Background and Purpose: Motor impairment is a common occurrence in patients with acute basal ganglia (BG) ischemic stroke (ABGIS). However, the underlying mechanisms of poststroke motor dysfunction remain incompletely elucidated. In this study, we employed multifrequency band wavelet transform-based amplitude low-frequency fluctuations (Wavelet-ALFFs) to investigate alterations spontaneous regional neural activity ABGIS. Methods: A total 39 ABGIS 45 healthy controls (HCs) underwent...

<i>Background:</i> Secondary degeneration following supratentorial stroke has been detected by some studies using diffusion tensor imaging (DTI), but the anterograde and retrograde in pyramidal tract after pontine infarction its potential clinical significance are not well understood. <i>Methods:</i> Fourteen patients with a recent infarct underwent three DTIs at week 1, 4, 12 onset. age- gender-matched controls DTI once. Mean diffusivity fractional anisotropy (FA)...

To investigate the effects of transplantation into rats with stroke bone marrow-derived mesenchymal stem cells (MSCs) induced by brain-derived neurotrophic factor (BDNF).MSCs were harvested from 6-week-old Sprague-Dawley male rats, and transplanted adult transient middle cerebral artery occlusion. At 48 hours after stroke, weighing 250-280 g, injected via tail vein 1×10(7) MSCs or BDNF (BDNF-MSCs) suspended in 1 ml phosphate-buffered saline. All animals underwent neurological function test...

The present study aimed to identify the characteristics, predictors, and imaging features of poor recovery in cases cerebral venous sinus thrombosis (CVST).A total 290 consecutive adult patients with CVST were enrolled from January 2017 December 2021 five hospitals Nanning, Guangxi. According modified Rankin scale (mRS) score at hospital discharge, classified into good prognosis (GP, mRS ≤2) groups (PP, mRS>2) groups. Logistic regression was used factors associated clinical outcomes.Of...

Objective. The purpose of this study was to investigate the characteristics different frequency bands in spontaneous brain activity among patients with acute basal ganglia ischemic stroke (BGIS). Methods. In present study, thirty-four BGIS and forty-four healthy controls were examined by resting-state functional magnetic resonance imaging (rs-fMRI) from May 2019 December 2020. Two amplitude methods including low-frequency fluctuations (ALFF) fractional ALFF (fALFF) calculated three...

The effectiveness of endovascular treatment (EVT) in patients with mild stroke (National Institutes Health Stroke Scale score ≤5) and acute anterior circulation large vessel occlusion (AACLVO) remains unknown.To conduct a meta-analysis to compare the efficacy safety EVT AACLVO.EMBASE, Cochrane Library, PubMed, Clinicaltrials.gov databases were searched until October 2022. Both retrospective prospective studies which compared clinical outcomes between medical included. ORs 95% confidence...

Background. Wallerian degeneration in pyramidal tract following supratentorial stroke has been detected by some studies using diffusion tensor imaging (DTI), but the middle cerebellar peduncle after pontine infarction and its potential clinical significance remain to be confirmed. Methods. Seventeen patients with a recent focal infarct underwent 3 DTIs at week 1 (W1), 4 (W4), 12 (W12) onset. age-matched gender-matched controls DTI one time. Mean diffusivity fractional anisotropy (FA) were...

Objective To identify the unique clinical features and biological markers of lung cancer-associated stroke. Methods We recruited 102 patients with cancer plus stroke, cancer, Detailed information was analysed compared among groups. Results The groups were age-matched. Patients stroke showed multiple lesions involving cerebral artery territories on magnetic resonance imaging, stroke-alone patients. These also had a poorer modified Rankin Scale score at 30 days, high mortality (18.6%). higher...

BACKGROUND:The combined effects of bilateral corticospinal tract (CST) reorganization and interhemispheric functional connectivity (FC) on motor recovery upper lower limbs after stroke remain unknown. MATERIAL AND METHODS:A total 34 patients underwent magnetic resonance imaging (MRI) examination at weeks 1, 4, 12 stroke, with a control group healthy subjects receiving 1 MRI examination. Interhemispheric FC in the somatomotor network (SMN) was calculated using resting-state (rs-fMRI)....

Purpose. Several functional magnetic resonance imaging (fMRI) studies have investigated the resting-state connectivity (rs-FC) changes in primary motor cortex (M1) patients with acute basal ganglia ischemic stroke (BGIS). However, frequency-specific FC of M1 BGIS are still unclear. Our study was aimed at exploring altered three frequency bands and potential features as biomarkers for identification by using a support vector machine (SVM). Methods. We included 28 42 healthy controls (HCs)....

The purpose of this research was to explore the underlying biological processes causing coronavirus disease 2019- (COVID-19-) related stroke. Gene Expression Omnibus (GEO) database utilized obtain four COVID-19 datasets and two stroke datasets. Thereafter, we identified key modules via weighted gene co-expression network analysis, following which COVID-19- stroke-related crucial were crossed identify common genes COVID-19-related intersected with hub screened Cytoscape software discover...

Background. Tongxinluo is a traditional Chinese medicine compound with the potential to promote neuronal functional recovery in cerebral ischemic infarction. Objective. This study aimed disclose whether tongxinluo promotes neurological and neurogenesis angiogenesis infarcted area SVZ after infarction hypertensive rats. Methods. The model was prepared by distal middle artery occlusion (MCAO) administrated 24 h MCAO lasted for 3, 7, or 14 days. Behavioral tests were performed evaluate...

There have been only a few studies of ischemic stroke in patients with pulmonary tuberculosis (pTB). This study aimed to explore the clinical features and underlying pathogenesis tuberculosis-related (TBRIS).Active acute (without conventional vascular risk factors) were recruited as TBRIS group. Patients who solely had active control group (pTB group). Clinical data collected, multiple logistic regression analysis was applied analyze independent factors for TBRIS.A total 179 pTB enrolled....

The aim of this study was to investigate the spontaneous regional neural activity abnormalities in patients with acute basal ganglia ischemic stroke (BGIS) using a multifrequency bands homogeneity (ReHo) method and explore whether alteration ReHo values associated clinical characteristics.In study, 34 BGIS 44 healthy controls (HCs) were recruited. All participants examined by resting-state functional magnetic resonance imaging (rs-fMRI). used detect alterations activities BGIS. A two-sample...

To investigate the hypercoagulability of hepatocellular carcinoma (HCC)-related cerebral infarction (HCRCI) with thromboelastography (TEG).A multicenter prospective study was conducted in HCRCI patients, HCC patients without infarction, and acute (ACI) between January 2016 December 2019. TEG parameters laboratory clinical data were collected compared among three groups. confirm independent risk factors HCRCI, multivariate analyses conducted. Receiver operating characteristic (ROC) curves...

<h3>Objective</h3> To assess the risk of glucose-6-phosphate dehydrogenase (G6PD) on stroke prognosis, we compared outcomes between patients with and without G6PD deficiency. <h3>Methods</h3> The study recruited 1,251 acute ischemic stroke. Patients were individually categorized into G6PD-deficiency non-G6PD-deficiency groups according to activity upon admission. primary endpoint was poor outcome at 3 months defined by a modified Rankin Scale (mRS) score ≥2 (including disability death)....

Background: Early neurological deterioration (END) after bridging therapy (BT) of acute ischemic stroke (AIS) patients is associated with poor outcomes. Objective: We aimed to study the incidence, risk factors and prognosis END BT. Methods: From January December 2021, clinical data AIS treated by BT (intravenous thrombolysis alteplase prior mechanical thrombectomy) from three comprehensive centers were analyzed. Patients divided into non-END group according whether they developed within 72...

Abstract Background Cerebrovascular complications are severe events following orthotopic liver transplantation (OLT). This study aimed to observe the clinical and neuroimaging features possible risk factors of in-hospital cerebrovascular in patients who underwent OLT. Patients methods We retrospectively reviewed 337 consecutive 358 OLTs. were determined by manifestations, analyzed with intracranial hemorrhage. Results Ten (3.0%) developed (8 cases experienced hemorrhage 2 had cerebral...