- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- Mycobacterium research and diagnosis
- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Tuberculosis Research and Epidemiology
- Enterobacteriaceae and Cronobacter Research
- Genomics and Phylogenetic Studies
- Infective Endocarditis Diagnosis and Management
- Diphtheria, Corynebacterium, and Tetanus
- Nosocomial Infections in ICU
- Pneumonia and Respiratory Infections
- Streptococcal Infections and Treatments
- Transplantation: Methods and Outcomes
- Antibiotics Pharmacokinetics and Efficacy
- Infections and bacterial resistance
- Infectious Diseases and Mycology
- Neonatal and Maternal Infections
- Insect symbiosis and bacterial influences
- Vector-Borne Animal Diseases
- SARS-CoV-2 detection and testing
- Neutropenia and Cancer Infections
- Leprosy Research and Treatment
- Viral Infections and Vectors
- Veterinary medicine and infectious diseases
University of Pavia
2020-2024
Policlinico San Matteo Fondazione
2008-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2011-2024
University of Catania
2008
Azienda Ospedaliero Universitaria Ospedali Riuniti
2008
Sapienza University of Rome
2008
Ospedale Amedeo di Savoia
2003
University of Turin
2003
Institute of Genetics and Biophysics
1990
Abstract We assessed the clinical relevance and performed molecular characterization of 36 multidrug-resistant strains Corynebacterium striatum. Pulsed-field gel electrophoresis confirmed a single clone, possessing erm(X), tetA/B, cmxA/B, aphA1 genes, but few related subclones. This strain is emerging as pathogen in Italy.
In this study we report the detection of recently described mcr-4 gene in two human isolates Salmonella enterica serovar Typhimurium. The strains were isolated from faecal samples Italian patients with gastroenteritis, collected 2016. identified genes (variant mcr-4.2) differed originally a strain swine origin Italy. species could represent hidden reservoir for mcr genes.
Coagulase-negative staphylococci (CoNS) are commensal on human body surfaces and, for years, they were not considered a cause of bloodstream infection and often regarded as contamination. However, the involvement CoNS in nosocomial is increasingly being recognized. The insertion cannulas intravascular catheters represents primary source entry into bloodstream, causing bacteremia sepsis. They owe their pathogenic role to ability produce biofilms surfaces, such medical devices. In this study,...
ABSTRACT We report on the first case of a catheter-related recurrent bacteremia caused by Kocuria kristinae , gram-positive microorganism belonging to family Micrococcaceae in 51-year-old woman with ovarian cancer. This unusual pathogen may cause opportunistic infections patients severe underlying diseases.
ABSTRACT Staphylococcus pseudintermedius is a veterinary pathogen that has seldom been described as an agent of human disease. Features this probably underreported coagulase-positive species are depicted here through the description graft-versus-host disease-related wound infection caused by multidrug-resistant strain.
ABSTRACT Many studies demonstrate that delayed proper therapy in bloodstream infections caused by Staphylococcus aureus increases the mortality rate, emphasizing need to shorten turnaround time for positive blood cultures. Different techniques are currently available, from phenotypic methods more complex tests such as matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF), real-time PCR (RT-PCR), and fluorescence situ hybridization using peptide nucleic acid...
The spread of carbapenem resistant Enterobacteriaceae (CRE) has recently become a matter concern in public health, mainly due to the wide distribution carbapenemase genes. Italy is country considered endemic for blaKPC Klebsiella pneumoniae (KP). aim this study was depict epidemiological trend CRE one Italian hospital over long period (3 years surveillance, from May 2011 April 2014). Based on defined MIC cut-off specific carbapenems, 164 strains isolated 146 different patients were analyzed...
The genus Asaia has gained much interest lately owing to constant new species discoveries and its role as a potential opportunistic pathogen humans. Here we describe transient bacteremia due lannensis in patient with psychiatric disorder (compulsive self-injection of different substances). Common phenotypic methods identification failed identify this organism, only restriction fragment lenght polymorphism PCR-amplified 16S rRNA gene allowed for proper identification. isolate was highly...
There is still a major debate about the pathogenicity of Lactobacillus spp. and some reports emphasize that these microorganisms are never isolated from endovascular devices. In this report we present case catheter-related bacteremia due to L. rhamnosus in patient who underwent single-lung transplant.
Mycobacterium chimaera (MC) is an environmental, slowly growing, non-tuberculous mycobacterium (NTM) belonging to avium complex (MAC), which recently has been linked severe cardiovascular infections following open heart and vascular surgery. The majority of the diagnostic laboratory tests used in routine are not able distinguish MC from M. intracellulare (MI), because great genetic similarity existing between these two species. Genotype NTM-DR™ represents a valid method differentiate...
Bacillus cereus has sometimes been implicated in food poisoning and opportunistic infections of seriously ill patients. This report describes an unusual case persistent bacteremia multiple organ failure associated with B. a patient admitted to our institution for lung cancer. The was undergoing treatment antimicrobial agent (imipenem) that shown be effective against the micro-organism vitro. No portal entry strain detected. After vancomycin, also vitro, no clinical improvement noted died....
Abstract Complete interferon-γ receptor 1 deficiency is a monogenic primary immunodeficiency caused by IFNGR1 germline defects, with autosomal dominant or recessive inheritance, which results in invasive mycobacterial diseases varying degrees of severity. Most the mutations are homozygous loss-of-function single-nucleotide variants, whereas large genomic deletions and compound heterozygosity have been very rarely reported. Herein we describe clinical presentation, diagnosis, successful...
A 64-year-old woman presented to Our Department with 2 weeks history of fever and cough. Through a series radiological invasive diagnostic studies we finally reach an unexpected diagnosis
Mycobacterium senegalense is a Non-Tuberculous (NTM) belonging to the M. fortuitum group, often associated with veterinary diseases, such as bovine farcy. However, it can also cause human infections and appears be involved in Catheter-Associated Infections immunocompromised patients. Here, we report first Italian isolation of strain from 16-year-old oncological female patient being treated at Fondazione IRCCS Policlinico San Matteo Pavia (Italy). Following pain Port-a-Cath site, pus culture...