A5087544017- Sexual Differentiation and Disorders
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Diabetes and associated disorders
- Cardiovascular Disease and Adiposity
- Cardiovascular Function and Risk Factors
- Liver Disease Diagnosis and Treatment
- Diet and metabolism studies
- Adipose Tissue and Metabolism
- Parvovirus B19 Infection Studies
- Thyroid Cancer Diagnosis and Treatment
- Sperm and Testicular Function
- Diabetes Management and Research
- Urological Disorders and Treatments
- Pancreatic function and diabetes
- Urologic and reproductive health conditions
- Adrenal Hormones and Disorders
- Turkish Literature and Culture
- Diet, Metabolism, and Disease
- Skin Diseases and Diabetes
- Neurogenetic and Muscular Disorders Research
- Syphilis Diagnosis and Treatment
- Ultrasound Imaging and Elastography
- Dermatological and COVID-19 studies
- Autoimmune and Inflammatory Disorders
- Hormonal Regulation and Hypertension
Başkent University
2021-2025
Erzurum Regional Training and Research Hospital
2022
Istanbul Kent University
2022
Başkent University Hospital
2022
Sağlık Bilimleri Üniversitesi
2017-2020
Konya Food and Agriculture University
2017-2020
Konya Eğitim ve Araştırma Hastanesi
2015-2019
Necmettin Erbakan University
2012-2016
Selçuk University
2012
Dr Sami Ulus Çocuk Sağlığı ve Hastalıkları Eğitim ve Araştırma Hastanesi
2009
Nationwide Study of Turner Syndrome ABS TRACTObjective: syndrome (TS) is a chromosomal disorder caused by complete or partial X chromosome monosomy that manifests various clinical features depending on the karyotype and genetic background affected girls.This study aimed to systematically investigate key TS in relationship large pediatric Turkish patient population.Methods: Our retrospective included 842 karyotype-proven patients aged 0-18 years who were evaluated 35 different centers Turkey...
Abstract Objective: Children with congenital adrenal hyperplasia are considered to be at an elevated risk for cardiovascular morbidity and mortality. The objective of this study was evaluate the association between periaortic fat thickness cardiometabolic profile in children diagnosed hyperplasia. Method: A total 20 adolescents healthy control subjects were enrolled study. We investigated metabolic anthropometric parameters, comparing these values those group. Periaortic assessed using...
Abstract Purpose 17α Hydroxylase/17,20 lyase deficiency (17OHD) is a rare form of congenital adrenal hyperplasia, typically diagnosed in late adolescence with symptoms pubertal delay and hypertension. This study aimed to determine the clinical laboratory characteristics 17OHD cases gather data on disease management. Methods Data from 97 nationwide were analyzed using CEDD-NET web system. Diagnostic, follow-up findings, final heights patients evaluated. Results Mean age at admission was 13.54...
The aim of our study was to evaluate the associations between vitamin D deficiency, atherosclerosis and metabolic syndrome.Two hundred forty-seven obese children adolescents, 8-16 years age (body mass index>95 p) were included in study. Anthropometric measurements, blood pressure lipid profile, level carotid intima media thickness (c-IMT) measured. MS diagnosed according IDF criteria.The prevalance deficieny adolescent 46.6%. Low levels associated with increased carotis syndrome (p=0.03,...
ABS TRACTObjective: There is an increased risk of cardiovascular morbidity in children and adolescents with classical congenital adrenal hyperplasia (CAH), presumably associated obesity, hypertension, impaired glucose tolerance dyslipidemia.This study was designed to evaluate the metabolic profile a group CAH from perspective risk.Methods: Twenty-five patients 25 healthy controls were included study.Metabolic anthropometric parameters investigated compared these two groups.Results: Subjects...
Objective: Noonan syndrome (NS) is a multisystem disorder, and short stature its most striking manifestation.Optimal growth hormone (GH) treatment for NS still controversial.In this study, using nationwide registration system, we aimed to evaluate the characteristics clinical features of patients in Turkey their response GH treatment. Methods:Children adolescents with diagnosis were included inthe study.Laboratory assessment including standard stimulation test results evaluated.Height...
Peroxisome proliferator-activated receptors (PPARs) are nuclear proteins that regulate transcriptional responses to peroxisome proliferators. There has been limited research concerned with the childhood expression of these receptors. In this study, we aimed evaluate PPAR-gamma (PPAR-γ) concentrations and their relationship body mass index (BMI), ratio waist hip, blood pressure levels, insulin resistance lipid profile in obese children adolescents.Children aged 8-16 years old were included...
Abstract The study aimed to investigate the effectiveness of vascularization index (VI) obtained using superb microvascular imaging (SMI) technique in diagnosis Hashimoto thyroiditis (HT). thyroid glands 80 patients with HT and 107 healthy, asymptomatic participants were examined SMI. parenchyma echogenicity was evaluated, gland volume measured. Vascularization measurements performed by manually drawing contours free region interest color 2-dimensional SMI VI mode. quantitative values group...
What is already known on this topic? study adds?Hypophosphatemic rickets (HR) a rare renal phosphate wasting disorder commonly with X-linked inheritance.There no nationwide data HR initial and follow-up findings.The age of diagnosis was similar in good bad responders to conventional therapy.Good had better height standard deviation score admission.Higher treatment doses led nephrocalcinosis without any change serum levels phosphorus.Awareness the importance early complications should be improved.
Objective: In this study, our aim was to determine cardiovascular risk and cardiac function in prediabetic obese children adolescents. Methods:The study conducted on 198 adolescents 6-18 years of age.Anthropometric measurements, blood pressure oral glucose tolerance test, lipid profile, HbA1c levels patients were assessed.Prediabetes defined according American Diabetes Association criteria.Left ventricular mass index (LVMi), carotid intima-media thickness (c-IMT), tissue Doppler measurements...
Abstract Objective Accurate distinction between central pubertal precociousness (PP) and premature thelarche (PT) is important to guide treatment. Both greyscale ultrasonography (US) sonoelastography can be used examine breast tissue. The aim of this study investigate the performance US strain elastographic (SE) in diagnosis increased volume girls. Methods Sixty-three girls with development up 8 years age diagnosed PP PT were included prospective study. Basal luteinizing hormone (LH),...
Maturity onset diabetes of the young (MODY) occurs due to mutations in genes involved pancreatic beta cell function and insulin secretion, has heterogeneous clinical laboratory features, account for 1-5% all cases. The prevalence distribution MODY subtypes vary between countries. aim this study was evaluate characteristics, mutation distribution, phenotype-genotype relationship a large case series pediatric Turkish patients genetically diagnosed with MODY.
To evaluate the anthropometric features of girls with Turner syndrome (TS) at birth and presentation effect karyotype on these parameters. Data were collected from 842 patients TS 35 different centers, who followed-up between 1984 2014 whose diagnosis age ranged to 18 years. Of patients, 122 received growth hormone, estrogen or oxandrolone excluded, 720 included in study. In this cohort, frequency small for gestational (SGA) was 33%. The SGA 4.2% (2/48) preterm 36% (174/483) term neonates (P...
Abstract Background: The purpose of this study was to evaluate the macular choroidal thickness in obese children with and without insulin resistance (IR). Methods: Thirty-six patients obesity 26 healthy volunteers were included cross-sectional study. measured enhanced depth imaging optical coherence tomography (EDI-OCT) at fovea positions 500 μm, 1000 1500 μm nasal temporal fovea. measurements groups compared correlation between homeostasis model assessment (HOMA-IR) values evaluated....
Abstract In this study, parameters of metabolic syndrome and dehydroepiandrosterone sulfate (DHEAS) levels in obese children adolescents were evaluated the associations between these factors analyzed. One hundred 40 healthy children/adolescents included study. Pubertal stages, anthropometric blood pressure measurements recorded. Levels fasting serum lipids, glucose, insulin, DHEAS, liver function tests determined. Carotid intima-media thickness (CIMT) was measured using two-dimensional...