A5052064375- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Synthesis and biological activity
- Synthesis and Biological Evaluation
- Synthesis and Reactions of Organic Compounds
- Reproductive tract infections research
- Synthesis and Characterization of Heterocyclic Compounds
- Fluorine in Organic Chemistry
- Click Chemistry and Applications
- Synthesis of Organic Compounds
- Bone Tissue Engineering Materials
- Syphilis Diagnosis and Treatment
- HIV, TB, and STIs Epidemiology
- Diatoms and Algae Research
- Polymer Surface Interaction Studies
- Cervical Cancer and HPV Research
- Urinary Tract Infections Management
- Bacterial Identification and Susceptibility Testing
- Synthesis of Tetrazole Derivatives
- Synthesis of heterocyclic compounds
- Electrospun Nanofibers in Biomedical Applications
- Reproductive System and Pregnancy
- Urological Disorders and Treatments
- Phenothiazines and Benzothiazines Synthesis and Activities
- Quinazolinone synthesis and applications
Ural Scientific Research Institute of Dermatovenerology and Immunopathology
2014-2024
Ekaterinburg State Theatre Institute
2019
Ministry of Health of the Russian Federation
2015-2019
Institute of Dermatology
2018
Abstract The present work reports on the synthesis of series azolo[5,1‐ c ][1,2,4]triazines and derivatives azoloazapurines. synthesized compounds were tested in vitro for antibacterial activity against N. gonorrhoeae antimycotic Trichophyton interdigitale , Epidermophyton floccosum, Microsporum canis Candida albicans . It was found that 10 3‐nitroazolo[5,1‐ ][1,2,4]triazine‐4‐amines 4 exhibit high (MIC≤15 μg/ml), but do not activity. For active a biological target predicted from...
A new route to aminocyclohexenones is reported.
A series of 6-fluoroaryl substituted [1,2,4]triazolo [1,5-a]pyrimidines have been synthesized by using the microwave-assisted Suzuki cross-coupling reaction from readily available 6-bromo-[1,2,4]triazolo[1,5-a]pyrimidine.The antimicrobial activity new compounds has evaluated in vitro against Mycobacterium tuberculosis H37Rv and gram-negative (Neisseria gonorrhoeae ATCC 49226) bacteria.
Aim. Of the study is to assess cervical mucus neutrophils functional status depend on dominant lactobacillus strain in I trimester of pregnancy women. Material and methods. We definded 40 strains obtained from genital tract pregnant used mass spectrometry analysis identify vaginal lactobacilli evaluated biofilm formation. Also, we studied viability, lysosomal activity, spontaneous induced NBT test (Nitroblue Tetrazolium test), ability absorb latex particles. Isolated were divided into 3...
A series of novel [1,2,4]triazolo[1,5-b][1,2,4,5]tetrazines has been synthesized through oxidation reaction the corresponding 3,6-disubstituted 1,2,4,5-tetrazines bearing amidine fragments. It is shown that heterocyclic systems obtained can be modified easily at C(3) position in reactions with aliphatic alcohols and amines. Also, reactivity towards CH-active compounds studied. The triazolo[1,5-b]annulated proved to active micromolar concentrations vitro against filamentous anthropophilic...