<h3>Objectives:</h3> The aim of this study was to prospectively perioperative variables associated with revision after shunt surgery for adult hydrocephalus. <h3>Methods:</h3> Two protocols were designed risk factors during insertion. Over 10 years (1995–2004), 450 (age &gt;16 years) patients first time implantations studied. Patients who had been treated endoscopic third ventriculostomy excluded from the study. All shunts designated as meeting one two end points: (1) failure requiring...

This study was undertaken to investigate whether a gradual reduction of the valve setting (opening pressure) decreases complication rate in patients with idiopathic normal-pressure hydrocephalus (iNPH) treated ventriculoperitoneal (VP) shunt.In this prospective double-blinded, randomized, controlled, dual-center study, VP shunt an adjustable implanted 68 iNPH, randomized into two groups. In one group (the 20-4 group) initially set 20 cm H₂O and gradually reduced 4 H2O over course 6-month...

Surgery is the main treatment modality for intracranial meningiomas, but data on short-term surgical outcome are limited. The aim of this Swedish nationwide registry-based study was to benchmark 30-day complication rate in a cohort meningioma patients using from brain tumor registry (SBTR). Furthermore, we investigated outcomes asymptomatic patients. Data were collected SBTR all adults with histopathologically verified between 2009 and 2015. Patient symptoms, characteristics, complications...

<h3>BACKGROUND AND PURPOSE:</h3> Ventricular enlargement in idiopathic normal pressure hydrocephalus is often estimated using the Evans index. However, sensitivity of index to estimate changes ventricular size postoperatively has been questioned. Here, we evaluated postoperative change ventricle relation shunt response patients with hydrocephalus, by comparing volume and <h3>MATERIALS METHODS:</h3> Fifty-seven underwent high-resolution MR imaging preoperatively 6 months after insertion....

<h3>Background and objectives</h3> Written verbal communication skills are important for all physicians. While taught assessed in medical school, students report limited instruction written skills. This study examined the impact of a curriculum delivered during 6-week clinical rotation Internal Medicine on objective assessment students' <h3>Methods</h3> The consisted two educational programmes: student tutorial resident feedback workshop. was conducted from March 2012 to January 2013 at...

Abstract Background Many meningiomas are detected incidentally and remain asymptomatic until intervention. The goal of this study was to describe the management outcome in group surgically treated meningiomas. Methods From 2004 2017, 45 patients with meningioma were at Sahlgrenska University Hospital, their medical records imaging data analyzed. cases matched symptomatic ones respect age diagnosis, location, WHO (World Health Organization) grade, Simpson grade. Results Time from diagnosis...

Abstract Purpose To study the long-term effect of transsphenoidal surgery (TSS) on headache in patients with non-functioning pituitary adenoma (NFPA) and identify factors predicting relief following TSS. Methods We evaluated 101 consecutive NFPA who underwent TSS from September 2015 to December 2021, preoperatively 12-months post-surgery, by using Migraine Disability Assessment (MIDAS) questionnaire. Health-related quality life (QoL) was assessed EQ-5D visual analogue scale (EQ-VAS). Results...

To evaluate the use of preoperative virtual Magnetic Resonance Elastography (vMRE) for patients undergoing transsphenoidal resection pituitary adenomas (PA).Ten (60.2 ± 19.6 years; 8 males) were prospectively examined with vMRE-method prior to surgery. vMRE-images, reflecting tissue stiffness reconstructed. From these images, histograms as well mean values over tumor body extracted. Finally, vMRE-data was compared PA consistency at surgery blinded vMRE.In all patients, successful...

OBJECT The study aim was to examine the effect of gradually reducing opening pressure on symptoms and signs in shunt treatment idiopathic normal hydrocephalus (iNPH). METHODS In this prospective double-blinded, randomized, controlled, double-center patients with iNPH, a ventriculoperitoneal an adjustable Codman Medos Valve implanted 68 randomized into 2 groups. 1 group (the 20–4 group) valve setting initially set 20 cm H O reduced 4 over course 6-month period. other 12 group), kept at medium...

Determination of the ventricle size in idiopathic normal pressure hydrocephalus (iNPH) is essential for diagnosis and follow-up shunt results. Fully automated segmentation methods are anticipated to optimize accuracy time efficiency ventricular volume measurements. We evaluated preoperative postoperative measurements iNPH by a magnetic resonance imaging (MRI)-based licensed software fully quantitative assessment.

Background The assessment of pituitary tumor (PT) volume is important in the treatment and follow-up patients with PT. Previously, PT estimation has been performed by conventional geometric equations (CGE) such as abc/2 (simplified ellipsoid equation) 4πr 3 /3 (sphere), both presuming a symmetric shape, which occurs uncommonly In contrast, three-dimensional (3D) voxel-based software segmentation takes irregular asymmetric shapes that PTs often possess into account might be more accurate...

Abstract Introduction The relationship between neurochemical changes and outcome after shunt surgery in idiopathic normal pressure hydrocephalus (iNPH), a treatable dementia gait disorder, is unclear. We used baseline ventricular CSF to explore associations outcome, shunting, of biomarkers selected reflect range pathophysiological processes. Methods In 119 consecutive patients with iNPH, the iNPH scale was before quantify outcome. Ventricular collected perioperatively analyzed for...

Glioblastoma (GBM) is the most aggressive primary brain tumor with a median survival of less than 15 months, emphasizing need for better treatments. Immunotherapy as treatment improving or aiding patient's own immune defense to target has been suggested GBM. A randomized clinical trial adoptive cell transfer using ALECSAT (Autologous Lymphoid Effector Cells Specific Against Tumor Cells) currently ongoing in Sweden. Here we performed paired pre-clinical study investigate composition and vitro...

Objectives Despite the limited invasiveness of endoscopic transsphenoidal surgery (ETSS), some degree nasal structure destruction is unavoidable. Our objective was to evaluate sinonasal morbidity and self-reported health before 6 months after ETSS for pituitary tumors, identify possible predictive factors deterioration in health. Design Prospective observational cohort study. Setting University tertiary referral hospital. Participants Totally 109 consecutive adult patients undergoing tumors...

OBJECTIVE MRI volumetry could be used as an alternative to invasive tests of shunt function. In this study, the authors aimed assess difference in ventricular volume (VV) before and after surgery at different performance levels (PLs) shunt. METHODS This study was a randomized, double-blind trial with crossover design. The sample consisted 36 patients (25 men, 11 women) median age 76 years. All had idiopathic normal pressure hydrocephalus (iNPH) received Strata regional hospital Östersund,...

Abstract Background Levels of the biomarkers amyloid-β 1–42 (Aβ42), tau and phosphorylated (p-tau) are decreased in cerebrospinal fluid (CSF) patients with idiopathic normal pressure hydrocephalus (iNPH). The mechanism behind this is unknown, but one potential explanation dilution by excessive CSF volumes. aim study was to investigate presence a effect, studying relationship between ventricular volume (VV) levels biomarkers. Methods In cross-sectional observational study, preoperative...

Ventricular shunt insertion is a commonly performed neurosurgical procedure but few studies evaluate the rates of ventricular catheter (VC) misplacement and postoperative intracerebral hemorrhage (ICH) after surgery. In this study, we evaluated rate VC ICH in hydrocephalus patients. A consecutive series adult patients (n = 240) that received for were included study. Misplacement was defined as tip located contralateral ventricle or intraparenchymal. The event based on verification...

Summary Sleepiness and apathy are often reported in patients with normal pressure hydrocephalus. However, research on outcomes after shunt surgery has mainly focused the classical triad symptoms, that is, gait, cognition, bladder dysfunction. This study aimed to describe effects of treatment excessive daytime sleepiness whether there was a relation changes ventricular volume. Pre‐ postsurgical investigated using Epworth scale sample 32 hydrocephalus who underwent surgery. Data were gathered...

Communicating hydrocephalus is caused by an accumulation of cerebrospinal fluid (CSF) that often treated with a ventricular shunt. There are few studies on the rates catheter (VC) misplacement and postoperative intracerebral hemorrhage (ICH) after shunt surgery. In this study, we evaluated rate VC ICH addition, was correlated to revision within six months, respectively.

The surgical approach for colloid cysts of the third ventricle mainly consists endoscopic or microscopic but few studies compare neurologic outcomes and complications related to different approaches. We retrospectively reviewed our results after resection using surgery (ES) compared open microsurgery (OS).Fifty-one patients were included in study which 17 underwent ES. Colloid cyst size Evans' index evaluated on CT MRI scans. Presenting symptoms, between two groups analysed Fisher's exact...

Objective Headache is a common symptom among patients with pituitary tumors, as it in the general population. The aim of study was to investigate headache tumors before and 6 months after endoscopic transsphenoidal surgery (TSS). Design This prospective observational cohort study. Setting conducted at university tertiary referral hospital. Participants A total 110 adult underwent TSS for tumors. Main Outcome Measures Migraine Disability Assessment (MIDAS) questionnaire used assessment...