Saut Horas Hatoguan Nababan

ORCID: 0000-0003-3384-6267
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Liver Disease and Transplantation
  • Hepatitis C virus research
  • Hepatitis B Virus Studies
  • Organ Transplantation Techniques and Outcomes
  • Peroxisome Proliferator-Activated Receptors
  • Diet and metabolism studies
  • Gut microbiota and health
  • Gastroesophageal reflux and treatments
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Hepatitis Viruses Studies and Epidemiology
  • Neuroendocrine Tumor Research Advances
  • Metabolism, Diabetes, and Cancer
  • Systemic Lupus Erythematosus Research
  • Pharmacovigilance and Adverse Drug Reactions
  • Healthcare and Venom Research
  • Drug-Induced Adverse Reactions
  • Intramuscular injections and effects
  • COVID-19 Clinical Research Studies
  • Cancer, Lipids, and Metabolism
  • Alcohol Consumption and Health Effects
  • Cancer, Hypoxia, and Metabolism
  • Liver Diseases and Immunity

Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo
2018-2024

University of Indonesia
2018-2024

Kobe University
2017

Abstract Portal hypertension (PH) poses significant challenges. This paper presents an innovative study on the utilization of endoscopic ultrasound (EUS) for both diagnosis and management PH. Conducted at Dr. Cipto Mangunkusumo National General Hospital in Jakarta, this retrospective case series included patients diagnosed with PH through clinical examination, imaging evaluation, esophagogastroduodenoscopy. Exclusion criteria comprised a history reduced blood consumption within last 5 days,...

10.1002/poh2.74 article EN cc-by-nc-nd Portal hypertension & cirrhosis 2024-02-09

Abstract Background Liver cirrhosis is the final stage of chronic liver disease. Complications due to progression disease may deteriorate function and worsen prognosis. Previous studies have shown that patients with are at increased risk death within 90-day after hospitalization. It necessary identify who higher early mortality. This study aims develop a scoring system predict mortality among hospitalized could be used for modification treatment plan according scores been obtained. By using...

10.1186/s12876-023-02813-4 article EN cc-by BMC Gastroenterology 2023-06-01

Bleeding esophageal varices (BEV) is a serious clinical condition and can potentially be life-threatening. Esophageal are caused by abnormal dilated submucosal collateral veins in the esophagus wall as result of portal hypertension due to liver cirrhosis. Consequently, it important administer appropriate preventive treatment for disease order decrease morbidity mortality rates. The current gold standard identify use esophagogastroduodenoscopy (EGD). However, EGD has limitations its inability...

10.1159/000524529 article EN cc-by-nc Case Reports in Gastroenterology 2022-05-10

Abstract Aim The presence of esophageal collateral veins (ECV) has been reported to be associated with the recurrence varices (EV) and bleeding in liver cirrhotic (LC) patients. This study aimed see potential clinical value deep assessment using endoscopic ultrasound (EUS) patients EV. Methods During 6 months period, a prospective is conducted, where we identified LC who were admitted for esophagogastroduodenoscopy (EGD) screening at Department Internal Medicine, Dr. Cipto Mangunkusumo...

10.1002/poh2.19 article EN cc-by-nc-nd Portal hypertension & cirrhosis 2022-06-01

Gastric varices (GVs) occur in 10-30% of liver cirrhotic patients, with a mortality rate up to 45%. Rupture isolated GVs (IGVs) is less prevalent but often results more severe hemorrhage and higher risk than rupture esophageal (EVs). However, there no clear consensus yet about the optimal management for incidentally discovered IGVs.To determine clinical significance IGVs patients.This was retrospective cohort endoscopy database study within 2-year period (2016-2017). All subjects were...

10.1002/jgh3.12292 article EN cc-by-nc-nd JGH Open 2019-12-28

Background: Non-alcoholic steatohepatitis (NASH) is an expanding cause of chronic liver disease worldwide, including Indonesia, with higher risk progression to cirrhosis and hepatocellular carcinoma. Preclinical experiments using several mice models have been conducted clarify its complex pathogenesis. This study was designed investigate whether BALB/c on a choline-deficient high-fat diet can be used as model for NASH. Materials Methods: male were fed L-amino acid-defined (CDAHFD) or...

10.21705/mcbs.v5i2.193 article EN cc-by-nc Molecular and Cellular Biomedical Sciences 2021-07-06

Abstract Background : We investigated the gut microbiota in patients with non-alcoholic fatty liver disease (NAFLD) and its correlation fibrosis steatosis as reflected controlled attenuation parameter transient elastography valuesMethods A cross-sectional study was performed on 37 NAFLD at Cipto Mangunkusumo National General Hospital from December 2018 to March 2019. The fecal samples 16S RNA sequencing using next-generation platform MiSeq (Illumina).Results more common metabolic syndrome....

10.21203/rs.3.rs-23643/v1 preprint EN cc-by Research Square (Research Square) 2020-04-22

Acutely decompensated liver cirrhosis is associated with high medical costs and negatively affects productivity quality of life. Data on factors in-hospital mortality due to acutely in Indonesia are scarce. This study aims identify predictors develop predictive scoring systems for clinical application patients.This was a retrospective cohort using hospital database data at Cipto Mangunkusumo National General Hospital, Jakarta (2016-2019). Bivariate multivariate logistic regression analyses...

10.1186/s12876-021-01972-6 article EN cc-by BMC Gastroenterology 2021-10-20

Hypoglycemia is one of the paraneoplastic syndrome manifestations that arise from primary and secondary liver cancer. usually presents in late stage disease indicates a poor prognosis. This case series displays characteristics profile patients with cancer who are presented hypoglycemia tertiary referral hospital Indonesia. The study included 41 were hypoglycemia. Hepatocellular carcinoma was diagnosed 51.2% patients, metastatic 14.6% undiagnosed 34.1% patients. mean age 47.7 years male...

10.1530/edm-23-0077 article EN cc-by-nc-nd Endocrinology Diabetes and Metabolism Case Reports 2024-07-01

Background: Esophageal varices occur at middle to advanced stages of cirrhosis and are associated with increased mortality due their potential for rupture bleeding. The aim this study is examine the accuracy a surrogate marker, Mac-2 binding protein glycosylation isomer (M2BPGi), screening high-risk esophageal in cirrhotic patients. Methods: Ninety-four patients who underwent endoscopy Cipto Mangunkusumo Hospital, Jakarta, Indonesia were included. Patients history ligation, portal vein...

10.3390/livers1020006 article EN cc-by Livers 2021-04-08

Pendahuluan. Hepatitis B kronis merupakan penyakit endemis di Indonesia yang umumnya diobati menggunakan interferon pegilasi dan analog nukleosida/nukleotida. Tujuan dari penelitian ini ialah untuk menilai efikasi terapi hepatitis pada pasien mendapatkan nukleosida/nukleotida (lamivudin, telbivudin, and tenofovir) selama periode tiga tahun. Metode. Penelitian meninjau catatan rekam medis secara retrospektif dengan infeksi mengunjungi Poliklinik Hepatobilier Rumah Sakit dr. Cipto Mangunkusumo...

10.7454/jpdi.v8i3.598 article ID cc-by-sa Jurnal Penyakit Dalam Indonesia 2021-10-02

Background: COVID-19 is a disease caused by infection of SARS-CoV-2 virus which leads to mortality due respiratory failure. The progression more severe in patients with pre-existence morbidities, including liver disease. Recently, few studie showed that cirrhosis had higher risk rather than without infection. Nevertheless, the study survival patient underlying still limited. aim this evaluate adult cirrhosisMethod: An observational Cipto Mangunkusumo Hospital was conducted. Patients between...

10.24871/2222021124-129 article EN cc-by The Indonesian Journal of Gastroenterology Hepatology and Digestive Endoscopy 2021-09-27

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10.24871/24120231 article cc-by The Indonesian Journal of Gastroenterology Hepatology and Digestive Endoscopy 2023-04-10

<h3>Background</h3> The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing. In Indonesia <b>Hasan, I et al. (2002)</b> reported the 30.6%. This study evaluated first time profile gut microbiota and correlation with severity NAFLD in Indonesia. <h3>Methods</h3> We included 37 subjects age 18–60 years. characteristic data patients food recalls were recorded. Abdominal ultrasound, transient elastography controlled attenuation parameter (CAP) performed. Next generation 16S rRNA...

10.1136/gutjnl-2019-iddfabstracts.5 article EN 2019-06-01

INTRODUCTION: Gastric varices (GV) presents in 10-30% of liver cirrhosis patients with mortality rate up to 45%. Isolated gastric rupture is less frequent than esophageal (EV) rupture, but the hemorrhage often more severe, difficult control, and have higher risk recurrent bleeding mortality. However, there are still debatable no clear consensus yet about optimal management especially for incidentally discovered IGV. METHODS: This was a cohort retrospective endoscopy database study at Dr....

10.14309/01.ajg.0000593972.33267.08 article EN The American Journal of Gastroenterology 2019-10-01

Introduction. Treatment of tuberculosis (TB) in HIV patients is complicated due to numerous comorbidities and possible adverse effects. One which cutaneous drug reaction (CADR). This event often difficult manage because multiple medications the get. The objective this study was know prevalence risk factors CADR among HIV-infected starting anti-TB treatment. Methods. retrospective reviewed data from medical records new at Working Group on AIDS outpatient clinic Cipto Mangunkusumo Hospital,...

10.7454/jpdi.v9i4.1020 article EN cc-by-sa Jurnal Penyakit Dalam Indonesia 2022-12-31
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