A5015260067- 3D Printing in Biomedical Research
- Hippo pathway signaling and YAP/TAZ
- Advanced Sensor and Energy Harvesting Materials
- Electrospun Nanofibers in Biomedical Applications
- Urinary Tract Infections Management
- High-pressure geophysics and materials
- Neuroscience and Neural Engineering
- IoT-based Smart Home Systems
- Thermal properties of materials
- Additive Manufacturing and 3D Printing Technologies
- Cellular Mechanics and Interactions
- Reproductive tract infections research
- Microfluidic and Bio-sensing Technologies
- Neurogenesis and neuroplasticity mechanisms
- earthquake and tectonic studies
- Non-Invasive Vital Sign Monitoring
- PI3K/AKT/mTOR signaling in cancer
- Silk-based biomaterials and applications
- Ubiquitin and proteasome pathways
- Protein Tyrosine Phosphatases
- Pancreatic function and diabetes
- Wnt/β-catenin signaling in development and cancer
- Glioma Diagnosis and Treatment
- Tissue Engineering and Regenerative Medicine
- Gut microbiota and health
Shiraz University
2023
University of Victoria
2020-2022
Sharif University of Technology
2021
Icahn School of Medicine at Mount Sinai
2010-2016
The Graduate Center, CUNY
2016
Abstract Burn injuries represent a major life‐threatening event that impacts the quality of life patients, and places enormous demands on global healthcare systems. This study introduces fabrication characterization novel wound dressing made core–shell hyaluronic acid–silk fibroin/zinc oxide (ZO) nanofibers for treatment burn injuries. The configuration enables loading ZO—an antibacterial agent—in core nanofibers, which in return improves sustained release drug maintains its bioactivity....
Abstract An effective treatment of human diseases using regenerative medicine and cell therapy approaches requires a large number cells. Cultivation cells on microcarriers is promising approach due to the high surface‐to‐volume ratios that these offer. Here, multifunctional temperature‐responsive (cytoGel) made an interpenetrating hydrogel network composed poly( N ‐isopropylacrylamide) (PNIPAM), poly(ethylene glycol) diacrylate (PEGDA), gelatin methacryloyl (GelMA) are developed. A...
Wound infection is a major clinical challenge that can significantly delay the healing process, create pain, and requires prolonged hospital stays. Pre-clinical research to evaluate new drugs normally involves animals. However, ethical concerns, cost, challenges associated with interspecies variation remain obstacles. Tissue engineering enables development of in vitro human skin models for drug testing. existing engineered are representative healthy its normal functions. This paper presents...
Abstract In primary brain tumors, oncogenes are frequently amplified and maintained on extrachromosomal DNA as double minutes (DM), but the underlying mechanisms remain poorly understood. We have generated a mouse model of malignant glioma based knock-in mutant PDGF receptor α (PDGFRα) that is expressed in oligodendrocyte precursor cells (OPCs) after activation by Cre recombinase. tumor suppressor INK4/Arf −/− background, animals developed tumors resembling anaplastic human gliomas (WHO...
Hippo signaling acts as a master regulatory pathway controlling growth, proliferation, and apoptosis also ensures that variations in proliferation do not alter organ size. How the coordinates restricting with size control remains major unanswered question. Here we identify Rae1 highly-conserved target of Pathway integrating Genetic biochemical studies Drosophila cells tissues mammalian indicate promotes degradation downstream Warts/Lats. In proliferating cells, loss restricts cyclin B levels...
Alcohol-mediated cancers represent more than 3.5% of cancer-related deaths, yet how alcohol promotes cancer is a major open question. Using Drosophila, we identified novel interactions between dietary ethanol and loss tumor suppressor components the Hippo Pathway. The Pathway suppresses tumors in flies mammals by inactivating transcriptional co-activator Yorkie, spectrum associated with impaired signaling overlaps strikingly those alcohol. Therefore, our findings may implicate suppression...
Investigation of parent magma evolution and origin chromites in Cheshmeh-Bid, ophiolite Neyriz, Fars
Electrospun nanofiber is one of the promising alternatives for use in tissue engineering and drug delivery due to its controllable characteristics. However, choosing an appropriate biomaterial a specific regeneration plays significant role fabricating functional tissue-engineered constructs. Heart extracellular matrix (ECM)-derived electrospun which mimic physicochemical structural characteristics cardiac advantageous engineering. In this study, acellular calf heart ECM has been investigated...
Textile humidity and temperature sensors have a wide range of applications in clothing, management wounds, monitoring patient health. Despite recent advances the field, effect coupling on textile has been ignored. Here, we present multi-step roll to dip-coating method produce meters nano-particle infused cotton threads with fluorinated ethylene propylene (FEP) coating. The FEP coating deconvolutes dependency readings humidity. A hybrid sensor was then constructed by integrating FEP-coated...
Multifunctional Microcarriers In article number 2103192, Mohsen Akbari and co-workers engineer multifunctional microcarriers for high-throughput cell culture. These support growth, can locally deliver biomolecules such as growth factors to the attached cells, allow subsequent harvesting via altered environmental temperature. hold great promise an industrial-scale culture of therapeutic cells cell-based therapies regenerative medicines.