A5033231205- Tuberculosis Research and Epidemiology
- Pneumocystis jirovecii pneumonia detection and treatment
- Diagnosis and treatment of tuberculosis
- Renal Diseases and Glomerulopathies
- HIV/AIDS Research and Interventions
- Pneumonia and Respiratory Infections
- Leprosy Research and Treatment
- Mycobacterium research and diagnosis
- Infectious Diseases and Tuberculosis
- Infectious Diseases and Mycology
- Fungal Infections and Studies
- HIV/AIDS Impact and Responses
- Hematological disorders and diagnostics
- Actinomycetales infections and treatment
- Autoimmune Bullous Skin Diseases
- Lymphatic Disorders and Treatments
- Eosinophilic Disorders and Syndromes
- Venomous Animal Envenomation and Studies
- HIV/AIDS drug development and treatment
- Neonatal Health and Biochemistry
- Biomedical Research and Pathophysiology
- Parasitic infections in humans and animals
- Rabies epidemiology and control
- Pharmacological Effects and Toxicity Studies
- Renal Transplantation Outcomes and Treatments
Center for Global Health
2011-2024
Centers for Disease Control and Prevention
2013-2024
Oregon Medical Research Center
2024
New York Proton Center
2024
University of Pittsburgh
2024
Communities In Schools of Orange County
2024
Lindsay Unified School District
2024
Federal Ministry of Health
2020
National Health Laboratory Service
2020
Ministry of Health, Community Development, Gender, Elderly and Children
2020
Worldwide, tuberculosis (TB) is the leading cause of death from a single infectious disease and especially deadly for persons living with human immunodeficiency virus (HIV) infection. Although recent trends point to modest progress towards global TB targets, more focus commitment needed find, cure, prevent TB.
Although tuberculosis (TB) is curable and preventable, in 2019, TB remained the leading cause of death from a single infectious agent worldwide among persons living with HIV infection (1). The World Health Organization's (WHO's) End Strategy set ambitious targets for 2020, including 20% reduction incidence 35% number deaths compared 2015, as well zero TB-affected households facing catastrophic costs (defined exceeding annual household income) (2). In addition, during 2018 United Nations...
Shigella dysentery caused 65% of all cases acute renal failure (ARF) seen in children treated at the Christian Medical College Hospital, Vellore, during 33 months ending September 1977. In 40 with ARF secondary to shigella dysentery, haematological findings suggested that they were suffering from haemolytic-uraemic syndrome, and glomerular hypercellularity fibrin deposition present 12 patients whose histology could be studied. Peritoneal dialysis was main element treatment: 43% who underwent...
High attack rates among vaccinated young adults reported during the 2006 mumps outbreak in United States heightened concerns regarding vaccine failure.
To measure progress in implementing co-trimoxazole prophylaxis (CTXp) (trimethoprim plus sulfamethoxazole) and isoniazid preventive therapy (IPT) policy recommendations, identify barriers to the development of national policies pinpoint challenges implementation.In 2007 we conducted by e-mail a cross-sectional survey World Health Organization (WHO) HIV/AIDS programme officers 69 selected countries having high burden infection with HIV or HIV-associated tuberculosis (TB). The...
Multidrug resistant and extensively drug tuberculosis (TB) have become major threats to control of globally. The rates anti-TB resistance in Uganda are not known. We conducted a national survey investigate the levels patterns first second line drugs among new previously treated sputum smear-positive TB cases.Sputum samples were collected from nationally representative sample patients registered at diagnostic centers during December 2009 February 2011 using weighted cluster sampling method....
In 2004, the U.S. President's Emergency Plan for AIDS Relief (PEPFAR), with CDC as a major government implementing agency, began providing HIV antiretroviral therapy (ART) worldwide. Through suppression of viral load, effective ART reduces morbidity and mortality among persons infection prevents vertical sexual transmission.To describe program impact, data were analyzed from all PEPFAR programs six countries that have conducted nationally representative Population-based Impact Assessment...
1. To assess inter- and intra-observer variation in the histopathological reporting of cervical colposcopic biopsies using a histologic modification cytological Bethesda grading system; 2. to determine profile those cases which resulted diagnostic disagreement.Consecutive (n = 125) were assessed independently by six experienced histopathologists. Cases classified as normal, low grade squamous intraepithelial lesion or high lesion. Six months later process was repeated. The degree inter kappa...
We describe a two generation family with variable ulnar and radial ray reduction midline craniofacial abnormalities. The features suggest diagnosis of Weyers9 ray/oligodactyly syndrome originally described in isolated cases. Syndromes are briefly reviewed the relationship between limb bud development discussed.
To help achieve the End TB Strategy target of a 90% reduction in tuberculosis (TB) incidence by 2030, member states United Nations High-Level Meetings on called for improving provision preventive treatment (TPT) household contacts persons with TB, who are at increased risk infection and disease. However, TPT use among worldwide remained 21% 2023. The International Union Against Tuberculosis Lung Disease, Uganda Ministry Health, CDC piloted comprehensive approach increasing case finding...
Eighty patients with non-insulin-dependent diabetes mellitus being treated in a south Indian hospital were biopsied to confirm suspected nondiabetic renal disease (NDRD). The positive predictive value of the standard clinical indicators for NDRD presence or absence diabetic retinopathy was 54 and 87%, respectively. These values are higher than those given by comparable studies Western populations. This is probably due prevalence population India, especially proliferative glomerulonephritis,...
In sub-Saharan Africa, patients with advanced HIV experience high mortality during the first few months of antiretroviral therapy (ART), largely attributable to tuberculosis (TB). We evaluated cost-effectiveness TB diagnostic strategies reduce this early mortality.We developed a decision analytic model estimate incremental cost, deaths averted, and 3 algorithms. The base case represents current practice (symptoms screening, sputum smear, chest radiography) in many resource-limited countries...
John, George T.; Mathew, Mary; Snehalatha, Elizabeth; Anandi, V.; Date, Anand; Jacob, C. K.; Shastry, J. C.M. Author Information
This report describes 16 cases of candidiasis, seven aspergillosis, four mucormycosis, two cryptococcosis and one nocardiosis in which the kidney was involved. Characteristic patterns renal tissue injury were seen each these infections. Candida nocardia caused microabscesses cortex medulla. Tissue destruction minimal with candidiasis when present confined to papillary tips produced only mild impairment function. Aspergillus mucor invaded blood vessels resulting thrombosis extensive necrosis...
Clinical, hematological, and renal biopsy findings in 19 unselected patients with failure following snake bite, including eight bitten by Russell's viper, are presented. Hematological were variable did not influence treatment. Renal histology was a good guide to prognosis; normal recovered conservative management, those tubular necrosis responded well dialysis, while cortical only partially. Peritoneal dialysis found be an adequate form of treatment the majority patients.
Background Non-tuberculous mycobacteria (NTM) can cause pulmonary infection and disease especially among people living with HIV (PLHIV). PLHIV NTM may clinically present one of the four symptoms consistent tuberculosis (TB). We describe prevalence Mycobacterium complex (MTBC) isolated who presented for care treatment. Methods All patients presenting treatment services at 22 clinical sites in Botswana were offered screening TB recruited. Patients had ≥1 symptom asked to submit sputa Xpert...
Tuberculosis preventive treatment (TPT) decreases morbidity and mortality among persons living with human immunodeficiency virus infection but remains underutilized. The U.S. President's Emergency Plan for AIDS Relief has committed to providing TPT all eligible receiving antiretroviral therapy by 2021.
John, George T.; Mathew, Mary; Snehalatha, Elizabeth; Anandi, V.; Date, Anand; Jacob, C. K.; Shastry, J. C.M. Author Information