を残さず救命できた．悪性高熱は，麻酔中の最高体温と麻酔中体温上昇速度を指標に劇症型と亜型に分けられ，さらに麻酔後に症状が起こる術後型に分類されている．本症例は，術後劇症悪性高熱症と考えられた．術後悪性高熱は，現在でも死亡率が12.2％と高く，心臓手術後の周術期管理で注意が必要である．