A5020967372- Liver Disease Diagnosis and Treatment
- Parasitic infections in humans and animals
- Congenital Anomalies and Fetal Surgery
- Amoebic Infections and Treatments
- Liver Disease and Transplantation
- Ultrasound and Hyperthermia Applications
- Hepatitis B Virus Studies
- COVID-19 and healthcare impacts
- Ultrasound Imaging and Elastography
- Hepatitis C virus research
- Urological Disorders and Treatments
- Hemoglobinopathies and Related Disorders
- Spectroscopy Techniques in Biomedical and Chemical Research
- Viral gastroenteritis research and epidemiology
- Venous Thromboembolism Diagnosis and Management
- COVID-19 Clinical Research Studies
- Cytomegalovirus and herpesvirus research
- Body Composition Measurement Techniques
- Hepatocellular Carcinoma Treatment and Prognosis
- Infrared Thermography in Medicine
- Parasitic Infections and Diagnostics
- Animal Virus Infections Studies
- Infectious Encephalopathies and Encephalitis
- Parvovirus B19 Infection Studies
- Cardiovascular and Diving-Related Complications
Policlinico San Matteo Fondazione
2013-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2013-2024
University of Pavia
2015-2024
Pharmacy Research UK
2020
Infectious Diseases and the Research Institute
2020
Charité - Universitätsmedizin Berlin
2015
Centre Hospitalier Universitaire d'Angers
2013
The primary aim of this study was to determine the inter-system variability liver stiffness measurements (LSMs) in patients with varying degrees stiffness. secondary inter-observer measurements. 21 individuals affected by chronic hepatitis C and 5 healthy were prospectively enrolled. assessment LSMs performed using six ultrasound (US) systems, four which point shear wave elastography (p-SWE) two 2 D (2D-SWE) systems. Fibroscan (Echosens, France) used as reference standard. Four observers...
To assess the clinical validity of controlled attenuation parameter (CAP) in diagnosis hepatic steatosis a series overweight or obese children by using imperfect gold standard methodology. Consecutive referred to our institution for auxological evaluation obesity minor elective surgery were prospectively enrolled. Anthropometric and biochemical parameters recorded. Ultrasound (US) assessment was carried out ultrasound systems. CAP obtained with FibroScan 502 Touch device (Echosens, Paris,...
Knowledge of variables influencing serology is crucial to evaluate results for the diagnosis and clinical management cystic echinococcosis (CE). We analyzed retrospectively a cohort patients with hepatic CE followed in our clinic 2000-2012 influence several on commercial enzyme-linked immunosorbent assay (ELISA) indirect hemagglutination (IHA) tests. Sera from 171 ≥ 1 cyst, 90 nonparasitic cysts were analyzed. staged according WHO-IWGE classification grouped by activity. A significant...
Performance of Real-Time Strain Elastography, Transient and Aspartate-to-Platelet Ratio Index in the Assessment Fibrosis Chronic Hepatitis CGiovanna Ferraioli1, Carmine Tinelli2, Antonello Malfitano3, Barbara Dal Bello4, Gaetano Filice3, Carlo Filice1, Liver Study Group, Elisabetta Above1, Giorgio Barbarini3, Enrico Brunetti1, Willy Calderon3, Marta Di Gregorio1, Raffaella Lissandrin1, Serena Ludovisi3, Laura Maiocchi3, Giuseppe Michelone3, Mario Mondelli3, Savino F. A. Patruno3, Alessandro...
Available treatments for uncomplicated hepatic cystic echinococcosis (CE) include surgery, medical therapy with albendazole (ABZ), percutaneous interventions and the watch-and-wait (WW) approach. Current guidelines indicate that patients CE should be assigned to each option based on cyst stage size, patient characteristics. However, treatment indications transitional CE3b cysts are still uncertain. These least responsive non-surgical often present as indolent, asymptomatic lesions may not...
To compare results of liver stiffness measurements by transient elastography (TE) obtained in our patients population with that used a recently published meta-analysis.This was single center cross-sectional study. Consecutive chronic viral hepatitis scheduled for biopsy at the outpatient ward Infectious Diseases Department were enrolled. TE carried out using FibroScan™ (Echosens, Paris, France). Liver performed on same day as TE, case procedure. Fibrosis staged according to Metavir scoring...
Background & Aims: Noninvasive assessment of liver stiffness has been increasingly used to evaluate fibrosis instead biopsy, especially in patients with chronic viral hepatitis. The aim this study was assess the performance staging updated ElastPQ® technique (EPIQ7 ultrasound system, Philips Healthcare, Bothell, WA, USA) “real life” setting by using FibroScan as reference standard and understand whether use quality criteria improves technique.
 Methods: This a cross-sectional study:...
AIM:To assess the performance of controlled attenuation parameter (CAP) in patients with chronic viral hepatitis. METHODS:CAP is a new technique that measures liver an ultrasound beam, which directly related to lipid accumulation.Consecutive undergoing biopsy for hepatitis were studied using M probe FibroScan device (Echosens, Paris, France).The estimates st-eatosis decibel per meter (dB/m).An expert operator performed all measurements.Steatosis was graded according Kleiner's...
Human cystic echinococcosis (CE) is a chronic, complex and neglected infection causing severe disease in humans. Hepatic CE cysts are detected classified mainly by using ultrasound. Expert opinion published data suggest that uncomplicated inactive liver do not require treatment only need to be monitored over time ("Watch Wait"). Here we update our findings as 2014 on the "Watch Wait" approach applied inactive, asymptomatic of keep medical community informed. Clinical patients who accessed...
The diagnosis of cystic echinococcosis (CE) is based on imaging. Serology supports imaging in suspected cases, but no consensus exists the algorithm to apply when inconclusive. We performed a retrospective analysis serology results patients with untreated hepatic CE and non-CE lesions, seen from 2005 2017, evaluate their accuracy differential CE. three seroassays for (ELISA RIDASCREEN, indirect hemagglutination (IHA) Cellognost, Western blot LDBIO) clinical characteristics eligible were...
The use of steroid therapy in potentially life-threatening neuroinvasive forms West Nile infection (WNND) is controversial. aim this study to assess the efficacy reducing intrahospital mortality, length stay, and neurological sequelae at discharge.This was a multicenter, retrospective, observational conducted 5 hospitals Northern Italy, headed by Fondazione IRCSS Policlinico San Matteo (Pavia). We extracted all patient data with WNND diagnoses, comparing patients who received treatment did...
Ultrasound is the imaging modality most widely utilized in general population for diagnostic purposes. Controlled attenuation parameter a novel noninvasive method assessing steatosis. Our aim was to investigate whether clinical value of controlled patients referred abdominal ultrasound examinations affected by liver fibrosis.Consecutive were enrolled. and stiffness assessed with FibroScan (Echosens, France). Liver fibrosis staged according published cutoffs measurements. Pearson's or...
Rationale for the study. This cross-sectional multicenter study was conducted to investigate any difference in liver stiffness measurements (LSM), evaluated by transient elastography, between patients affected β thalassaemia major, with and without hepatitis C virus (HCV) infection, healthy blood donors (controls). Secondary aim assess correlation elastography serum ferritin, magnetic resonance imaging (MRI) T2* or superconductive quantum interference device (SQUID) susceptometry values....
Human cystic echinococcosis (CE) is a parasitic infection caused by the larval stage of tapeworm Echinococcus granulosus sensu lato, primarily affecting liver and lungs. Although heart affected in only 0.02-2% all CE cases, considerable number cases have been, continue to be, published. However, due rare occurrence cardiac resulting lack clinical trials, knowledge about various aspects disease remains limited. To obtain clearer picture anatomical, clinical, diagnostic as well therapeutic CE,...
To prospectively assess the cutoff values of a point shear wave measurement (SWM) method for ruling-in and ruling-out significant fibrosis cirrhosis using transient elastography (TE) as reference standard.Consecutive patients with chronic hepatitis C were enrolled. Liver stiffness was assessed SWM implemented on HI VISION Ascendus ultrasound system (Hitachi Ltd, Japan) TE FibroScan® device (Echosens, France). For staging (F>/=2) (F=4) we used cutoffs 7.0 12.0 kiloPascal (kPa), respectively....
Puncture, Aspiration, Injection of scolicidal agent, Re-aspiration is the most widely used percutaneous treatment cystic echinococcosis (CE). Among its perceived risks chemical sclerosing cholangitis, a serious complication due to caustic effect solution on biliary tree, when patent cystobiliary fistula occurs. To simplify protocol, we decided omit injection and reaspiration agent implement full course albendazole (ABZ) therapy instead routine 1-month ABZ prophylaxis. We searched our...
Acute Human Cytomegalovirus (HCMV) Infection is an unusual cause of venous thromboembolism, a potentially life-threatening condition. Thrombus formation can occur at the onset disease or later during recovery and may also in absence acute HCMV hepatitis. It likely due to both vascular endothelium damage caused by impairment clotting balance virus itself. Here we report on two immunocompetent women with splanchnic thrombosis that occurred course infection. Although prevalence patients...