A5053403648- Polyomavirus and related diseases
- Mycobacterium research and diagnosis
- Parvovirus B19 Infection Studies
- Bacterial Identification and Susceptibility Testing
- Bacterial biofilms and quorum sensing
- Antimicrobial Resistance in Staphylococcus
- COVID-19 Clinical Research Studies
- Immune Cell Function and Interaction
- CAR-T cell therapy research
- Viral-associated cancers and disorders
- Virus-based gene therapy research
- Cytomegalovirus and herpesvirus research
- Tuberculosis Research and Epidemiology
- Infectious Diseases and Mycology
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Actinomycetales infections and treatment
- Transplantation: Methods and Outcomes
- Genomics and Phylogenetic Studies
- Biochemical and Structural Characterization
- 3D Printing in Biomedical Research
- COVID-19 and healthcare impacts
- Mesenchymal stem cell research
- Enterobacteriaceae and Cronobacter Research
- Full-Duplex Wireless Communications
- Leprosy Research and Treatment
Policlinico San Matteo Fondazione
2018-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2018-2024
University of Pavia
2020-2024
Anti-inflammatory and immune-modulatory therapies have been proposed for the treatment of COVID-19 its most serious complications. Among others, use mesenchymal stromal cells (MSCs) is under investigation given their well-documented anti-inflammatory immunomodulatory properties. However, some critical issues regarding possibility that MSCs could be infected by virus raised. Angiotensin-converting enzyme 2 (ACE2) type II transmembrane serine protease (TMPRSS2) are main host cell factors...
Coagulase-negative staphylococci (CoNS) are commensal on human body surfaces and, for years, they were not considered a cause of bloodstream infection and often regarded as contamination. However, the involvement CoNS in nosocomial is increasingly being recognized. The insertion cannulas intravascular catheters represents primary source entry into bloodstream, causing bacteremia sepsis. They owe their pathogenic role to ability produce biofilms surfaces, such medical devices. In this study,...
Advanced therapy medicinal products (ATMPs) are novel drugs based on genes, cells or tissues developed to treat many different diseases. Stability studies of each new ATMP need be performed define its shelf life and guarantee efficacy safety upon infusion, these presently guidelines originally drafted for standard pharmaceutical drugs, which have properties stored in conditions quite from cell products. The aim this report is provide evidence-based information stability ATMPs that will...
Mycobacterium chimaera (MC) is an environmental, slowly growing, non-tuberculous mycobacterium (NTM) belonging to avium complex (MAC), which recently has been linked severe cardiovascular infections following open heart and vascular surgery. The majority of the diagnostic laboratory tests used in routine are not able distinguish MC from M. intracellulare (MI), because great genetic similarity existing between these two species. Genotype NTM-DR™ represents a valid method differentiate...
Polyomavirus BK (BKPyV)-associated nephropathy (BKPyV-nephropathy) remains a significant cause of premature kidney allograft failure. In the absence effective antiviral treatments, current therapeutic approaches rely on immunosuppression (IS) reduction, possibly at risk inducing alloimmunity. Therefore, we sought to explore long-term effects tailored viro-immunologic surveillance and treatment program for BKPyV development alloimmunity graft outcome. Forty-five pediatric transplant...
A 64-year-old woman presented to Our Department with 2 weeks history of fever and cough. Through a series radiological invasive diagnostic studies we finally reach an unexpected diagnosis
Mycobacterium senegalense is a Non-Tuberculous (NTM) belonging to the M. fortuitum group, often associated with veterinary diseases, such as bovine farcy. However, it can also cause human infections and appears be involved in Catheter-Associated Infections immunocompromised patients. Here, we report first Italian isolation of strain from 16-year-old oncological female patient being treated at Fondazione IRCCS Policlinico San Matteo Pavia (Italy). Following pain Port-a-Cath site, pus culture...
Coagulase-Negative Staphylococci (CoNS) are commensal on human body surfaces and for years, they were not considered a cause of bloodstream infection often regardered as contamination. However, the association CoNS with nosocomial is increasingly recognized. The insertion cannulas intravascular catheters represents first source entry into bloodstream, causing bacteremia sepsis. They owe their pathogenic power to ability produce biofilms surfaces, such medical devices. In this study, we...
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A 64-year-old woman presented to Our Department with 2 weeks history of fever and cough. Through a series radiological invasive diagnostic studies we finally reach an unexpected diagnosis Tsukamurella pneumonia; Diagnosing ILD is dynamic process, that the reason why complex cases discussed in multidisciplinary team may need be reconsidered light evolution disease results performed exams flexible approach. spp. obligate aerobic, Gram-positive, weakly acid-fast, non-motile bacilli belongs...