A5067221476- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Liver Diseases and Immunity
- Atrial Fibrillation Management and Outcomes
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Arrhythmias and Treatments
- Hepatitis Viruses Studies and Epidemiology
- Celiac Disease Research and Management
- Cardiac pacing and defibrillation studies
- Photosynthetic Processes and Mechanisms
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Valve Diseases and Treatments
- COVID-19 Clinical Research Studies
- Algal biology and biofuel production
- Venous Thromboembolism Diagnosis and Management
- Lipoproteins and Cardiovascular Health
- COVID-19 and healthcare impacts
- Ion Transport and Channel Regulation
- Acute Ischemic Stroke Management
- Immune Cell Function and Interaction
University of L'Aquila
2024
Regione Emilia-Romagna
2022-2024
Università Campus Bio-Medico
2024
Società Italiana di Cardiologia
2018-2023
Agenzia Regionale Prevenzione e Ambiente della Regione Emilia-Romagna
2022
Clinical Trial Investigators
2022
Ospedale Maggiore
2011-2021
University of Campania "Luigi Vanvitelli"
2010-2020
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
1990-2019
Ospedale Maggiore Carlo Alberto Pizzardi
2019
In patients with ST-segment elevation myocardial infarction (STEMI), percutaneous coronary intervention (PCI) of the culprit lesion reduces risk cardiovascular death or infarction. Whether PCI nonculprit lesions further such events is unclear.
A prospective cardiologic evaluation was performed in 83 consecutive patients with transient cerebral ischemia or mild stroke and without symptoms electrocardiographic signs of ischemic heart disease. Patients were studied an exercise test; a positive test followed by Thallium-201 myocardial scintigraphy. Results compared to those obtained group age sex-matched healthy subjects submitted the same study protocol. Asymptomatic coronary artery disease detected 28% cerebrovascular adequate test....
Screening of undocumented migrants or refugees for hepatitis B virus (HBV), C (HCV) and human immunodeficiency (HIV) infections has been offered free charge from bureaucratic procedures since 2012 at four primary-level clinical centres in Naples Caserta, Italy. Of 926 visiting one the January to June 2013, 882 (95%) were screened surface antigen (HBsAg), total core antibody (anti-HBc) antibodies against HCV HIV. individuals enrolled, 78 (9%) HBsAg positive, 35 (4%) anti-HCV positive 11 (1%)...
Cow milk allergy is a common disease of infancy, often associated with atopic dermatitis (AD). Avoidance cow (CM) implies the use alternative dietary supports such as mammalian milks. In this study, we assessed tolerability and clinical effect ass's (AM), when compared largely used goat's (GM) in single-blind, controlled, randomized crossover. Twenty-eight children AD ascertained to CM were enrolled. The AM or GM for 6 months, then switched other further 3 months. SCORAD index (SI) visual...
Abstract The aim of the study was to evaluate clinical and virological differences in HBV reactivation between patients with overt occult infection. Twenty‐three consecutive symptomatic occurring during or after immunosuppressive therapy were enrolled a retrospective study: 10 infection (overt group) 13 (occult group). Twenty‐one treated nucleot(s)ide analogues reactivation. Regimens including rituximab fludarabine administered more frequently group (61% vs. 31%, respectively). severe (40%)...
The data on hepatitis b virus (HBV) infection in immigrants population are scanty. porpoise of this study was to define the demographic, virological, and clinical characteristics subjects infected with HBV chronic a cohort living Naples, Italy. A screening for offered 1,331 immigrants, whom 1,212 (91%) (831 undocumented 381 refugees) accepted were screened B surface antigen (HBsAg) anti-hepatitis core antibody (HBc). Those found be HBsAg positive further investigated at third-level...
Abstract Dendritic Cells (DCs) recognize infectious non-self molecules and engage the adaptive immune system thereby initiating long lasting, antigen-specific responses. As such, ability to activate DCs is considered a key tool enhance efficacy quality of vaccination. Here we report novel immunomodulatory sulfolipid named β-SQDG18 that prototypes class natural-derived glycolipids able prime human by TLR2/TLR4-independent mechanism trigger an efficient response in vivo . induces maturation DC...
Importance In patients with multivessel coronary artery disease (CAD) presenting ST-segment elevation myocardial infarction (STEMI), complete revascularization reduces major cardiovascular events compared culprit lesion–only percutaneous intervention (PCI). Whether also improves angina-related health status is unknown. Objective To determine whether angina in STEMI and CAD. Design, Setting, Participants This secondary analysis of a randomized, multinational, open label trial patient-reported...
Aging is associated to a progressive establishing of chronic inflammatory state linked continuous long exposure antigens. Since IL‐15 stimulates the proliferation memory T cells and immunosenescence characterized by accumulation exhaustion naive cells, we analyzed levels in sera from 30 ultralongeval subjects with respect those young old adults. were assayed immunoenzymatic methods. Ultralongeval displayed significantly higher both controls. No statistical difference was found between These...
Abstract Occult hepatitis B virus (HBV) infection in patients with chronic C has been found associated severe liver damage, low response to interferon treatment and increased risk of developing HCC. However, doubts remain on its clinical impact the sensitivity specificity detection. HBV‐DNA was sought by PCR plasma, peripheral blood mononuclear cells (PBMCs) compartments 89 biopsy proven C, using sets primers for core (“c”), surface (“s”), x (“x”) regions HBV genome. defined presence at...
<b><i>Background:</i></b> Incidence of acute intracerebral hemorrhage (ICH) increases with age, but there is a lack information about ICH characteristics in the oldest-old (age ≥85 years). In particular, need for hematoma volume, which included most clinical scales prediction mortality patients. Many these also assume that, independent characteristics, have higher than younger elderly patients 65-74 However, supporting evidence from cohort studies limited. We...
Interleukin‐18 (IL‐18), a pro‐inflammatory cytokine that plays an important role in the T‐cell‐helper type 1 response, is new member of family cytokines produced brain. CD30 marker 2 lymphocytes. We evaluated IL‐18 and serum levels 10 patients affected by moderate‐severe depression (MSD). demonstrated for first time MSD were significantly higher than those healthy donors. On contrary, no significant difference was found between compared with These data strengthen hypothesis disease...