A5033847633- Mosquito-borne diseases and control
- Viral Infections and Outbreaks Research
- Seaweed-derived Bioactive Compounds
- Viral Infections and Vectors
- Plant Virus Research Studies
- Echinoderm biology and ecology
- Polysaccharides and Plant Cell Walls
- Carbohydrate Chemistry and Synthesis
- Marine and coastal plant biology
- Phytochemical compounds biological activities
- Viral gastroenteritis research and epidemiology
- Malaria Research and Control
- Herpesvirus Infections and Treatments
- Virus-based gene therapy research
- Poxvirus research and outbreaks
- Natural product bioactivities and synthesis
- Animal Virus Infections Studies
- Insect Pest Control Strategies
- Virology and Viral Diseases
- HIV Research and Treatment
- Biochemical and Molecular Research
- HIV/AIDS drug development and treatment
- Hepatitis B Virus Studies
- Viral Infections and Immunology Research
- Lipid Membrane Structure and Behavior
Consejo Nacional de Investigaciones Científicas y Técnicas
2016-2025
Fundación Ciencias Exactas y Naturales
2016-2025
University of Buenos Aires
2016-2025
Instituto de Química y Fisicoquímica Biológicas
1994-2023
Institute of Astronomy and Space Physics
2016-2022
Institute of Virology of the Slovak Academy of Sciences
2003
Università Cattolica del Sacro Cuore
2002
Entry of dengue virus 2 (DENV-2) into Aedes albopictus mosquito C6/36 cells was analysed using biochemical and molecular inhibitors, together with confocal electron microscopy observations. Treatment monodansylcadaverine, chlorpromazine, sucrose ammonium chloride inhibited DENV-2 yield protein expression, whereas nystatin, a blocker caveolae-mediated endocytosis, did not have any effect. Using microscopy, co-localization E glycoprotein the marker transferrin observed at periphery cytoplasm....
Natural compounds offer interesting pharmacological perspectives for antiviral drug development. In this study, we have analysed sulphated-fucan-containing fractions isolated from the brown seaweed Cystoseira indica. The crude water extract (CiWE) and main fraction (CiF3) obtained by anion exchange chromatography had potent activity against herpes simplex virus types 1 (HSV-1) 2 (HSV-2) without cytotoxicity Vero cell cultures. Furthermore, they no direct inactivating effect on virions in a...
The entry of two dengue virus (DENV) serotypes into Vero cells was analysed using biochemical inhibitors, dominant negative mutants cellular proteins involved in endocytic pathways, fluorescence microscopy and infectivity determinations. By treatment with dansylcadaverine chlorpromazine overexpression a form the Eps15 protein, clathrin-mediated endocytosis for productive DENV-1 internalization demonstrated whereas infectious DENV-2 same cell system independent clathrin. Treatment inhibitors...
Two new trisulfated triterpene glycosides, liouvillosides A (1) and B (2), have been isolated from the Antarctic sea cucumber Staurocucumis liouvillei. Their structures elucidated by spectroscopic analysis (NMR FABMS) chemical transformations. Liouvillosides (2) are two examples of a small number glycosides cucumbers belonging to family Cucumariidae. Both were found be virucidal against herpes simplex virus type 1 (HSV-1) at concentrations below 10 μg/mL.
Abstract Essential oils obtained from eight aromatic plants of San Luis Province, Argentina, were screened for virucidal activity against herpes simplex virus type 1 (HSV‐1), Junin (JUNV) and dengue 2 (DEN‐2). The most potent inhibition was observed with the essential oil Lippia junelliana turbinata JUNV concentration 50% (VC 50 ) values in range 14–20 ppm, whereas Aloysia gratissima , Heterotheca latifolia Tessaria absinthioides inhibited 52–90 ppm. time‐ temperature‐dependent. A. Artemisia...