A5076439272- Antibiotic Resistance in Bacteria
- Antiplatelet Therapy and Cardiovascular Diseases
- Helicobacter pylori-related gastroenterology studies
- Nosocomial Infections in ICU
- Antibiotic Use and Resistance
- Bacterial Identification and Susceptibility Testing
- Veterinary medicine and infectious diseases
- Autophagy in Disease and Therapy
- Bacterial biofilms and quorum sensing
- Flavonoids in Medical Research
- Vibrio bacteria research studies
- Hemophilia Treatment and Research
- Cardiac, Anesthesia and Surgical Outcomes
- Antimicrobial Resistance in Staphylococcus
- Mycobacterium research and diagnosis
- Facial Rejuvenation and Surgery Techniques
- Antibiotics Pharmacokinetics and Efficacy
- Genomics, phytochemicals, and oxidative stress
- Infections and bacterial resistance
- Breast Implant and Reconstruction
- Neurological Disease Mechanisms and Treatments
- Mitochondrial Function and Pathology
- Immune cells in cancer
- Body Image and Dysmorphia Studies
- Neuroinflammation and Neurodegeneration Mechanisms
Chinese PLA General Hospital
2009-2025
University of Cambridge
2022
Fuyang City People's Hospital
2021
Hangzhou Medical College
2019
Zhejiang Provincial People's Hospital
2019
University of Cincinnati Medical Center
2018
Hofstra University
2018
Phelps Hospital
2018
Northwell Health
2018
Ankang City Central Hospital
2017
ABSTRACT The biofilm structure of Helicobacter pylori is known to enhance its capabilities for antimicrobial resistance. This study aims investigate the role flagellar hook length control protein gene fliK in formation H. . Homologous recombination was employed knock out NCTC 11637 strain. flagella were observed using transmission electron microscopy (TEM), whereas motility and growth examined through semi-solid agar assays curve analyses, respectively. bacterial constituents visualized...
Tuberculosis (TB), predominantly caused by Mycobacterium tuberculosis (MTB) infection, remains a prominent global health challenge. Macrophages are the frontline defense against MTB, relying on autophagy for intracellular bacterial clearance. However, MTB can combat and evade autophagy, it influences macrophage polarization, facilitating immune evasion promoting infection. We previously found that heparin-binding hemagglutinin (HBHA) inhibits in A549 cells; however, its role polarization unclear.
Acinetobacter baumannii has been reported increasingly as a significant causative organism of various nosocomial infections, including hospital-acquired pneumonia (HAP). The aim this study was to investigate the clinical characteristics HAP induced by carbapenem-resistant A. (CRAB) in elderly patients and vitro antimicrobial effects cefoperazone/sulbactam combination therapy.Seventy-one geriatric ward General Hospital People's Liberation Army (PLAGH) with CRAB-induced were analyzed...
Breast augmentation is the most common cosmetic surgery in United States. Squamous cell carcinoma (SCC) of breast raises suspicion possibly metastatic origin. Here, we report an unusual case implant-associated SCC post silicone gel implant. The patient a 46-year-old female with breast. She initially had implantation for 1995. multiple revisions due to swelling and hardening. In 2016, she underwent bilateral prosthesis explantation capsulectomy. pathology demonstrated 4-cm tumor that was...
Clostridium difficile infection (CDI) is an emerging healthcare problem in the world. The purpose of this study was to perform a systematic epidemiological research CDI Tongji hospital, central China. Stool samples from hospitalized adults suspected were enrolled. diagnosis based on combination clinical symptoms and laboratory results. Clinical features non-CDI patients compared by appropriate statistical tests determine risk factors CDI. Multilocus sequence typing (MLST) employed for...
Mulberry granules (MLD) is a traditional Chinese medicine prescription that has been used in the treatment of diabetes for many years. Recently, we found MLD protected heart from diabetes-associated cardiomyopathy when it was to treat diabetes. However, beneficial effects and possible mechanism remain unknown. To elucidate these effects, an experimental myocardial ischemia/reperfusion (MI/R) injury model rats this study. Male C57BL/6 mice were injected with streptozotocin induce The...
Background: The concept of developmental hemostasis has been universally accepted. Physiological reference ranges for coagulation tests are available infants and children different ages. However, on Oriental they rare.
The benefits of intraarterial thrombolytic treatment (IATT) in reversing hyaluronic acid (HA)-related visual deficits remain unclear. This study aimed to report a 5-year experience the resulting from HA embolization by IATT tertiary medical center.
This study conducted an phenotypic and whole-genome sequencing analysis with
Rapid increase in resistance of Helicobacter pylori (H. pylori) has hindered antibiotics-based eradication efforts worldwide and raises the need for additional approaches. Here, we investigate role zinc-based compounds inhibiting H. growth modulating antibiotic sensitivities, interrogate their downstream transcriptomic changes, highlight potential mechanism driving observed effects. We showed that zinc acetate inhibited increased sensitivity to levofloxacin. Transcriptomic profiling distinct...
Myocardial infarction (MI) has likely contributed to the increased prevalence of heart failure (HF). As a result reduced cardiac function, splanchnic blood flow decreases, causing ischemia in villi and damage intestinal barrier. The induction heme oxygenase-1 (HO-1) could prevent, or lessen effects stress inflammation. Thus, effect mechanism thereof HO-1 on intestines rats with HF was investigated.Male Wistar through ligation left coronary artery were identified an ventricular ejection...
Exposure to a catastrophic event or intense stimulation can trigger fear memories, and the threatening memories persist even over lifetime. therapy is based on extinction learning widely used treat fear-related disorders, but its effect remote memory modest. Berberine, an isoquinoline alkaloid derived from
Objective To detect the effect of extracellular Ca2+ concentrations on test results coagulation-related parameters.Methods Blood samples outpatient medical volunteers were collected and then different doses calcium chloride added.The rate platelet aggregation (n=42),prothrombin time (PT),thrombin (TT) activated partial thromboplastin (APTT) (n=21) parameters thromboelastography (n=30) detected according to standard protocols by plasma turbidimetry,coagulation recalcification...
Background . The prevalence of a variety carbapenemases in Gram-negative bacteria (GNB) has posed global threat on clinical control and management. Monitoring controlling the carbapenemase-producing GNB became imperative tasks for many healthcare centers. aim this study was to develop high-throughput, specific, sensitive, rapid DNA microarray-based method diagnosis, phenotypic confirmation, molecular epidemiological carbapenemase genes. Methods We targeted panel eight genes, including...
Background The escalating resistance of Klebsiella pneumoniae , a prevalent pathogen in healthcare settings, especially its carbapenem-resistant K. (CRKP), to wide array antibiotics, notably β-lactams, constitutes formidable challenge for and global public health management. Methods This research compared the phenotypes genomic profiles CRKP Non-CRKP isolates Beijing hospital, focusing on high-risk bla KPC-2 gene-bearing clones structure mobile genetic elements facilitating their spread...
Retinal degeneration (RD) is a common eye disease which may result in blindness. At present, there no effective clinical treatment for RD. It known that apoptosis causes the occurrence and development of retinal degeneration, therefore antiapoptotic/antioxidative has always been focus There are many kinds antioxidant drugs, among natural antioxidants featured with reliable sources, high safety less side effects. Hence researchers across world made tremendous efforts finding safe...
Abstract Background : Rapid increase in resistance of Helicobacter pylori (H. pylori) has hindered antibiotics-based eradication efforts worldwide and raises the need for additional approaches. Here, we investigate role zinc-based compounds inhibiting H. growth modulating antibiotic sensitivities, interrogate their downstream transcriptomic changes highlight potential mechanism driving observed effects. Results We showed that zinc acetate inhibited increased sensitivity to levofloxacin....