A5050143789- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Hepatitis C virus research
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Prostate Cancer Treatment and Research
- Hemoglobinopathies and Related Disorders
- Neurosurgical Procedures and Complications
- HIV/AIDS drug development and treatment
- Prostate Cancer Diagnosis and Treatment
- Anorectal Disease Treatments and Outcomes
- Organ Transplantation Techniques and Outcomes
- Hepatitis B Virus Studies
- Drug-Induced Hepatotoxicity and Protection
- Pelvic floor disorders treatments
- Renal Transplantation Outcomes and Treatments
- Cardiovascular Issues in Pregnancy
- Cardiac electrophysiology and arrhythmias
- Inflammatory Biomarkers in Disease Prognosis
- Viral Infections and Immunology Research
- Transplantation: Methods and Outcomes
- Aortic Disease and Treatment Approaches
- Mechanical Circulatory Support Devices
- Liver physiology and pathology
- Foot and Ankle Surgery
Affiliated Hospital of Southwest Medical University
2018-2025
Suzhou Municipal Hospital
2021
Nanjing Medical University
2021
National Health and Family Planning Commission
2021
Fudan University
2021
Nanfang Hospital
2021
Hubei University of Chinese Medicine
2021
Wuhan University
2007-2020
Renmin Hospital of Wuhan University
2007-2020
Yangzhou University
2020
Despite evidence for a role prolactin signaling in breast and prostate tumorigenesis, receptor-binding monoclonal antibody has not produced clinical efficacy.Increased serum levels may be biomarker receptor inhibition.Results from the pharmacokinetic pharmacodynamics (PD) studies suggest that inappropriately long dosing intervals insufficient exposure to LFA102 have resulted lack of antitumor efficacy.Based on preclinical data, combination therapy with those novel agents targeting hormonal...
Acute-on-chronic liver failure (ACLF) is the major cause of mortality in patients infected with hepatitis B virus (HBV); however, early determination prognosis HBV-ACLF insensitive or limited. This study aimed to analyze differentially expressed proteins plasma using data-independent acquisition mass spectrometry provide a reference for short-term prognosis. Fifty and 15 healthy controls were enrolled this study. Of these, 10 5 volunteers participated acquisition-based proteomics potential...
Abstract Background Systemic inflammatory response is closely related to the development and prognosis of liver failure. This study aimed establish a new model combing markers including neutrophil/lymphocyte ratio (NLR) red blood cell distribution width (RDW) with several hematological testing indicators assess patients hepatitis B virus-related acute-on-chronic failure (HBV-ACLF). Methods A derivation cohort 421 validation 156 were recruited from three hospitals. Retrospectively collecting...
To investigate the clinical effect of combination therapy with Fufang Biejia Ruangan tablet and entecavir in patients hepatitis B virus (HBV)-related cirrhosis.A total 163 HBV-related cirrhosis were recruited for treatment between March 2010 August 2012, divided into following three groups:group A (n =56) received Tablet plus entecavir; group =52) only; C =55) only. Enzyme-linked immunoassay methods used to measure serum levels hyaluronic acid (HA), laminin (LN), collagen (PCIV) prolyl...
Abstract Background Intrauterine balloon aortic valvuloplasty (IUBAV) has been used for critical stenosis. However, it is necessary to determine the fetal impairments such as preterm birth after this approach and find a way prevent or reduce them. Methods In present study, we evaluated therapeutic value of indomethacin (IDM) dexamethasone (DXS) on reducing rate in experimental goats IUBAV. Results Our results indicated that administration IDM/DXS significantly reduced premature birth....
There remains controversy about whether Brugada syndrome (BS) has structural heart changes. We occasionally noted that a patient with BS had quite unusual regional wall motion abnormality at the basal segment of interventricular septum (IVS) during echocardiographic examination. The unexpected finding promoted us to reexamine our patients by interrogation in present study.Patients (n = 11), complete right bundle branch block (RBBB) and control subjects 11) were enrolled this study....
To establish a model for predicting the short-term prognosis of patients with HBV-related acute-onchronic liver failure (HBV-ACLF) based on red blood cell distribution width (RDW) and end-stage disease (MELD) scores.A total 245 HBV-ACLF were retrospectively analyzed their clinical data results routine hematological tests, function, renal coagulation test, HBV-DNA, other indicators at admission. Univariate analysis binary logistic regression used to test risk factors death patients, MELD-RDW...
Abstract Backgrounds: Systemic inflammatory response is closely related to the development and prognosis of liver failure. This study aimed establish a new model combing markers including neutrophil/lymphocyte ratio (NLR) red blood cell distribution width (RDW) with several hematological testing indicators assess patients hepatitis B virus-related acute-on-chronic failure (HBV-ACLF).Methods: A derivation cohort 421 validation 156 were recruited from three hospitals. Retrospectively...
Objective To investigate the fetal hemodynamic and growth effect, maternal pregnant outcome of indomethacin on goat model intrauterine balloon aortic valvuloplasty(IUBAV). Methods Forty twin goats(106-124 gestational days, term: 150 days) were designed as research objects IUBAV was established.According to whether adopting goat, 40 goats randomly divided into control group(placebo n=20) group(feeding n=20). According administration, 80 sheep then enrolled 4 groups.A1 group: placebo+...