A5066569264- MicroRNA in disease regulation
- Circular RNAs in diseases
- Thyroid and Parathyroid Surgery
- Thyroid Cancer Diagnosis and Treatment
- Airway Management and Intubation Techniques
- Bone Metabolism and Diseases
- Carbon dioxide utilization in catalysis
- Solar Thermal and Photovoltaic Systems
- Catalysis and Oxidation Reactions
- Head and Neck Anomalies
- Catalysis for Biomass Conversion
- Pregnancy-related medical research
- Bone health and treatments
- Sympathectomy and Hyperhidrosis Treatments
- Process Optimization and Integration
- Cancer-related molecular mechanisms research
- Voice and Speech Disorders
- Cancer Diagnosis and Treatment
- Ionic liquids properties and applications
- Telomeres, Telomerase, and Senescence
- Platelet Disorders and Treatments
- Arsenic contamination and mitigation
- Carbon Dioxide Capture Technologies
- Phase Equilibria and Thermodynamics
- Immune Cell Function and Interaction
Sir Run Run Shaw Hospital
2016-2024
Zhejiang University
2016-2024
China University of Petroleum, Beijing
2023
China Academy of Building Research
2023
Henan University
2020
Chinese Academy of Sciences
2020
Institute of Process Engineering
2020
University of Illinois Urbana-Champaign
2013
Shenyang 242 Hospital
1998
Abstract Papillary thyroid cancer (PTC) has a continuously increasing incidence and imposes heavy medical burden to individuals society due its high proportion of lymph node metastasis recurrence in recent years. Circular RNAs, class noncoding participate the progression many cancers, but role circRNAs PTC is still rarely reported. In this study, circRNA deep sequencing was performed identify differentially expressed PTC. CircRUNX1 selected for expression PTC, circRUNX1 silencing directly...
Papillary thyroid cancer (PTC) is a common endocrine tumor with rapidly increasing incidence in recent years. Although the majority of PTCs are relatively indolent and have good prognosis, certain proportion highly aggressive lymphatic metastasis, iodine resistance, easy recurrence. Circular RNAs (circRNAs) class noncoding that linked to variety processes several cancers, including PTC. In current study, circRNA high-throughput sequencing was performed identify alterations expression levels...
Abstract Low back pain, triggered by intervertebral disc degeneration (IVDD), is one of the most common causes disability and financial expenditure worldwide. However, except for surgical interventions, effective medical treatment to prevent progression IVDD lacking. This study aimed investigate effects circKIF18A, a novel circRNA, on explore its underlying mechanism in IVDD. In this study, we found that oxidative stress was positively correlated with nucleus pulposus cell (NPC) senescence...
Osteosarcoma is the most common primary malignant bone tumor in adolescents. While chemotherapy combined with surgery can improve prognosis of some patients, chemo-resistance still a huge obstacle osteosarcoma treatment. Accumulating evidence demonstrates that circular RNAs (circRNAs) are involved cancer progression and metastasis, but their specific role remains mostly undescribed. In this study, we performed circRNA deep sequencing identified 88 distinct circRNAs from human cell lines...
Papillary thyroid cancer (PTC) is an endocrine malignant tumor with a rapidly increasing incidence in recent years. Although the disease prognosis good general, there are still some patients local invasion, distant metastasis and recurrence, which make treatment difficult. This study aimed to investigate effect of novel circRNA, circPCNXL2, on progression PTC explore its underlying mechanism PTC. In this study, we found that expression circPCNXL2 was upregulated PTC, positively correlated...
Enhanced osteoclast formation and function have essential roles during post‑menopausal osteoporosis. A number of cytokines been reported to regulate osteoclastogenesis be involved the pathogenesis However, regulation osteolysis by microRNAs (miRNAs) has remained fully elucidated. The present study used a microarray analysis identify variety miRNAs that are differentially expressed formation. Six down‑regulated miRNAs, miR‑21a‑5p, miR‑27a‑3p, let‑7i‑5p, miR‑22‑3p, miR‑340‑5p miR‑23a‑5p, whose...
Apoptosis of NB4 cells induced by sodium arsenite and arsenate was studied using flow cytometry DNA gel electrophoresis in order to investigate their effects on cell cycle determine the relationship between apoptosis cycle. In this study, we found that: 1) at low doses, selectively G2+M phase after its being arrested G2 phase. With increment blocked phase, dUTP-specifically labeling increased without concomitant dUTP-labeling other two phases cycle; 2) high extensive from all preference...
The development of transoral endoscopic vestibular approach thyroidectomy (TOETVA) has been limited by inherent defects, such as mental nerve injury and carbon dioxide (CO2)-related complications. Herein, we proposed a new technique without CO2 called gasless submental-transoral combined (STET) to solve the problems in TOETVA.We reviewed 75 patients who successfully underwent STET using novel instruments at our institution from November 2020 2021. A main incision approximately 2 cm was made...
Objective: To examine the feasibility of modified gasless trans-subclavian approach endoscopic thyroidectomy for lateral neck dissection (LND) in papillary thyroid carcinoma (PTC). Methods: The clinical data 31 patients with PTC who underwent LND Department Head and Neck Surgery, Run Shaw Hospital, from January to October 2022 were retrospectively analyzed. There 2 males 29 females, aged (32.6±8.3) years (range: 17 55 years). maximum diameter primary lesion (M(IQR)) was 1.06 (1.16) cm 0.53...
Abstract: Endoreplication and maturation of the megakaryocyte (MK) may be retarded or delayed during ontogenesis. In this study, CD 34 + cells were isolated from both human fetal liver adult bone marrow incubated with thrombopoietin (TPO). The cell number, morphological characteristics, platelet‐associated antigen phenotype, stage DNA ploidy 41 examined day 0 to 12 in culture. 1) TPO stimulated proliferation (FL)‐derived a mean 73.14‐fold increase after d Adult BM‐derived increased only...
Natural compounds are alternative agents that have therapeutic potential for preventing and treating osteoporosis. Traditionally, sanguinarine has been used clinically due to its diverse biological properties, including antimicrobial, anti‑inflammatory anticancer effects. Recently, the first time, it was reported inhibits osteoclast differentiation bone resorption by suppressing tumor necrosis factor ligand superfamily member 11‑induced nuclear factor‑κB extracellular signal‑regulated kinase...
Objective: To examine the safety and feasibility of gasless submental-transoral combined appoach endoscopic thyroidectomy for papillary thyroid carcinoma (PTC). Methods: A retrospective analysis clinical data 41 patients with PTC who underwent at Department Head Neck Surgery, Sir Run Shaw Hospital, Zhejiang University School Medicine from November 2020 to April 2021. There were 5 males 36 females age (35.0±8.7) years (range: 19 58 years). horizontal incision a length 2.0 cm is made under...
CO2 reduction is the focus of international attention, and conversion into carbonate an important way to reduce emissions. In this paper, a series novel imidazole-carboxylic acid halogen dual-ionic liquid heterogeneous catalysts were designed synthesized catalyze epoxide cyclic carbonates under mild conditions. The results indicated that as multi-active site catalyst, ([DBUH+][-O2MMIM+][Br-] exhibited best catalytic activity. has advantages reusability, simple preparation absence other...
Abstract Background and Objective: Telomeres play a critical role in maintaining the structural integrity of chromosomes. Short telomeres may lead to chromosomal instability increase cancer risk related death. In this longitudinal study we examined prospective associations between blood leukocyte telomere length (TL) incidence mortality. Methods: Our population included total 791 participants Normative Aging Study (NAS), 1963-established devoted determining health effects aging. Between...