A5088966157- Child and Adolescent Psychosocial and Emotional Development
- Maternal Mental Health During Pregnancy and Postpartum
- Attention Deficit Hyperactivity Disorder
- Bipolar Disorder and Treatment
- Early Childhood Education and Development
- Pneumocystis jirovecii pneumonia detection and treatment
- Digital Mental Health Interventions
- Adolescent and Pediatric Healthcare
- COVID-19 and Mental Health
- Plant Virus Research Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Mosquito-borne diseases and control
- Mental Health Research Topics
- Virology and Viral Diseases
National Institute of Mental Health
2019-2024
National Institutes of Health
2019-2024
Hinge Health
2020
National Center for Infectious Diseases
2003
Ministry of Health
2003
Centers for Disease Control and Prevention
2003
Johns Hopkins Medicine
2000
Johns Hopkins University
2000
University of Pittsburgh
2000
The vesicular stomatitis virus (VSV) G protein is a model transmembrane glycoprotein that has been extensively used to study the exocytotic pathway. A signal in cytoplasmic tail of VSV (DxE or Asp-x-Glu, where x any amino acid) was recently proposed mediate efficient export from endoplasmic reticulum (ER). In this study, we show DxE motif only partially accounts for ER exit G. We have identified six-amino-acid signal, which includes previously Asp and Glu residues, required ER. This...
Introduction Irritability is defined as a tendency towards anger in response to frustration. Clinically, impairing irritability significant public health problem. There need for mechanism-based psychotherapies targeting severe it manifests the context of disruptive mood dysregulation disorder (DMDD). This study protocol describes randomised multiple baseline design testing preliminary efficacy new treatment, exposure-based cognitive-behavioral therapy youth, which also integrates components...
Nasopharyngeal swabs were taken from 906 Malawian children <5 years old visiting rural health clinics. Pneumococcal colonization was high, 84% among all children, and occurred early, 65% of it in <3 months old. Among pneumococcal isolates 46% nonsusceptible to trimethoprim-sulfamethoxazole, 21% penicillin. Trimethoprim-sulfamethoxazole use the previous month a risk factor for trimethoprim-sulfamethoxazole penicillin nonsusceptibility. Forty-three percent serotypes included 7-valent conjugate...
Abstract Enhancing screening practices and developing scalable diagnostic tools are imperative in response to the increasing prevalence of youth mental health challenges. Structured lay psychiatric interviews have emerged as one such promising tool. However, there remains limited research evaluating structured interviews, specifically their characterization internalizing disorders treatment-seeking youth. This study evaluates relationship between Development Well-Being Assessment (DAWBA), a...
Abstract Background Generalised anxiety disorder (GAD) is a chronic and disabling condition with considerable personal economic impact. Cognitive behavioural therapy (CBT) recommended psychological for GAD; however, there are substantial barriers to accessing treatment. Digital CBT, in particular smartphone-delivered has the potential improve accessibility increase dissemination of CBT. Despite emerging evidence smartphone-based interventions reducing anxiety, effect size scores typically...
Background Family history of depression (FHD) is a known risk factor for the new onset depression. However, it unclear if FHD clinically useful prognosis in adolescents with current, ongoing, or past This preregistered study uses longitudinal, multi‐informant design to examine whether child’s adds information about future depressive episodes and severity applying state‐of‐the‐art predictive out‐of‐sample methodology. Methods We examined data current (age 11–17 years) from National Institute...