A5025863083- Systemic Lupus Erythematosus Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Rheumatoid Arthritis Research and Therapies
- Platelet Disorders and Treatments
- Eosinophilic Disorders and Syndromes
- Peripheral Neuropathies and Disorders
- Systemic Sclerosis and Related Diseases
- Venous Thromboembolism Diagnosis and Management
- Pulmonary Hypertension Research and Treatments
- Immunodeficiency and Autoimmune Disorders
- Drug-Induced Ocular Toxicity
- Renal Diseases and Glomerulopathies
- Viral-associated cancers and disorders
- Toxin Mechanisms and Immunotoxins
- Congenital Ear and Nasal Anomalies
Japanese Red Cross Hokkaido College of Nursing
2025
Hokkaido University
2021-2024
Pulmonary hypertension (PH) is the leading cause of death among patients with systemic sclerosis (SSc). Recently, early therapeutic intervention to improve prognosis was suggested, and definition PH recently revised by lowering cut-off value mean pulmonary arterial pressure (mPAP) from ≥ 25 > 20 mmHg. However, optimal threshold for remains unclear. We aim evaluate SSc its relationship mPAP. For this non-interventional retrospective prospective cohort study, we enrolled or scleroderma...
ABSTRACT Objectives Hydroxychloroquine (HCQ) is recommended at a target dose of 5 mg/kg per actual body weight to reduce the risk retinopathy in systemic lupus erythematosus (SLE). However, efficacy HCQ has been established doses 6.5 ideal weight. This study aimed clarify effects on continuation rate Japanese patients, who generally have lower mass index than Western patients. Methods retrospective single-centre observational enrolled patients with SLE therapy. Patients were divided into two...
Summary Multicentric Castleman disease–thrombocytopenia, anasarca, reticulin fibrosis of bone marrow, renal dysfunction and organomegaly (MCD‐TAFRO)—is an emergent phenotype characterized by lymphoproliferation, fluid collection, hemocytopenia multiple organopathy. Although studies have demonstrated aberrant blood cytokine/chemokine profile referred to as “chemokine storm”, the pathogenesis remains unclear. We aimed identify pathogenic key molecules, potential diagnostic targets therapeutic...