- Breastfeeding Practices and Influences
- Infant Nutrition and Health
- Child Nutrition and Feeding Issues
- Infant Development and Preterm Care
- Obesity, Physical Activity, Diet
- Gestational Diabetes Research and Management
- Maternal Mental Health During Pregnancy and Postpartum
- Digestive system and related health
- Birth, Development, and Health
- Neonatal Respiratory Health Research
- Child Nutrition and Water Access
- Fatty Acid Research and Health
- Food Security and Health in Diverse Populations
- Pediatric health and respiratory diseases
- Childhood Cancer Survivors' Quality of Life
- Infant Health and Development
- Nutritional Studies and Diet
- Celiac Disease Research and Management
- Acute Lymphoblastic Leukemia research
- Neuroscience of respiration and sleep
- RNA modifications and cancer
- Child and Adolescent Health
- Food Allergy and Anaphylaxis Research
- Neuroendocrine regulation and behavior
- Body Composition Measurement Techniques
University of Cincinnati Medical Center
2013-2024
University of California, Davis
1998-2024
University of Cincinnati
2012-2024
Mothers’ Milk Bank
2020
Cincinnati Children's Hospital Medical Center
2009-2016
University of California Davis Medical Center
2010-2014
Texas Children's Hospital
2004
Baylor College of Medicine
2004
Chinese Center For Disease Control and Prevention
2004
Center for Disease Control
2004
Objective. Some mothers have difficulty initiating lactation even when highly motivated to breastfeed. The purpose of this study was determine the incidence and risk factors for suboptimal infant breastfeeding behavior (SIBB), delayed onset lactation, excess neonatal weight loss among mother-infant pairs in a population with high educational levels motivation Methods. All residing Davis, California, who gave birth healthy, single, term at 1 5 area hospitals during 10-month recruitment period...
OBJECTIVE: We characterized breastfeeding concerns from open-text maternal responses and determined their association with stopping by 60 days (stopping breastfeeding) feeding any formula between 30 (formula use). METHODS: assessed support, intentions, in 532 expectant primiparas conducted follow-up interviews at 0, 3, 7, 14, 30, postpartum. calculated adjusted relative risk (ARR) population attributable (PAR) for outcomes concern category day, intentions education. RESULTS: In 2946...
The potential risks and benefits of regular exercise during lactation have not been adequately evaluated. We investigated whether aerobic had any effects on the volume or composition breast milk.
Aware of the important benefits human milk, most U.S. women initiate breastfeeding but difficulties with milk supply lead some to quit earlier than intended. Yet, contribution maternal physiology lactation remains poorly understood. Human fat globules, by enveloping cell contents during their secretion into are a rich source mammary RNA. Here, we pair this non-invasive mRNA RNA-sequencing probe layer transcriptome three stages lactation: colostral, transitional, and mature production. The...
This paper resulted from a conference entitled "Lactation and Milk: Defining refining the critical questions" held at University of Colorado School Medicine January 18–20, 2012. The mission was to identify unresolved questions set future goals for research into human milk composition, mammary development lactation. We first outline unanswered regarding composition (Section I) mechanisms by which components affect neonatal development, growth health recommend models research. Emerging about...
The objectives were to describe weight loss in a multiethnic population of first-born, predominantly breastfed, term infants and identify potentially modifiable risk factors for excess (EWL).Data on prenatal breastfeeding intentions, demographic characteristics, labor delivery interventions outcomes, behaviors, formula pacifier use, onset lactogenesis, nipple type pain collected prospectively. Logistic regression analyses identified independent predictors EWL (≥10% birth weight) by using...
Little is known regarding modifiable factors that may explain sociodemographic disparities in breastfeeding rates among women the United States. Using a mediation model approach, we examined relative contributions of and formula feeding psychosocial explaining intentions.We interviewed 532 expectant first-time mothers exposure to by others (breastfeeding exposure), comfort with ideas comfort) (formula comfort), self-efficacy. We used logistic regression evaluate independent mediating effects...
Time to onset of stage II lactogenesis varies widely, and delayed (OL) is common among first-time mothers in the United States. Higher body mass index, older age, larger infant birth weight are identified risk factors for OL; all known correlates with glucose metabolism. Our objective was prenatally assess maternal biomarkers related metabolic health determine extent which these predict timing OL.We enrolled a population-based sample expectant primiparas attending single prenatal clinic. We...
Factors associated with successful provision of mother's own milk (MOM) for premature infants in a Japanese neonatal intensive care unit (NICU) context are not well known.We determined the independent risk factors low volume at day 4 postpartum and formula feeding time NICU discharge.We reviewed medical records mothers who delivered < 32 weeks' gestation. We maternal, infant, expression variables predictive (1) being less than cohort median (2) discharge, reported as adjusted odds ratios...
Serotonin [5-hydroxytryptamine (5-HT)] is an important local regulator of lactation homeostasis; however, the roles for serotonin reuptake transporter and monoamine oxidase have not been known.The aim study was to determine whether drugs that impact 5-HT affect human physiology.We conducted laboratory studies animal models observational onset copious milk secretion in postpartum women at a university medical center.We studied expecting their first live-born infant; exclusion criteria were:...
Nationally representative data from mother–child dyads that capture human milk composition (HMC) and associated health outcomes are important for advancing the evidence to inform federal nutrition related programs, policies, consumer information across governments in United States Canada as well nongovernment sectors. In response identified gaps knowledge, National Institute of Diabetes Digestive Kidney Diseases NIH sponsored "Workshop on Human Milk Composition—Biological, Environmental,...
Background: A comprehensive approach to breastfeeding support requires elucidation of how metabolic health influences milk production. Objective: We compared indicators in women with severely low output versus those moderate/normal using a case-control study design, nested and external control groups. Design: Cases controls were derived from screened for supply trial, cases defined as (<300 mL/24 hours), (>300 hours). In addition, we included an group exclusively women. All enrolled at 2-10...
Human milk is the ideal source of nutrition for most infants, but significant gaps remain in our understanding human biology. As part addressing these gaps, Breastmilk Ecology: Genesis Infant Nutrition (BEGIN) Project Working Groups 1-4 interrogated state knowledge regarding infant-human milk-lactating parent triad. However, to optimize impact newly generated across all stages research, need remained a translational research framework specific field. Thus, with inspiration from simplified...