A5049129485- Platelet Disorders and Treatments
- Blood groups and transfusion
- Diabetes Treatment and Management
- Cytomegalovirus and herpesvirus research
- Hemophilia Treatment and Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Complement system in diseases
- Immunodeficiency and Autoimmune Disorders
- Monoclonal and Polyclonal Antibodies Research
- Multiple Myeloma Research and Treatments
- HIV Research and Treatment
- CAR-T cell therapy research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Pharmaceutical studies and practices
- Erythropoietin and Anemia Treatment
- Chronic Myeloid Leukemia Treatments
- Protein Degradation and Inhibitors
- Health Systems, Economic Evaluations, Quality of Life
- Immune Cell Function and Interaction
- Pharmaceutical Economics and Policy
Semmelweis University
2018-2022
Unified Szent István and Szent László Hospital
2013-2018
Viral reactivation is a frequent complication of allogeneic hematopoietic stem cell transplantation especially in children. For refractory cases, rapid virus-specific T-cell therapy would be ideally implemented within few days. Over the course year our pediatric cohort 43 transplantation, 9 patients fulfilled criteria for therapy. infections were due to cytomegalovirus (CMV) 3, Epstein-Barr virus (EBV) 2, and adenovirus (AdV) 1 case, whereas >1 was detected 3 cases. diseases necessitating...
Acquired hemophilia A (AHA) is a rare severe autoimmune bleeding disorder with significant morbidity and mortality. Although critical for disease control, there no consensus the best immunosuppressive regimen. Most authors use steroids first line, followed by other agents steroid failures. Upfront combined regimens offer advantage of reduced exposure toxicity as well increased efficacy. We retrospectively analyzed data from 32 patients AHA treated on an identical such institutional protocol:...
Objective: Response to treatment in multiple myeloma (MM) is routinely measured by serum and urine M-protein free light chain (FLC), as described the International Myeloma Working Group (IMWG) consensus statement. A non-negligible subgroup of patients however present without measurable biomarkers, others become oligo or non-secretory during recurrent relapses. The aim our research was evaluate soluble B-cell maturation antigen (sBCMA) a monitoring marker concurrent with standard MM at...
Abstract Distant metastasis is a major cause of colorectal cancer–related death, but the mechanism tumour progression not fully understood. There growing evidence an interaction between cells and platelets which may influence formation. Quality quantity von Willebrand factor regulate platelets. Our aim was to measure platelet count, antigen (VWF:Ag) levels ADAMTS13 activity in large (n = 232) cohort cancer patients examine their relationships with stage disease 5-year survival without...
Background A number of new assays with different measuring principles are available to measure von Willebrand factor (VWF) glycoprotein Ib (GPIb)-binding activity, but little is known about how these might behave differently for subtypes disease (VWD). Objectives The Comparison Assays Measure VWF Activity (COMPASS-VWF) study was designed compare all GPIb-binding activity VWF. We specifically searched particular assay behavior differences. Patients/Methods To sort out random differences from...
Background and objectives Administration of virus‐specific T cells (VSTs) is a viable antiviral treatment strategy after allogeneic HSCT, even if conventional therapies fail. Third‐party donors are often chosen for the generation VST product. The eligibility donor has to be tested in rigorous screening procedure, since isolation technology only targets pre‐existing VSTs. Materials methods In period 3 years, we performed 32 treatments 28 patients. Targeting four different viruses, 284 healthy...