Merli Mändul

ORCID: 0000-0003-4444-5979
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About
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Research Areas
  • Abdominal vascular conditions and treatments
  • Abdominal Surgery and Complications
  • Gallbladder and Bile Duct Disorders
  • Esophageal and GI Pathology
  • Clinical Nutrition and Gastroenterology
  • Cardiac, Anesthesia and Surgical Outcomes
  • Aortic aneurysm repair treatments
  • Hemodynamic Monitoring and Therapy
  • Biliary and Gastrointestinal Fistulas
  • Genetic Associations and Epidemiology
  • Advanced Causal Inference Techniques
  • Ethics in medical practice
  • Enhanced Recovery After Surgery
  • Migraine and Headache Studies
  • Renal function and acid-base balance
  • Genetic and phenotypic traits in livestock
  • Pancreatitis Pathology and Treatment
  • Ethics and Legal Issues in Pediatric Healthcare
  • Neuroethics, Human Enhancement, Biomedical Innovations
  • Gastroesophageal reflux and treatments
  • Vascular anomalies and interventions
  • Neurological Complications and Syndromes
  • Neurological and metabolic disorders
  • Counseling Practices and Supervision
  • Intensive Care Unit Cognitive Disorders

University of Tartu
2021-2025

Czech Academy of Sciences, Institute of Mathematics
2023

Abstract Background The aim of this multicentre prospective observational study was to identify the incidence, patient characteristics, diagnostic pathway, management and outcome acute mesenteric ischaemia (AMI). Methods All adult patients with clinical suspicion AMI admitted or transferred 32 participating hospitals from 06.06.2022 05.04.2023 were included. Participants who subsequently shown not have had localized intestinal gangrene due strangulating bowel obstruction only baseline data...

10.1186/s13054-024-04807-4 article EN cc-by Critical Care 2024-01-23

SummaryBackground & aimsTo develop a five grade score (0–4 points) for the assessment of gastrointestinal (GI) dysfunction in adult critically ill patients.MethodsThis prospective multicenter observational study enrolled consecutive patients admitted to 11 intensive care units nine countries. At all sites, daily clinical data with emphasis on GI symptoms were collected and intra-abdominal pressure measured. In out biomarkers citrulline intestinal fatty acid-binding protein (I-FABP) measured...

10.1016/j.clnu.2021.07.015 article EN cc-by-nc-nd Clinical Nutrition 2021-07-18

Gastric residual volume (GRV) measurement to detect gastrointestinal (GI) dysfunction is a common diagnostic procedures in critical care, albeit still not well standardized being operator-, patient-, and tube-dependent. Our aim was describe current practice of GRV measurements its association with clinical outcomes critically ill patients.This secondary analysis an international prospective observational cohort study (intestinal-specific organ function assessment). Eligibility criteria were...

10.1002/jpen.2502 article EN cc-by-nc Journal of Parenteral and Enteral Nutrition 2023-03-28

Abstract Background Acute mesenteric ischaemia (AMI) is a life-threatening disease where early diagnosis critical to avoid morbidity and mortality from extensive irreversible bowel necrosis. Appropriate prediction of presence necrosis currently not available but would help choose the optimal method treatment. The study aims identify combinations biomarkers that can reliably AMI distinguish between potentially reversible ischaemia. Methods This prospective multicentre study. Adult patients...

10.1186/s12893-024-02491-3 article EN cc-by BMC Surgery 2024-07-03

While gastrointestinal (GI) dysfunction is commonly encountered among critically ill patients, a uniform prospectively validated scoring system lacking. The present study aims to validate the recently developed Gastrointestinal Dysfunction Score (GIDS) in multicenter, prospective cohort of consecutive adult patients admitted intensive care units (ICU).

10.1016/j.clnesp.2024.07.023 article EN cc-by Clinical Nutrition ESPEN 2024-07-27

Background: There are no clinical or laboratory markers that can diagnose acute mesenteric ischemia (AMI) accurately. This study aimed to find differences in and between arterial occlusive AMI other abdominal diseases where was initially suspected. Methods: a post hoc of an international prospective multicenter data on patients with suspected were collected. Independent factors associated evaluated multivariable logistic regression analysis. Results: The number 231, consisting thrombotic (n...

10.3390/diagnostics14232705 article EN cc-by Diagnostics 2024-11-30

Abstract Introduction Acute mesenteric ischaemia (AMI) is a life-threatening disease where early diagnosis critical to avoid morbidity and mortality from extensive irreversible bowel necrosis. Appropriate prediction of presence necrosis currently not available but would help choose the optimal method treatment. The study aims identify combinations biomarkers that can reliably AMI distinguish between potentially reversible ischaemia. Methods This prospective multicentre study. Adult patients...

10.21203/rs.3.rs-4087503/v1 preprint EN cc-by Research Square (Research Square) 2024-03-15

Taust ja eesmargid. Migreen on sagedasim sotsiaal-majanduslikult kulukaim neuroloogiline haigus, mis oluliselt halvendab elukvaliteeti. Uuringu eesmark oli saada ulevaade migreeni kasitlusest Eesti kahes suuremas kiirabiasutuses vorrelda neid ning kirjeldada kiirabi poolt migreenina kasitletud peavaluga patsiente nende ravi. Metoodika. Tegemist retrospektiivse kohortuuringuga, mille valimi moodustasid ajavahemikul 01.07.–31.12.2014 Tallinna Kiirabi Tartu visiitide need haigusjuhud, kus...

10.15157/ea.v0i0.13391 article ET Eesti Arst 2017-04-24
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