A5063014179- Cerebrospinal fluid and hydrocephalus
- Dark Matter and Cosmic Phenomena
- Traumatic Brain Injury and Neurovascular Disturbances
- Atomic and Subatomic Physics Research
- Particle physics theoretical and experimental studies
- Fetal and Pediatric Neurological Disorders
- Neurosurgical Procedures and Complications
- Spinal Dysraphism and Malformations
- Particle Detector Development and Performance
- Chemical Thermodynamics and Molecular Structure
- Radiation Detection and Scintillator Technologies
- Cosmology and Gravitation Theories
- Thermodynamic properties of mixtures
- Phase Equilibria and Thermodynamics
- Chemical and Physical Properties in Aqueous Solutions
- Head and Neck Surgical Oncology
- Advanced MRI Techniques and Applications
- Analytical Chemistry and Chromatography
- Optical Imaging and Spectroscopy Techniques
- Intracerebral and Subarachnoid Hemorrhage Research
- Superconducting and THz Device Technology
- Neonatal and fetal brain pathology
- CCD and CMOS Imaging Sensors
- Advanced Semiconductor Detectors and Materials
- Neutrino Physics Research
Max Planck Institute for Physics
2008-2020
Saarland University
2006-2018
University of Coimbra
2017
Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali del Gran Sasso
2017
Excellence Cluster Universe
2017
Technical University of Munich
2017
Institute of High Energy Physics
2017
TU Wien
2017
University of Tübingen
2017
University of Oxford
2017
The CRESST-II cryogenic Dark Matter search, aiming at detection of WIMPs via elastic scattering off nuclei in CaWO4 crystals, completed 730 kg days data taking 2011. We present the collected with eight detector modules, each a two-channel readout; one for phonon signal and other coincidently produced scintillation light. former provides precise measure energy deposited by an interaction, ratio light to can be used discriminate different types interacting particles thus distinguish possible...
The CRESST-II experiment uses cryogenic detectors to search for nuclear recoil events induced by the elastic scattering of dark matter particles in CaWO$_4$ crystals. Given low energy threshold our combination with light target nuclei, mass can be probed high sensitivity. In this letter we present results from data a single detector module corresponding 52 kg live days. A blind analysis is carried out. With an recoils 307 eV substantially enhance sensitivity matter. Thereby, extend reach...
The CRESST-II cryogenic dark matter search aims for the detection of WIMPs via elastic scattering off nuclei in CaWO $$_4$$ crystals. We present results from a low-threshold analysis single upgraded detector module. This module efficiently vetoes low energy backgrounds induced by $$\alpha $$ -decays on inner surfaces detector. With an exposure 29.35 kg live days collected 2013 we set limit spin-independent WIMP-nucleon which probes new region parameter space WIMP masses below 3 GeV/c $$^2$$...
Models for light dark matter particles with masses below 1 GeV/c $$^2$$ are a natural and well-motivated alternative to so-far unobserved weakly interacting massive particles. Gram-scale cryogenic calorimeters provide the required detector performance detect these extend direct search program of CRESST. A prototype 0.5 g sapphire developed $$\nu $$ -cleus experiment has achieved an energy threshold $$E_{th}=(19.7\pm 0.9)$$ eV. This is one order magnitude lower than previous devices...
Abstract The CRESST experiment (Cryogenic Rare Even Search with Superconducting Thermometers), located at Laboratori Nazionali del Gran Sasso in Italy, searches for dark matter particles via their elastic scattering off nuclei a target material. consists of scintillating CaWO 4 crystals, which are operated as cryogenic calorimeters millikelvin temperatures. Each interaction the crystal produces phonon signal and light that is measured by second calorimeter. Since CRESST-II result 2015,...
Object The authors evaluated the safety and efficacy of antibiotic-impregnated shunt catheters (AISCs) determined cost–benefit ratio related to fact that AISCs increase implant costs a procedure by ~ $400 per patient. Methods control group comprised 98 adults with chronic hydrocephalus 22 children, who were treated without (non-AISCs). In treatment group, (Bactiseal, Codman, Johnson & Johnson) implanted in 171 26 children. minimum follow-up period was 6 months. Results Important risk...
Abstract BACKGROUND Ventriculoperitoneal shunt (VP-shunt) is the standard of treatment for idiopathic normal pressure hydrocephalus (iNPH). However, a thorough investigation VP-shunt complications in this population lacking. OBJECTIVE To present analysis and rates progressively occurring during first year after surgery patients with iNPH included European multicenter (EU-iNPH) study. METHODS Patients (n = 142) were prospectively EU-iNPH study by 13 institutions. All received programmable...
Abstract BACKGROUND: Little is known about variables associated with overdrainage complications and neurofunctional health-related quality of life outcomes in idiopathic normal-pressure hydrocephalus (iNPH) patients after shunt surgery. OBJECTIVE: To identify candidate demographic disease-specific predictors patient-related outcomes, allowing for more personalized care iNPH. METHODS: This was a secondary analysis the dataset SVASONA study, multicenter randomized trial comparing gravitational...
The experiment CRESST-II aims at the detection of dark matter with scintillating CaWO4 crystals operated as cryogenic detectors. Recent results on spin-independent WIMP-nucleon scattering from Phase 2 allowed to probe a new region parameter space for WIMP masses below 3 GeV/c2. This sensitivity was achieved after background levels were reduced significantly. We present extensive studies crystal, called TUM40, grown Technische Universität München. average beta/gamma rate 3.51/[kg keV day]...
The aim of this study was to investigate the relationship between pressure setting ventriculoperitoneal (VP) shunt valve and a magnetic resonance (MR)-based estimate intracranial (ICP) in children with shunt-treated hydrocephalus without clinical signs malfunction.Institutional review board approval obtained before study, all subjects and/or their legal guardians provided written informed consent. In prospective 15 consecutive patients (median age, 8.25 years; range, 2.2-18.4 6 girls 9 boys)...
The purpose of this document is to describe the upgrade CRESST dark matter search at LNGS. proposed strategy will allow explore a region parameter space for spin-independent WIMP-nucleon elastic scattering corresponding WIMP masses below 10GeV/c$^\text{2}$, that has not been covered by other experiments. These results can be achieved only with outstanding detector performances in terms threshold and background. This proposal shows how match these performance requirements, adding unique piece...
The cryogenic dark matter experiment CRESST-II aims at the direct detection of WIMPs via elastic scattering off nuclei in scintillating CaWO$_4$ crystals. We present a new, highly improved, detector design installed current run Phase 2 with an efficient active rejection surface-alpha backgrounds. Using sticks instead metal clamps to hold target crystal, housing fully-scintillating inner surface could be realized. presented (TUM40) provides excellent threshold ${\sim}\,0.60\,$keV and...
CRESST is a direct dark matter search experiment, aiming for an observation of nuclear recoils induced by the interaction particles with cryogenic scintillating calcium tungstate crystals. Instead confining ourselves to standard spin-independent and spin-dependent searches, we re-analyze data from CRESST-II using more general effective field theory (EFT) framework. On many EFT coupling constants, improved exclusion limits in low-mass region (< 3–4 GeV/ $$c^2$$ ) are presented.
The authors' goal in this paper was to evaluate prospectively the efficacy and safety of a new pediatric gravitational shunt determine whether it warrants inclusion randomized, controlled trial with other shunts.A total 55 children between ages 0 6 years (median age 0.5 years, average 4+/-6 years) underwent primary implantation; all received Miethke Paedi-GAV. follow-up period ranged 12 77 months (mean 47+/-21 months). end point study first failure necessitating revision. 1- 2-year survival...
Over the past decade, a gravity-assisted valve (GAV) has become standard device in many European pediatric hydrocephalus centers. Because comparative clinical outcome studies on design have not included any GAV, authors this trial evaluated early results of GAV applications population.For minimum 2 years monitored 169 182 hydrocephalic children who received at their first CSF shunt insertion (61.5%) or as substitute for differential pressure (38.5%) 1 7 Outcomes were categorized survival...
Mass and total-kinetic-energy (TKE) distributions of fission fragments from the spontaneous $^{262}[105]$ $^{256}\mathrm{Fm}$ have been obtained. No events with anomalously high TKE were observed, contrary to theoretical expectations. The mass distribution is very probably asymmetric similar obtained all spontaneously fissioning systems exception $^{257}\mathrm{Fm}$ $^{259}\mathrm{Fm}$.