Hui Cai

ORCID: 0000-0002-6182-966X
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About
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Research Areas
  • Antioxidant Activity and Oxidative Stress
  • Gastric Cancer Management and Outcomes
  • Cancer-related molecular mechanisms research
  • Ferroptosis and cancer prognosis
  • Cancer, Lipids, and Metabolism
  • Cancer Immunotherapy and Biomarkers
  • RNA modifications and cancer
  • Nutritional Studies and Diet
  • Immune Cell Function and Interaction
  • Liver Disease Diagnosis and Treatment
  • Colorectal Cancer Surgical Treatments
  • Pancreatic and Hepatic Oncology Research
  • Inflammatory Biomarkers in Disease Prognosis
  • Epigenetics and DNA Methylation
  • Circular RNAs in diseases
  • Metabolism, Diabetes, and Cancer
  • Colorectal Cancer Screening and Detection
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Enhanced Recovery After Surgery
  • Genetic factors in colorectal cancer
  • Colorectal Cancer Treatments and Studies
  • Obesity, Physical Activity, Diet
  • Helicobacter pylori-related gastroenterology studies
  • Metastasis and carcinoma case studies
  • Cancer Mechanisms and Therapy

Vanderbilt University Medical Center
2008-2025

First Affiliated Hospital Zhejiang University
2025

Gansu Provincial Hospital
2013-2024

Ningxia Medical University
2023-2024

Lanzhou University
2013-2024

Second Military Medical University
2013-2024

Sun Yat-sen University
2019-2024

Institute for Clinical Evaluative Sciences
2024

University of California, Los Angeles
2024

Cedars-Sinai Smidt Heart Institute
2024

This study aims to analyse the current demand by senior citizens in Lanzhou, China for a combination of medical and elderly care services identify factors influencing their needs.

10.1186/s12877-020-01616-6 article EN cc-by BMC Geriatrics 2020-09-09

Abstract Background Circulating soluble programmed death ligand 1 (sPD-L1) can negatively regulate T-cell function and serve as a prognostic or predictive marker in variety of cancers. However, rare studies have evaluated the potential roles sPD-L1, no study has estimated its value for efficacy immune treatment colorectal cancer (CRC). Methods Plasma samples from 192 CRC patients were used to estimate correlations between clinicopathological features secreted PD-L1 (secPD-L1) exosomal...

10.1186/s12967-023-03879-0 article EN cc-by Journal of Translational Medicine 2023-01-13

BACKGROUND Gastric cancer has a high incidence and fatality rate, surgery is the preferred course of treatment. Nonetheless, patient survival rates are still low, major postoperative complications cannot be disregarded. The systemic inflammatory response, nutritional level, coagulation status key factors affecting recovery prognosis gastric patients. response index (SIRI) albumin fibrinogen ratio (AFR) two valuable comprehensive indicators severity inflammation in various medical conditions....

10.4251/wjgo.v16.i3.732 article EN World Journal of Gastrointestinal Oncology 2024-03-12

Abstract Background The family history of gastric cancer holds important implications for surveillance and prevention, yet existing evidence predominantly comes from case–control studies. We aimed to investigate the association between risk overall by various subtypes in Asians a prospective study. Methods included 12 cohorts with 550,508 participants Asia Cohort Consortium. Cox proportional hazard regression was used estimate study-specific adjusted ratios (HRs) 95% confidence intervals...

10.1007/s10120-024-01499-1 article EN cc-by Gastric Cancer 2024-04-22

Objective To study the association of educational level and risk death from all causes, cardiovascular disease (CVD) cancer among Asian populations. Design A pooled analysis 15 population-based cohort studies. Setting participants 694 434 individuals prospective cohorts within Asia Cohort Consortium. Interventions None. Main outcome measures HRs 95% CIs for all-cause mortality, as well CVD-specific mortality cancer-specific mortality. Results total (mean age at baseline=53.2 years) were...

10.1136/bmjopen-2018-026225 article EN cc-by-nc BMJ Open 2019-08-01

<h3>Importance</h3> The association of weight gain from early to middle adulthood with disease risk has not been adequately studied. <h3>Objective</h3> To investigate the adult major health outcomes in a Chinese population low body adulthood. <h3>Design, Setting, and Participants</h3> This population-based cohort study assessed data 48 377 women 35 989 men aged 40 59 years at recruitment 2 prospective studies China. Shanghai Women’s Health Study recruited 74 941 women, 70 years, January 1,...

10.1001/jamanetworkopen.2019.17371 article EN cc-by-nc-nd JAMA Network Open 2019-12-13

Abstract Given the female predominance of thyroid cancer (TC), particularly in reproductive age range, sex hormones have been proposed as an aetiology; however, previous epidemiological studies shown conflicting results. We conducted a pooled analysis using individual data from 9 prospective cohorts Asia Cohort Consortium, to explore association between 10 and hormonal factors TC risk. Using Cox proportional hazards models, cohort-specific hazard ratios (HRs) 95% confidence intervals (CIs)...

10.1158/1940-6207.capr-24-0330 article EN Cancer Prevention Research 2025-01-23

&lt;p&gt;Supplementary Figure 7: Forest plot of stratified analyses between reproductive factors and thyroid cancer risk by body mass index (BMI) smoking status in the Asia Cohort Consortium. The Pooled Hazard Ratios (HRs) with 95% Confidence intervals (CIs) were generated combining cohort-specific HRs. Models for adjusted alcohol drinking BMI those status. a Significant (p-value &lt;0.05). b &lt;0.05) interaction indicating modifying effect on association factor risk. c model included all 9...

10.1158/1940-6207.28703940 preprint EN 2025-04-01

&lt;p&gt;Supplementary Figure 3: Forest plots of the pooled hazard ratios (HRs) and 95% confidence intervals (CIs) generated by combining cohort-specific HRs for association between reproductive factors overall risk thyroid cancer in Asia Cohort Consortium. A - plot CIs breastfeeding status risk, B postmenopausal C age at menopause overall&lt;/p&gt;

10.1158/1940-6207.28703955 preprint EN cc-by 2025-04-01

&lt;p&gt;Supplementary Figure 5: Forest plot of stratified analysis between number children/deliveries and thyroid cancer risk by birth years in the Asia Cohort Consortium. The Pooled Hazard Ratios (HRs) with 95% Confidence intervals (CIs) were generated combining cohort-specific HRs. Models adjusted for smoking status, alcohol drinking status Body mass index. a Significant (p-value &lt;0.05) trend across categories reproductive factor. b interaction indicating modifying effect on...

10.1158/1940-6207.28703949 preprint EN cc-by 2025-04-01
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