A5048353344- Clinical Nutrition and Gastroenterology
- Nutrition and Health in Aging
- Electrolyte and hormonal disorders
- Renal function and acid-base balance
- Diet and metabolism studies
- Intensive Care Unit Cognitive Disorders
- Abdominal Surgery and Complications
- Airway Management and Intubation Techniques
- Parathyroid Disorders and Treatments
- Magnesium in Health and Disease
- Hemodynamic Monitoring and Therapy
- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Biomedical and Chemical Research
- Tracheal and airway disorders
Karolinska University Hospital
2016-2024
Karolinska Institutet
2016-2024
Indirect calorimetry allows the determination of energy expenditure in critically ill patients by measuring oxygen consumption (VO2) and carbon dioxide production (VCO2). Recent studies have demonstrated variable performance "breath-by-breath" instruments compared to mixing chamber technology. The aim this study was validate two modern devices (E-sCOVX Quark RMR) against a reference method (Deltatrac II). Measurements VO2/VCO2 with test were performed simultaneously over 20-min period...
Providing supplemental amino acids to ICU patients during a 3-h period results in improved whole-body net protein balance, without an increase acid oxidation. The primary objective was investigate if 24-h intravenous infusion critically ill has sustained effect on balance as seen after 3 h. Secondary objectives were monitoring of oxidation rate, urea and free plasma concentrations.An [1-13C]-phenylalanine added ongoing enteral nutrition quantify the uptake acids. Primed infusions...
While gastrointestinal (GI) dysfunction is commonly encountered among critically ill patients, a uniform prospectively validated scoring system lacking. The present study aims to validate the recently developed Gastrointestinal Dysfunction Score (GIDS) in multicenter, prospective cohort of consecutive adult patients admitted intensive care units (ICU).
The high fashion in nutrition for the critically ill is to recommend a protein intake. Several opinion leaders are surfing on this wave, expanding suggested allowance upwards. At same time, there no new evidence supporting change recommendations. Observational data show that clinical practice intake most often far below current ESPEN recommendations of 1.2–1.5 g/kg/day. Therefore, it may be best interests our patients just adhere guideline, and not stretch them upwards intake? Here we give...
Background Enteral nutrition (EN) is a ubiquitous intervention in ICU patients but there uncertainty regarding the optimal dose, timing and importance for patient-centered outcomes during critical illness. Our research group has previously found an improved protein balance normocaloric versus hypocaloric parenteral neurosurgical patients. We now wanted to investigate if this could be demonstrated general population with established enteral feeding, including on renal replacement therapy....
BackgroundAberrations in blood phosphate (Pi) levels, whether presenting as hypo- or hyperphosphatemia, appear to be associated with clinical complications and adverse outcomes patients admitted an intensive care unit (ICU). However, the prevalence of Pi disorders association subsequent factors organ failures leading death ICU are poorly described. Despite endeavors understand etiology treatment low levels from systematic reviews meta-analyses, literature lacks comprehensive guidance for...