A5042398685- Hepatitis B Virus Studies
- Monoclonal and Polyclonal Antibodies Research
- Antibiotics Pharmacokinetics and Efficacy
- HIV Research and Treatment
- Antibiotic Resistance in Bacteria
- Hepatitis Viruses Studies and Epidemiology
- Bacterial Identification and Susceptibility Testing
- Immunotherapy and Immune Responses
- Antimicrobial Resistance in Staphylococcus
- Diabetes and associated disorders
- Cytomegalovirus and herpesvirus research
- Vaccine Coverage and Hesitancy
- Orthopedic Infections and Treatments
- T-cell and Retrovirus Studies
- COVID-19 and healthcare impacts
- Venous Thromboembolism Diagnosis and Management
- Escherichia coli research studies
- Viral gastroenteritis research and epidemiology
- COVID-19 Clinical Research Studies
- Antimicrobial Peptides and Activities
- Immune Cell Function and Interaction
- Glycosylation and Glycoproteins Research
- HIV-related health complications and treatments
- Protein purification and stability
- Respiratory viral infections research
Istituti di Ricovero e Cura a Carattere Scientifico
1992-2023
Policlinico San Matteo Fondazione
1993-2023
University of Pavia
1988-2023
Infectious Diseases and the Research Institute
2020
Pharmacy Research UK
2020
Debiopharm (Switzerland)
2004
University of Padua
2002
PHARM (Italy)
2001
New PEG derivatives were studied for peptide and protein modification, based upon an amino acid arm, Met-Nle or Met-βAla, activated as succinimidyl ester. PEG-Met-Nle-OSu PEG-Met-βAla-OSu react with groups in protein-yielding conjugates stable amide bond. From these may be removed by BrCN treatment, leaving Nle βAla reporter acid, at the site where was bound. The conjugation of its removal treatment assessed on a partial sequence glucagone lysozyme model protein. Furthermore, insulin, three...
Two distinct subtypes of human rotavirus serotype 4 were identified by using neutralizing monoclonal antibodies directed to the major outer capsid glycoprotein, VP7, strains ST3 (subtype 4A) and VA70 4B). Specimens containing rotavirus, obtained from different countries, examined for subtyping solid-phase immune electron microscopy, enzyme-linked immunosorbent assay, and, cell culture-adapted strains, neutralization assay. All 59 as animal antisera classified into either subtype antibodies....
Some studies have suggested that decreased seroconversion rates might be found in premature infants with low birthweight (< 2000 g) following administration of hepatitis B vaccine at birth. The aim the present investigation was to evaluate possible differences seropositive between full-term and preterm after primary vaccination, particular when gestational age or is very low. Two-thousand nine neonates born HBs Ag-negative mothers were vaccinated 10 μg recombinant virus (HBV) vaccine, from...
The American Academy of Pediatrics (AAP) Committee on Infectious Diseases and the Immunization Practices Advisory Centers for Disease Control have recently pointed out that selective strategy immunization against hepatitis B virus (HBV) high-risk populations has not resulted in limitation diffusion disease. In fact, spite vaccine availability more than 10 years, about 200 000 to 300 new cases infection occur United States each year. Therefore, AAP recommended "universal immunization" as a...
Some studies have suggested that decreased seroconversion rates might be found in premature infants with low birthweight (< 2000 g) following administration of hepatitis B vaccine at birth. The aim the present investigation was to evaluate possible differences seropositive between full‐term and preterm after primary vaccination, particular when gestational age or is very low. Two‐thousand nine neonates born HBs Ag‐negative mothers were vaccinated 10 μg recombinant virus (HBV) vaccine,...
Antimicrobial resistance in Gram-negative bacteria, particularly Enterobacteriaceae, has become a leading cause of morbidity and mortality serious public health concern. bacteria carrying extended-spectrum beta-lactamase (ESBL) enzymes now represent significant proportion all isolated from different countries worldwide. Furthermore, the increasing number isolates carbapenemases recent years includes multidrug-resistant (MDR), extensively drug-resistant (XDR), pandrug-resistant (PDR)...
The effects of the type and location polymer grafting on biological activity different mono-PEG derivatives somatostatin analogue RC160 were evaluated. A chemical strategy to obtain alkylation or acylation peptide's α-terminal lysil-ε primary amines was devised. Selective BOC protection two available amines, followed by reaction with PEG reagents removal protecting group, carried out. Chemical characterization, structural studies, evaluation bioconjugates synthesized allowed identification...
AimsThe levels of plasma brain natriuretic peptide (BNP) are known to be elevated in patients with primary pulmonary hypertension (PH). We sought verify the sensitivity and specificity BNP for diagnosis PH HIV infected patients.
<h3>Background</h3> Skin ulcers are a frequent manifestation of systemic sclerosis (SSc). painful, represent cause disability and heavily affect patients' quality life. The presence local infection may be responsible for osteomyelitis (OM) the underlying bone. If gangrene develops, surgical amputation required. At moment is not clear if there predisposing factors to development. <h3>Objectives</h3> To describe population SSc patients affected by cutaneous <h3>Methods</h3> We collected data...