A5101797831- Child and Animal Learning Development
- Mental Health Research Topics
- Child and Adolescent Psychosocial and Emotional Development
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Total Knee Arthroplasty Outcomes
- Media Influence and Health
- Immunotherapy and Immune Responses
- Extracellular vesicles in disease
- Digital Mental Health Interventions
- Liver Disease and Transplantation
- Science Education and Pedagogy
- Congenital Anomalies and Fetal Surgery
- Phagocytosis and Immune Regulation
- Organ Transplantation Techniques and Outcomes
- Autophagy in Disease and Therapy
- Infant Development and Preterm Care
- Memory Processes and Influences
- Sport and Mega-Event Impacts
- Vibrio bacteria research studies
- Immune cells in cancer
- Heme Oxygenase-1 and Carbon Monoxide
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Stress Responses and Cortisol
- Single-cell and spatial transcriptomics
- Folklore, Mythology, and Literature Studies
Newcastle University
2015-2017
Washington University in St. Louis
2009-2016
Missouri State University
1982-2009
Texas Tech University
1979
What's in a drop of blood? Blood contains many types cells, including immune system components. Immune cells used to be characterized by marker-based assays, but now classification relies on the genes that express. Villani et al. deep sequencing at single-cell level and unbiased clustering define six dendritic cell four monocyte populations. This refined analysis has identified, among others, previously unknown population potently activates T cells. Further culture revealed possible...
The use of unreliable measures constitutes a threat to our understanding psychopathology, because advancement science using both behavioral and biologically oriented can only be certain if such measurements are reliable. Two pillars the National Institute Mental Health's portfolio-the Research Domain Criteria (RDoC) initiative for psychopathology target engagement in clinical trials-cannot succeed without that possess high reliability necessary tests involving mediation selection based on...
Preschool children were trained in 1 of 3 different types fantasy activities over a school year. The effects this training evaluated variety tasks measuring cognitive development and impulse control. same basic experiment was replicated years. Results indicated that physical enactment experiences (viz., acting fairy tales or enacting previous experiences) had sizable effect on many these variables; while simply listening discussing often no more effective than the control condition merely...
This feasibility study assessed perceived acceptability, adherence rates, and reasons for nonadherence to smartphone-based ecological momentary assessment (EMA). At two sites, participants (n = 103) ages 65 years or older with diagnosed anxiety depressive disorder cognitive concerns responded three times daily EMA questions assessing clinical outcomes 10-day periods. Quantitative qualitative measures followed both Overall, 76% of completed surveys on ≥ 10 the 20 days, 70% at least 30% total...
Abstract Total knee arthroplasty (TKA) is one of the most successful orthopaedic procedures that alleviates pain and restores function in patients with degenerative joint diseases. Arthrofibrosis, abnormal scarring which dense fibrous tissue prevents normal range motion, develops ~3–10% TKA patients. No prophylactic intervention available treatment restricted to aggressive physiotherapy or revision surgery. Tissue was collected from undergoing primary (n = 30) 27) TKA. Revision were...
Elevated cortisol in stress and aging, such as has been seen late-life anxiety disorders, is postulated to accelerate cognitive physiological decline this large increasing population. Selective serotonin-reuptake inhibitors (SSRIs) cognitive-behavioral therapy (CBT) are both effective treatments for generalized disorder (GAD) older adults. On the other hand, there very little research examining effect of combining these therapies on peak levels. For current analyses, we examined...
Abstract Arthrofibrosis is a fibroproliferative disease characterised by excessive deposition of extracellular matrix components intra-articularly leading to pain and restricted range movement. Although frequently observed following total knee arthroplasty (TKA) no therapeutic options exist. A pilot study demonstrated that intra-articular injection Anakinra, an IL-1R antagonist, improved movement in patients with arthrofibrosis however the mechanism action unknown. We hypothesise IL-1α/β...
As science and technology become more sophisticated with the rapid computation capabilities of modern computer available, it becomes both possible economically feasible to scientifically study man his interaction working environment. It is now for a person seeking employment expect obtain position which will not be unnecessarily hazardous immediate health or have detrimental effects over long run. Manual materials handling contributor 400,000 back injuries suffered in U.S. each year. This...
The Devereux Early Childhood Assessment (DECA) was developed to assess the social-emotional functioning of preschool children. developers DECA report initial validity and reliability evidence in support use instrument with 2- 5-year-old children across United States. There is further need collect independent for its intended uses. data collected from parents teachers 780 kindergarten students (age 5.0 5.11) a rural Midwestern area States were analyzed. resulting internal consistency,...
SALTZ, ELI; DIXON, DAVID; KLEIN, STEPHANIE; and BECKER, GLADYS. Studies of Natural Language Concepts. III. Concept Overdiscrimination in Comprehension between Two Four Years Age. CHILD DEVELOPMENT, 1977, 48, 1682-1685. Young children's comprehension natural language concepts was examined by having 2and 4-year-olds select pictorial instances 5 concrete semantic concepts. The results showed that the 2-year-olds were less likely than to consider as exemplars concepts, especially if peripheral...
DIXON, DAVID, and SALTZ, ELI. The Role of Imagery in Concept Acquisition Lower-SES Children. CHILD DEVELOPMENT, 1977, 48, 288-291. present study examined 2 related issues: (a) Do lower-SES children have a representational deficit such that they difficulty concept learning unless the stimulus materials are high imagery value? (b) Does nature to be learned determine optimal type materials? Firstand third-grade perceptual functional concepts with stimuli either or low value (line drawings...