A5102836982- Reproductive Biology and Fertility
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Ovarian function and disorders
- Endometriosis Research and Treatment
- Plant Parasitism and Resistance
- Reproductive Health and Technologies
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive System and Pregnancy
- Plant-Microbe Interactions and Immunity
- Pneumocystis jirovecii pneumonia detection and treatment
- Prenatal Screening and Diagnostics
- Plant Pathogenic Bacteria Studies
- Autophagy in Disease and Therapy
- Pneumonia and Respiratory Infections
- Antibiotic Use and Resistance
- Growth Hormone and Insulin-like Growth Factors
- Retinoids in leukemia and cellular processes
- Ectopic Pregnancy Diagnosis and Management
- Kruppel-like factors research
- Neuroblastoma Research and Treatments
- Plant and fungal interactions
- Reproductive Physiology in Livestock
- vaccines and immunoinformatics approaches
- Toxoplasma gondii Research Studies
Ruijin Hospital
2017-2024
Shanghai Jiao Tong University
2014-2024
Sichuan Center for Disease Control and Prevention
2017-2024
Children's Hospital of Chongqing Medical University
2024
Chongqing Medical University
2024
Renji Hospital
2014-2024
Chongqing University
2023
Hainan General Hospital
2021
China Agricultural University
2018-2019
Northwest A&F University
2014
Downy mildew is one of the most destructive diseases grapevine, causing tremendous economic loss in grape and wine industry. The disease agent Plasmopara viticola an obligate biotrophic oomycete, from which over 100 candidate RXLR effectors have been identified. In this study, 83 effector genes (PvRXLRs) were cloned P. isolate "JL-7-2" genome. results yeast signal sequence trap assay indicated that are secretory proteins. biological activities subcellular localizations all analyzed via a...
Abstract STUDY QUESTION Does the transfer of single low-grade blastocysts result in acceptable reproductive and perinatal outcomes compared to good-grade blastocysts? SUMMARY ANSWER The resulted a reduced live birth rate around 30% (14% for very blastocysts) 44% blastocysts, but does not lead more adverse outcomes. WHAT IS KNOWN ALREADY It is known that can births. However, current studies are limited by relatively small sample sizes single-centre designs. Furthermore, evidence on after...
ABSTRACTTuberculosis (TB) is more prevalent in rural than urban areas China, and delineating TB transmission patterns populations could improve control. We conducted a prospective population-based study of culture-positive pulmonary patients diagnosed between July 1, 2009 December 31, 2020 two counties China. Genomic clusters were defined with threshold distance 12-single-nucleotide-polymorphisms, based on whole-genome sequencing. Risk factors for clustering identified by logistic...
The grapevine downy mildew pathogen Plasmopara viticola secretes a set of RXLR effectors (PvRXLRs) to overcome host immunity and facilitate infection, but how these function is unclear. Here, the biological PvRXLR131 was investigated via heterologous expression. Constitutive expression in Colletotrichum gloeosporioides significantly enhanced its pathogenicity on leaves. Arabidopsis promoted Pseudomonas syringae DC3000 P. (hrcC- ) growth as well suppressed defence-related callose deposition....
Abstract GnRH antagonist negatively affects endometrial receptivity in vitro fertilization (IVF) cycles, however, its underlying mechanism remains unclear. To explore target molecules, we studied endometria the window phase of fixed antagonist, low-dose flexible agonist long protocol, and untreated control groups. There were 384 differentially expressed genes (DEGs) group with greater than twofold expression change compared 197 DEGs between groups, majority which associated natural killer...
Embryos with low morphological scores can still develop to the blastocyst stage and result in good clinical outcomes. However, no studies have reported possible effects of transferring cryopreserved blastocysts developed from poor-quality cleavage embryos on pregnancy perinatal In this retrospective study, value derived day 3 during vitro fertilization embryo transfer procedures was evaluated. According quality which transferred originated, patients were divided into three groups: (111...
Tuberculosis (TB) infection prevention and control (IPC) in healthcare facilities is key to reducing transmission risk. A framework for systematically improving TB IPC through training mentorship was implemented 9 China from 2017 2019.
The fitness of multidrug-resistant tuberculosis (MDR-TB) is thought to be an important determinant a strain's ability transmitted. Studies in the laboratory have demonstrated that MDR-TB strains reduced but relative transmissibility versus drug-susceptible (DS) TB human populations remains unresolved. We used data on genomic clustering from our previous molecular epidemiological study Songjiang (2011-2020) and Wusheng (2009-2020), China, compare DS-TB. Genomic clusters were defined with...
Gonadotropin-releasing hormone antagonist (GnRH-ant) has been shown to negatively influence endometrial receptivity. Reducing the GnRH-ant dose during controlled ovarian stimulation (COS) when using a protocol may be beneficial embryo implantation. However, whether or not minimum daily should individualized remains uncertain. In this retrospective study, we aimed elucidate feasibility and effectiveness of moderately reducing 0.125 mg, then adjusting 0.25 mg based on subsequent luteinizing...
Plasmopara viticola, the causal oomycete of grapevine downy mildew disease, secrets a series RXLR effectors to manipulate host immunity. In this study, we characterized role effector P. PvRXLR159, in plant–microbe interaction. Transcription PvRXLR159 viticola was induced early stage infection (Vitis vinifera 'Thomson Seedless'). Further results revealed that contains functional signal peptide and its C terminus essential inhibit cell death by elicitors, INF1 BAX, Nicotiana benthamiana....
Abstract Background Poor response patients with PCOS who are not susceptible to gonadotropin stimulation more likely have canceled cycles or poor clinical outcomes during IVF treatment. However, some limitations exist in the present therapies. In this study, we evaluated effects of using transvaginal ovarian drilling (TVOD) followed by controlled (COS) from second day these responders. Methods During IVF, 7 responders and 28 (14 normal 14 high responders) were recruited. All received COS...
Abstract Background Among the POSEIDON criteria, group 3 and 4 have an expected low prognosis. For those patients with inadequate ovary reserve, embryo accumulated from consecutive oocyte retrieval cycles for multiple frozen-thawed transfers (FET) has become more common. It is necessary to inform them of pregnancy outcomes after single or FET before treatment. However few studies about cumulative live birth rate (CLBR) prognosis been reported. Methods This retrospective study included 4712...