Abdoul Karim Sangaré
A5050930062- SARS-CoV-2 and COVID-19 Research
- Dermatological diseases and infestations
- COVID-19 epidemiological studies
- Vector-borne infectious diseases
- Bartonella species infections research
- Viral Infections and Vectors
- vaccines and immunoinformatics approaches
- COVID-19 Clinical Research Studies
- CRISPR and Genetic Engineering
- Mosquito-borne diseases and control
- Child Nutrition and Water Access
- Pneumonia and Respiratory Infections
- T-cell and Retrovirus Studies
- Hepatitis C virus research
- Hemoglobinopathies and Related Disorders
- Respiratory viral infections research
- Zoonotic diseases and public health
- Cutaneous lymphoproliferative disorders research
- Viral Infections and Outbreaks Research
- HIV/AIDS oral health manifestations
- Seventeenth-Century Political and Philosophical Thought
- SARS-CoV-2 detection and testing
- Fungal Infections and Studies
- Antibiotic Use and Resistance
- Mycobacterium research and diagnosis
Centre Pour le Développement des Vaccins-Mali
2020-2023
Institut Mérieux (France)
2023
Mali-Folkecenter
2020-2023
Université des Sciences, des Techniques et des Technologies de Bamako
2015-2021
University of Bamako
2014-2021
Aix-Marseille Université
2015-2016
Centre National de la Recherche Scientifique
2014-2016
Institut de Recherche pour le Développement
2014-2016
Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes
2014-2016
Inserm
2014-2016
SARS-CoV-2 across Africa The impact of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has been hard to track in African countries, largely because patchy data. Wilkinson et al . curated viral genomes collected 2021 from several countries continent. Outbreaks during 2020 each country were initiated by imported cases, mostly Europe. As developed, case numbers likely many times higher than reported, and subsequent waves appear have more severe. Consequently,...
Investment in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing Africa over the past year has led to a major increase number of sequences that have been generated and used track pandemic on continent, now exceeds 100,000 genomes. Our results show an African countries are able sequence domestically highlight local enables faster turnaround times more-regular routine surveillance. Despite limitations low testing proportions, findings from this genomic surveillance study...
Currently, the body louse is only recognized vector of Bartonella quintana , an organism that causes trench fever. In this work, we investigated prevalence bacterium in human lice different African countries. We tested 616 head and 424 from nine countries using real-time polymerase chain reaction targeting intergenic spacer region 2 specific B. genes. Overall, DNA was found 54% 2% lice, respectively. Our results also show there are more positive for poor countries, which determined by gross...
In poor African countries, where no medical and biological facilities are available, the identification of potential emerging pathogens concern at an early stage is challenging. Head lice, Pediculus humanus capitis, have a short life, feed only on human blood do not transmit to their progeny. They are, therefore, perfect tool for xenodiagnosis current or recent infection. This study assessed occurrence bacterial from head lice collected in two rural villages Mali, high frequency infestation...
Abstract The progression of the SARS-CoV-2 pandemic in Africa has so far been heterogeneous and full impact is not yet well understood. Here, we describe genomic epidemiology using a dataset 8746 genomes from 33 African countries two overseas territories. We show that epidemics most were initiated by importations, predominantly Europe, which diminished following early introduction international travel restrictions. As progressed, ongoing transmission many increasing mobility led to emergence...
Small mammals are the natural reservoirs for many zoonotic pathogens. Using molecular tools, we assessed prevalence of bacteria and protozoans in small their ectoparasites Faladjè, Bougouni, Bamoko, Mali. A total 130 belonging to 10 different species were captured, which 74 (56.9%) infested by ectoparasites, including Laelaps echidnina, Xenopsylla cheopis, Amblyomma variegatum, Rhipicephalus sanguineus sensu lato, Haemaphysalis spp. nymphs. DNA Bartonella was found 14/75 (18.7%), 6/48...
Abstract Serological surveys are essential to quantify immunity in a population but serological cross-reactivity often impairs estimates of the seroprevalence. Here, we show that modeling helps addressing this key challenge by considering important between Chikungunya (CHIKV) and O’nyong-nyong virus (ONNV) as case study. We develop statistical model assess epidemiology these viruses Mali. additionally calibrate with paired neutralization titers French West Indies, region known CHIKV...
.Introduction : La fièvre jaune est une arbovirose dont les épidémies ont été notifiées fréquemment dans régions de savane au Mali avec des taux mortalité atteignant 47 %. Contrairement aux savane, cas sont rarement notifiés localités sahéliennes du Mali. Dans un contexte changement climatique, d’augmentation la capacité vectorielle moustiques Aedes responsables transmission jaune, et forte mobilité population à cause conflits armés, le virus circulerait Mali.Objectif Estimer séroprévalence...
Abstract The circulation of Zika virus (ZIKV) in Mali has not been clearly characterized. Therefore, we conducted a serologic survey 793 asymptomatic volunteers >15 years age (2016), and 637 blood donors (2013) to assess the seroprevalence ZIKV infection 2 ecoclimatic regions Mali, tropical savannah warm semiarid region, using ELISA seroneutralization assays. overall was ≈12% increased with age, no statistical difference between male female participants. In study sites detected immunological...
We are currently facing a pandemic of COVID-19, caused by spillover from an animal-originating coronavirus to humans occurring in the Wuhan region China December 2019. From China, virus has spread 188 countries and regions worldwide, reaching Sahel on 2 March 2020. Since whole genome sequencing (WGS) data is very crucial understand spreading dynamics ongoing pandemic, but only limited available date, we have focused our efforts generating first Malian available. Screening 217 patient samples...
Cutaneous bullous adverse drug eruptions are a dreaded complication of use. The purpose this study was to document the epidemiological features, outcomes, and causes these reactions, in particular, Stevens-Johnson syndrome toxic epidermal necrolysis (Lyell disease), teaching hospital Abidjan (Côte d'Ivoire). A retrospective reviewed records severe cutaneous reactions patients managed dermatology department University Hospital Treichville (Abidjan) over period ten years (from September 2000...
Because lice-transmitted infections are a real public health problem, epidemiological studies in different ecoclimatic zones of Africa useful. This article aims to describe the frequency lice infestation, their genotypes, and infection by pathogens regions Koulikoro Mopti. A cross-sectional survey allowed us collect from rural populations. Techniques molecular biology (real-time PCR, standard genotyping) were used for analysis samples. Infestation rates 57% (12/21) among subjects Diankabou,...
Abstract Investment in Africa over the past year with regards to SARS-CoV-2 genotyping has led a massive increase number of sequences, exceeding 100,000 genomes generated track pandemic on continent. Our results show an African countries able sequence within their own borders, coupled decrease sequencing turnaround time. Findings from this genomic surveillance underscores heterogeneous nature but we observe repeated dissemination variants Sustained investment for is needed as virus continues...
Objectives In low-income settings with limited access to diagnosis, COVID-19 information is scarce. September 2020, after the first wave, Mali reported 3086 confirmed cases and 130 deaths. Most reports originated from Bamako, 1532 81 deaths (2.42 million inhabitants). This observed prevalence of 0.06% appeared very low. Our objective was estimate SARS-CoV-2 infection among inhabitants epidemic wave. We assessed demographic, social living conditions, health behaviours knowledges associated...
Abstract We evaluated Ibalizumab (IBA)-containing standardized optimized salvage regimen (with or without a 4-week foscarnet induction) in individuals harboring multidrug-resistant human immunodeficiency virus type 2 (HIV-2). Nine were included; achieved virological suppression after induction with sustained at Week 24 IBA initiation, and an additional individual initiation.
Noma or cancrum oris is a multi-bacterial and opportunistic infection that destroys soft tissue, as well muscle bone, can be fatal. We present rare case of in 32-year-old Malian woman, from whom we isolated an Escherichia coli extended-spectrum beta-lactamase.
Introduction: Malnutrition is a major public health problem in several countries around the world. The aim of this study was to determine impact risk factors for occurrence types malnutrition children aged 6 59 months at URENI CSRéf Commune V. Method and Materials: Sampling exhaustive; sample size 73 children. Results: female sex most represented (55%), age group 12 24 (49.31%) majority were not vaccinated. mothers ranged from 20 34 years (64.38%), mostly uneducated, housewives (89.04%)...
In Mali, coli and Salmonella infections are one of the most common bacterial diseases in outpatients. Treatment these has become challenging due to emergence pathogens with increasing resistance available antimicrobial agents. The aim this study is determine prevalence evaluate antibiotic profile frequently isolated strains bacteria involved Bamako, Mali. study, 400 samples human, animal environmental origin were obtained area. identified by biochemical tests. Disk diffusion method was...