A5100743247- Gut microbiota and health
- Heme Oxygenase-1 and Carbon Monoxide
- Nanocluster Synthesis and Applications
- Nerve injury and regeneration
- Reproductive Health and Technologies
- Assisted Reproductive Technology and Twin Pregnancy
- Cytomegalovirus and herpesvirus research
- Tissue Engineering and Regenerative Medicine
- Immune Cell Function and Interaction
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Diet and metabolism studies
- Probiotics and Fermented Foods
- Sperm and Testicular Function
- Retinoids in leukemia and cellular processes
- Autophagy in Disease and Therapy
- Advanced Nanomaterials in Catalysis
- Extracellular vesicles in disease
- MicroRNA in disease regulation
- NF-κB Signaling Pathways
- Dietary Effects on Health
- Nanoplatforms for cancer theranostics
- Mesenchymal stem cell research
- Cancer Research and Treatments
- interferon and immune responses
- Bacillus and Francisella bacterial research
Guangxi University
2020-2024
Guangxi Medical University
2021-2024
Introduction Recent evidence supports a role for the gut microbe-metabolites in longevity. However, phenomenon of hypertension is more common longevity area and whether associated with remains unclear. Here, we hypothesize that levels microbiota, SCFAs, urine metabolites were different between elderly Methods We recruited 46 volunteers from Donglan County, Guangxi, 32 selected included experiment. The subjects divided into two groups according to age, Hypertension Elderly (HTE, aged 70.5 ±...
Salmonella enterica serovar Typhimurium (S. Typhimurium), a foodborne pathogen that poses significant public health risks to humans and animals, presents formidable challenge due its antibiotic resistance. This study explores the potential of Lactobacillus acidophilus (L. 1.3251) probiotics as an alternative strategy combat resistance associated with S. infection. In this investigation, twenty-four BALB/c mice were assigned four groups: non-infected, non-treated group (CNG); infected, (CPG);...
In this study, we explored the growing use of metal-organic framework (MOF)-based Nanozymes in biomedical research, with a specific emphasis on their applications stroke therapy. We have discussed complex nature pathophysiology, highlighting crucial role reactive oxygen species (ROS), and acknowledging limitations natural enzymes addressing these challenges. also nanozymes, particularly those based MOFs, structural similarities to enzymes, potential improve reactivity various applications....
Parkinson's disease (PD) is a degenerative disorder of the nervous system characterized by loss dopaminergic neurons and damage in substantia nigra (SN) striatum, resulting impaired motor functions. This study aims to investigate how extracellular vesicles (EVs) derived from human umbilical cord mesenchymal stem cells (HucMSC) regulate Special AT-rich sequence-binding protein-1 (SATB 1) influence Wnt/β-catenin pathway autophagy PD model. The model was induced damaging SH-SY5Y mice using...
Introduction: After spinal cord injury (SCI) occurs, the lesion is in a growth inhibitory microenvironment that severely hinders neural regeneration. In this microenvironment, factors are predominant and promote nerve regeneration few. Improving neurotrophic key to treating SCI. Methods: Based on cell sheet technology, we designed bioactive material with cord‐like structure –SHED induced homogenate protein of (hp–SHED sheet). Hp–SHED was implanted into for SCI rats SHED suspensions as...
Aresenic trioxide (ATO) is proven to be active against leukaemia cells by inducing apoptosis and differentiation. Even though ATO could effectively induce remissions of cells, the drug resistance was observed occasionally. To further dissect mechanism resistance, we selected ATO-resistant SH-SY5Y found that Bcl-2 controlled sensitivity in cells. We report necroptosis, autophagy, NF-ƘB MAPK signalling pathway are not involved ATO-induced apoptosis. Moreover, showed distinct mitochondrial...
The aim was to investigate the influences of different sperm sources on clinical outcome and neonatal patients with intracytoplasmic injection. We retrospectively analysed who underwent injection in our reproductive centre from 2011 2020. screened data assisted outcomes four groups sources: testicular sperm, epididymal ejaculated donor for analysis divided non-ejaculated group explore their impact outcomes. A total 2139 cycles were involved this study. There significant differences...