M. Barale

ORCID: 0000-0003-3441-2014
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About
Contact & Profiles
Research Areas
  • Parathyroid Disorders and Treatments
  • Renal cell carcinoma treatment
  • Bone health and treatments
  • Bone health and osteoporosis research
  • Prostate Cancer Diagnosis and Treatment
  • Renal and Vascular Pathologies
  • Growth Hormone and Insulin-like Growth Factors
  • Pituitary Gland Disorders and Treatments
  • Vitamin D Research Studies
  • Urologic and reproductive health conditions
  • Pancreatic and Hepatic Oncology Research
  • Genetic Syndromes and Imprinting
  • Hormonal Regulation and Hypertension
  • Bladder and Urothelial Cancer Treatments
  • Prostate Cancer Treatment and Research
  • Colorectal Cancer Surgical Treatments
  • Bone and Joint Diseases
  • Ophthalmology and Eye Disorders
  • Renal and related cancers
  • Pharmacological Effects and Toxicity Studies
  • Sexuality, Behavior, and Technology
  • Metabolism, Diabetes, and Cancer
  • Organ Donation and Transplantation
  • Adrenal Hormones and Disorders
  • Sexual function and dysfunction studies

University of Turin
2013-2024

Fondazione Ricerca Molinette
2018-2022

Azienda Ospedaliera Citta' della Salute e della Scienza di Torino
2013

Yahoo (United Kingdom)
2002

Centre Hospitalier Universitaire de Besançon
1984

Abstract Background Vertebral fractures (VFs) are a frequent complication of acromegaly, but no studies have been so far published on effectiveness antiosteoporotic drugs in this clinical setting. Objective To evaluate whether real-life practice bone active may reduce the risk VFs patients with or controlled acromegaly. Study design Retrospective, longitudinal study including 9 tertiary care endocrine units. Patients and Methods Two hundred forty-eight acromegaly (104 males; mean age 56.00 ±...

10.1210/clinem/dgaa363 article EN The Journal of Clinical Endocrinology & Metabolism 2020-06-08

The glucagon stimulation test involves the peptide intramuscular or subcutaneous administration for diagnosis of hypopituitarism. To date, no data are available regarding its intranasal formulation. Our study intended to investigate role as a potential stimulus evaluation corticotropic, somatotropic, and antidiuretic axes.Non-randomized, single-blinded, cross-over including 10 healthy subjects (50% women).All participants underwent 2 days testing, placebo was administered. At baseline, every...

10.1093/ejendo/lvad019 article EN European Journal of Endocrinology 2023-02-09

Abstract Context Hyponatremia is associated with increased risk of osteoporosis and fractures. The impact hyponatremia on noninvasive indices bone quality, however, unknown. Objective To evaluate whether trabecular microarchitecture, assessed noninvasively by score (TBS), altered in patients hyponatremia. Methods We conducted a cross-sectional analysis the population-based 2005-2008 cycles National Health Nutrition Examination Survey, which TBS measurement was performed. main outcome...

10.1210/clinem/dgae234 article EN publisher-specific-oa The Journal of Clinical Endocrinology & Metabolism 2024-04-12

Abstract Background Osteoporosis is a common concern in the elderly that leads to fragile bones. Calcium supplementation plays crucial role improving bone health, reducing fracture risk, and supporting overall skeletal strength this vulnerable population. However, there conflicting evidence on safety of calcium supplements individuals. Aim The aim study was evaluate adherence, tolerability citrate osteopenic subjects. Methods In non-interventional, prospective, multicenter study, subjects...

10.1007/s40520-024-02696-9 article EN cc-by Aging Clinical and Experimental Research 2024-02-12

Abstract Context Chronic use of proton pump inhibitors (PPIs) has been associated with an increase in bone fragility. However, evidence on the effect chronic PPI density is conflicting, and data microarchitectural quality are scarce. Objective The primary aim this study was to evaluate whether trabecular microarchitecture, assessed by score (TBS), altered users. association between also evaluated as a secondary endpoint. Methods We extracted individual patient from 2005 2008 cycles...

10.1210/clinem/dgae598 article EN publisher-specific-oa The Journal of Clinical Endocrinology & Metabolism 2024-08-28

Abstract Background Fabry disease (FD) is an inherited X-linked lysosomal storage characterized by increased risk of osteoporosis and fractures. The impact FD on clinical measures bone quality unknown. This considered, aim our study was to evaluate whether trabecular microarchitecture, measured score (TBS), altered in patients with compared control subjects. Methods retrospective monocentric enrolled 14 (M/F 1/1, median age 46 [37–63] years, range 31–72 years) newly diagnosed between January...

10.1007/s40618-024-02427-x article EN cc-by Journal of Endocrinological Investigation 2024-10-03

Conventional glucocorticoids (C-GC) replacement regimens have a detrimental effect on skeletal health in patients with adrenal insufficiency (AI), ultimately leading to an increased fracture risk. The novel dual-release hydrocortisone (DR-HC) formulations are characterized by more favourable safety profile various clinical endpoints. Data comparing the impact of C-GC and DR-HC bone, however, scarce.Twenty-seven autoimmune primary AI (PAI; 13 treated 14 DR-HC) were evaluated compare...

10.3389/fendo.2023.1234237 article EN cc-by Frontiers in Endocrinology 2023-09-11

There are few data regarding the clinical outcome of patients with parathyroid carcinoma (PC) and atypical adenoma (AA) after surgery. Aim our study was to investigate disease recurrence mortality rate as well their predictors in a series PC or AA.Clinical biochemical parameters, histological features, incidence were retrospectively assessed 39 (51% males, mean age 56.2 ± 17.2 years) diagnosed (n=24) AA (n=15) followed up for 6.8 5.0 years surgery.No differences baseline characteristics...

10.3389/fendo.2023.1158474 article EN cc-by Frontiers in Endocrinology 2023-05-08

Abstract Despite the current debate on best therapeutic approach, i.e. symptomatic vs intensive strategy, one zoledronate (Zol) infusion is effective in most patients with Paget’s disease of bone (PDB), whereas few need retreatment, whose predictors are not well established. We aimed to evaluate long-term efficacy Zol therapy and retreatment PDB. Pagetic complications, clinical biochemical response together frequency were retrospectively assessed forty-seven PDB (age, mean ± SD: 72.5 8.9...

10.1007/s00223-021-00848-x article EN cc-by Calcified Tissue International 2021-04-19

10.1007/s40618-014-0173-7 article EN Journal of Endocrinological Investigation 2014-11-21

Abstract Purpose Cardiometabolic disorders are non-classical complications of hypercalcemic primary hyperparathyroidism (HC-PHPT), but whether this risk connotes normocalcemic PHPT (NC-PHPT) remains to be elucidated. We investigated cardiometabolic alterations in both forms PHPT, looking for their association with indices disease activity. Methods Patients HC-PHPT ( n = 17), NC-PHPT and controls 34) matched age, sex, BMI were assessed glucose, lipid, blood pressure alterations, history...

10.1007/s12020-024-04063-0 article EN cc-by Endocrine 2024-10-15
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