- CRISPR and Genetic Engineering
- DNA Repair Mechanisms
- Genomics and Chromatin Dynamics
- Diagnosis and Treatment of Venous Diseases
- Diabetic Foot Ulcer Assessment and Management
- Pluripotent Stem Cells Research
- Viral Infectious Diseases and Gene Expression in Insects
- Peripheral Artery Disease Management
IFOM
2020
University of Milan
2020
Universidad de Ciencias Empresariales y Sociales
2014
Unrepaired DNA damage during embryonic development can be potentially inherited by a large population of cells. However, the quality control mechanisms that minimize contribution damaged cells to developing embryos remain poorly understood. Here, we uncovered an ATR- and CHK1-mediated transcriptional response replication stress (RS) in mouse stem (ESCs) induces genes expressed totipotent two-cell (2C) stage 2C-like This is mediated Dux, multicopy retrogene defining cleavage-specific program...
Summary Unrepaired DNA damage during embryonic development can be potentially inherited by a large population of cells. However, the quality control mechanisms that minimize contribution damaged cells to developing embryos remain poorly understood. Here, we uncovered an ATR- and CHK1-mediated transcriptional response replication stress (RS) in ESCs induces genes expressed totipotent two-cell (2C) stage 2C-like This is mediated Dux, multicopy retrogene defining cleavage-specific program...
Si bien el concepto de angiosoma se introdujo a partir los estudios Taylor y Palmer en 1987 para prolongar la sobrevida injertos cirugía plástica, no fue hasta 2001 que describieron seis angiosomas del pie comenzaron utilizarse reperfusión úlceras diabético. Actualmente pone mayor énfasis posible utilidad revascularización directa correspondiente al territorio úlcera pacientes con diabético fin aumentar velocidad las tasas curación mismas. El objetivo esta revisión es definir angiosoma,...