- Sarcoidosis and Beryllium Toxicity Research
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac Structural Anomalies and Repair
- Computer Graphics and Visualization Techniques
- Cardiovascular Function and Risk Factors
- 3D Shape Modeling and Analysis
- Mechanical Circulatory Support Devices
- Diabetes Management and Research
- Viral-associated cancers and disorders
- Cancer, Hypoxia, and Metabolism
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Pain Management and Treatment
- Advanced Vision and Imaging
- Cardiac pacing and defibrillation studies
- Heart Failure Treatment and Management
- Parathyroid Disorders and Treatments
- Cancer Treatment and Pharmacology
- Renal function and acid-base balance
- Chemotherapy-induced cardiotoxicity and mitigation
- X-ray Diffraction in Crystallography
- Potassium and Related Disorders
- Blood groups and transfusion
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
Hokkaido University Hospital
2020-2025
Hokkaido Research Organization
2025
Hokkaido University
1994-2024
Cardiovascular Center Hokkaido Ohno Hospital
2022-2023
Saitama Medical University Hospital
2023
Tohoku University
2023
Yamanashi Prefectural Central Hospital
2022
Saitama Medical University
2012-2022
University of Hawaiʻi at Mānoa
2022
University of Hawaii System
2022
The width of crystal lattice plane spacing (d-spacing) distribution related to microscopic-strain and crystallite size in a martensite phase 2 cm thick quenched-ferritic steel sample was quantitatively mapped real space by Bragg-edge broadening analysis spectral data from pulsed neutron transmission experiment. This performed under the condition that instrumental resolution parameters, determined ferrite same without effects, were unchanged over area, assuming d-spacing distributed according...
Adhesion G-protein coupled receptor F5 (ADGRF5) was recently identified as an essential regulator of pulmonary surfactant homeostasis in alveolar type II cells. We previously showed that addition to abnormal accumulation, Adgrf5-deficient (Adgrf5-/-) mice exhibit emphysema-like signs, suggesting a possible role for ADGRF5 immune regulation. Here, we extended the phenotypic analysis Adgrf5-/- help understand its biological lung, and especially regulation.Histological features lungs were...
We prepared a 6-O-desulfated (DS-) heparin (Hep) hydrogel as an excellent carrier for the controlled release of Hep-binding growth factors, such fibroblast factor (FGF)-2. This material, which is partially derived from photoreactive groups, cinnamate, easily crosslinked upon ultraviolet light (UV)-irradiation, resulting in water-insoluble, viscous, and injectable hydrogel. In present study, we examined capacity 6-O-DS-Hep to immobilize FGF-2, well FGF-2 molecules this vitro vivo. Only 10%...
Summary Multicentric Castleman disease–thrombocytopenia, anasarca, reticulin fibrosis of bone marrow, renal dysfunction and organomegaly (MCD‐TAFRO)—is an emergent phenotype characterized by lymphoproliferation, fluid collection, hemocytopenia multiple organopathy. Although studies have demonstrated aberrant blood cytokine/chemokine profile referred to as “chemokine storm”, the pathogenesis remains unclear. We aimed identify pathogenic key molecules, potential diagnostic targets therapeutic...
Abstract Background Sarcoidosis is a systemic granulomatous disease that affects multiple organs. Cardiac involvement key determinant of poor clinical outcomes in the patients with sarcoidosis, as it causes congestive heart failure, conduction abnormalities, ventricular tachycardia and fibrillation (VT/VF), sudden cardiac death (SCD). Although implantable cardioverter defibrillators (ICDs) are used to prevent SCD from VT/VF sarcoidosis (CS), generalizability AHA/ACC/HRS guidelines for...
Epirubicin-based chemotherapy carries a risk of inducing heart failure, although the frequency is rare. Bevacizumab, an anti-vascular endothelial growth factor monoclonal antibody, has recently been widely used in patients with recurrent breast cancer as first-line chemotherapeutic agent. Heart failure or arterial thromboembolism reported rare cardiovascular complication bevacizumab. We herein report patient reversible therapeutics-related cardiac dysfunction associated bevacizumab and...
In a cel animation workplace, nonphotorealistic rendering techniques are often applied to 3D scene model, which is constructed by referring the 2D hand-drawn images of scene. There exist lot features that must be modeled from information. The accentuation effects amongst most important in this context, refers adding shading specific region an artist wishes viewer observe drawn brighter than other regions. paper, method proposed for extraction single painted image animated This enables...