A5011360086- Plant Water Relations and Carbon Dynamics
- Meteorological Phenomena and Simulations
- Barrier Structure and Function Studies
- Climate variability and models
- Atmospheric and Environmental Gas Dynamics
- Plant responses to elevated CO2
- Tree-ring climate responses
- Acute Myeloid Leukemia Research
- Advanced Glycation End Products research
- T-cell and Retrovirus Studies
- Skin and Cellular Biology Research
- Intraocular Surgery and Lenses
- Chronic Myeloid Leukemia Treatments
- Nuclear Structure and Function
- CAR-T cell therapy research
- Microtubule and mitosis dynamics
- Immune Cell Function and Interaction
- Hepatitis Viruses Studies and Epidemiology
- Veterinary medicine and infectious diseases
- Cancer Cells and Metastasis
- Glaucoma and retinal disorders
- Ocular Infections and Treatments
- Circular RNAs in diseases
- Retinal Diseases and Treatments
- Climate change and permafrost
Hokkaido University
2023
Inouye Eye Hospital
2020-2022
Asahikawa University
2021
Kobe Pharmaceutical University
2021
Sapporo Science Center
2020-2021
Gifu University
2014-2021
Sapporo Kosei General Hospital
2020
Asahikawa Medical University
2020
Kyoto University
1996-2019
Suzuka University of Medical Science
2019
Abstract The water and energy exchanges in forests form one of the most important hydro‐meteorological systems. There have been far fewer investigations heat exchange high latitude than those warm, humid regions. few observations this system Siberia for an entire growing season, including snowmelt leaf‐fall seasons. In study, characteristics budgets eastern Siberian larch forest were investigated from season to season. latent flux was strongly affected by transpiration activity trees...
The cellular origin, in vivo function and fate of donor bone marrow-derived cells residing the recipient intestinal epithelial cells, pericryptal myofibroblasts or endothelial remain obscure. Although 'immunoprivileged' mesenchymal stem (MSCs) are prime candidates for cell- gene-based therapy, their precise role colitis remains largely undetermined. Using a dextran sulphate sodium (DSS) with busulphan (BU)-induced hypoplastic marrow model, we examined therapeutic effects MSC transplantation,...
Aim To characterize hepatitis E in M ie prefecture and to investigate whether raw pig liver sold as food is contaminated with virus ( HEV ) strains similar those recovered from patients. Methods Seventeen patients sporadic acute treated 2004 2012 were studied. A total of 243 packages regional grocery stores tested for the presence RNA . The partial genomic sequences human swine isolates determined subjected phylogenetic analyses. Results 17 segregated into genotype 3 n = 15) 4 2), 15 further...
Abstract To examine the possibility of heterogeneous mechanisms in proliferation adult T cell leukemia (ATL) cells, leukemic cells from 13 patients, nine acute-type and four chronic-type ATL, were examined for production interleukin 2 (IL 2) with or without mitogenic stimulation their response to recombinant IL when exogeneously added. The classified into groups, as follows. Group 1 (two patients): Cells this group produced messenger RNA, secreted 2, proliferated cultured mitogen-free...
Mogamulizumab (Mog), a humanized anti-CC chemokine receptor 4 (CCR4) mAb that mediates antibody-dependent cellular cytotoxicity (ADCC) using FcγR IIIa (CD16)-expressing effector cells, has recently been approved for treatment of CCR4-positive adult T-cell leukemia (ATL) in Japan. However, Mog failure sometimes observed patients who have accompanying chemotherapy-associated lymphocytopenia. In this study, we examined whether adoptive transfer artificial ADCC cells combined with would overcome...
Sensible and latent heat fluxes are important parameters for understanding energy/mass interactions. At present, there a number of methods available to estimate these fluxes, with varying degrees difficulty success. In the present study, we explore use flux variance method surface renewal sensible in two agricultural sites China. The results were compared direct measurements using eddy covariance. study sites, wheat field semi-arid area rice paddy humid provide an opportunity examine extreme...
High mobility group box 1 protein (HMGB1) is involved in the pathogenesis of inflammatory bowel disease (IBD). Patients with IBD develop zinc deficiency. However, detailed roles HMGB1 and deficiency intestinal epithelial barrier cellular metabolism remain unknown. In present study, Caco-2 cells 2D culture 2.5D Matrigel were pretreated transforming growth factor-β (TGF-β) type receptor kinase inhibitor EW-7197, epidermal factor (EGFR) AG-1478 a TNFα antibody before treatment cytokines (TNFα...
High mobility group box 1 (HMGB1) is involved in the induction of airway inflammation and injury patients with chronic obstructive pulmonary disease (COPD) idiopathic fibrosis (IPF). HMGB1 increased by transforming growth factor-β1 (TGF-β1), impairs epithelial barrier function lung. In present study, to investigate how affects normal human lung (HLE) cells, monolayer cells (2D culture) bronchial-like spheroid (2.5 D Matrigel culture), which have lumen formation, were pretreated TGF-β type I...
Abstract Observations of the surface layer and atmospheric boundary (ABL) were collected as part Lower Atmosphere Precipitation Study (LAPS), which investigated relationship between conditions ABL processes. The LAPS was Core Research for Evolutional Science Technology (CREST) program, under auspices Japan Agency (JST). began in August 2003 over a flat region mid‐latitude China at 32·55°N, 116·78°E. before, during, after Meiyu season provided data varying from relatively dry to moist....
Desmin is a type III intermediate filament (IF) component protein expressed specifically in muscular cells. phosphorylated by Aurora-B and Rho-kinase at the cleavage furrow from anaphase to telophase. The disturbance of this phosphorylation results formation unusual long bridge-like IF structures (IF-bridge) between two post-mitotic (daughter) Here, we report that desmin also serves as an excellent substrate for other mitotic kinase, Cdk1. Cdk1 loses its ability form IFs vitro. We have...
森林における降雨中および降雨後の蒸発散過程を明らかにするために, 滋賀県南部に位置する桐生水文試験地内のヒノキ林において降雨量, 蒸発量, 蒸散量, 葉の濡れ具合を観測した. 電気抵抗を利用した濡れセンサーおよびヒートパルス法によって, 降雨によって樹冠は上方から濡れていき, 降雨終了後, 上方の樹冠が乾いていくにしたがって蒸散活動が活発になる様子が観測された. 渦相関·熱収支法によって下向き (大気から樹冠へ) の顕熱フラックスが観測され, 遮断蒸発量は日中のピーク時で約250Wm-2に達した. 多層モデルを用いて, 蒸発·蒸散量および樹冠濡れ具合の再現計算を行った. 遮断蒸発に関わるパラメータの決定に際して濡れセンサーで観測された樹冠濡れ時間および渦相関法によって測定された顕熱フラックスを用いた. 潜熱フラックスの経時変化は良好に再現できたが, 樹冠濡れ具合に関して樹冠上層での適合性が悪かった. 解析期間中の再現計算された遮断蒸発量は水収支法によって求められた値より過小になった. 再現計算された蒸発散量は渦相関·熱収支法によって求められた蒸発散量と同程度となった.
Abstract Horizontal wind speed and vertical fluctuation data obtained from aircraft during the GEWEX Asian Monsoon Experiment‐Siberia (GAME‐Siberia) project revealed development of a local circulation in atmospheric boundary layer (ABL) near Lena River, Siberia. distributions showed regions where direction was opposite that synoptically dominant flow. horizontally averaged fluctuations with 4‐km cut‐off distance were used to derive air stream vectors. The vectors circulations only over...
Mice deficient for Spa-1 encoding Rap GTPase-activating protein develop myeloproliferative disorder (MPD) of late onset with frequent blast crises. The mechanisms MPD development as well the reasons long latency, however, remain elusive. We demonstrate here that preleukemic, disease-free Spa-1(-/-) mice show reduced steady-state hematopoiesis and attenuated resistance to whole body γ-ray irradiation, which are attributable sustained p53 response in hematopoietic progenitor cells (HPCs)....
Abstract The purpose of this study is to clarify the characteristics convective boundary layer (CBL) over a humid terrestrial area, Huaihe River basin in China, which covered by large, nearly flat plain with uniform farmland. Data were collected early summer 2004 using 32-m flux tower and 1290-MHz wind profiler radar. When mature wheat fields or bare dominated (the first period), sensible heat (SHF) from land surface was equal latent (LHF). After vegetation changed paddy second LHF much...