A5100420724- Mass Spectrometry Techniques and Applications
- Analytical Chemistry and Chromatography
- Analytical chemistry methods development
- Metabolomics and Mass Spectrometry Studies
- History and advancements in chemistry
- Advanced Proteomics Techniques and Applications
- Ion-surface interactions and analysis
- Various Chemistry Research Topics
- Photonic and Optical Devices
- GaN-based semiconductor devices and materials
- Isotope Analysis in Ecology
- Random lasers and scattering media
- Ga2O3 and related materials
- Advanced Chemical Sensor Technologies
- Nuclear Physics and Applications
- Pesticide Residue Analysis and Safety
- Semiconductor Quantum Structures and Devices
- Spectroscopy and Laser Applications
- Optical Coatings and Gratings
- Bacterial Identification and Susceptibility Testing
- Optical Polarization and Ellipsometry
- Advanced Antenna and Metasurface Technologies
- Semiconductor Lasers and Optical Devices
- Superconducting and THz Device Technology
- CCD and CMOS Imaging Sensors
Beijing Technology and Business University
2025
Shandong Institute of Metrology
2024
Central South University
2024
Tsinghua University
2023
Xidian University
2013-2021
National University of Singapore
2015-2020
Shanghai Institute of Technical Physics
2016-2018
Chinese Academy of Sciences
2014-2018
East China Normal University
2016-2017
University of Alberta
1991-2016
Matrix-assisted laser desorption/ionization (MALDI) time-of-flight mass spectrometry (TOFMS) can be used for rapid detection of bacteria proteins in a crude mixture. It potentially as tool bacterial identification based on the spectral patterns or appearance some characteristic peaks. However, there are many experimental parameters that have strong effect observed spectra. The objective this work is to address reproducibility issue. Several may affect MALDI spectra systematically...
Excessive host inflammatory responses negatively impact disease outcomes in respiratory infection. Host-pathogen interactions during the infective phase of influenza are well studied, but little is known about host's response repair stage. Here, we show that infection stimulated expression angiopoietin-like 4 (ANGPTL4) via a direct IL6-STAT3-mediated mechanism. ANGPTL4 enhanced pulmonary tissue leakiness and exacerbated inflammation-induced lung damage. Treatment infected mice with...
A technique using pulsed laser desorption is described as a means of volatilizing nonvolatile and thermally labile molecules into the gas phase for entrainment in supersonic jet expansions. By carefully controlling power by glycerol matrix to provide thin even film sample, repetitive can be achieved over an extended period performing spectroscopy. Using resonant two-photon ionization spectroscopy while monitoring only molecular ion time-of-flight mass spectrometer, cold sharp spectra are...
We demonstrate the existence of an interfacial barrier in blocked impurity band (BIB) detectors using temperature-dependent dark current and corresponding theoretical calculations. Considering effects barrier, calculated photoresponse is good agreement with experimental results. A dual-excitation model, including direct excitation over full to minimum subsequent tunneling into blocking layer, proposed quantitatively explain observed extension. concept extended-mode detection developed...
In this paper, a single-pixel hyperspectral imager is developed based on the Hadamard transformation. The imager's design, fabrication, signal processing method, and experimental results are discussed. works in pushbroom mode employs both spatial encoding spectral to acquire data cube. patterns, which known for their multiplexing advantage achieve high signal-to-noise ratio (SNR), used schemes. A digital micromirror device (DMD) from Texas Instruments (TI) slow resonant scanning mirror...
We present improved AlGaN solar-blind avalanche photodiodes (APDs) with a separate absorption and multiplication (SAM) structure by introducing polarization electric field the same direction as reverse bias in region. This can be realized reducing Al composition of p-AlGaN layer conventional p-i-n-i-n SAM-APD structure. After employing reduced-Al-composition instead commonly used p-AlGaN, enhanced APD exhibits markedly lower breakdown voltage near two times higher gain up to 2.1 × 10 <sup...
In this study, the solid-state forms and phase transformation of tetrandrine (Tet) were investigated characterized using X-ray diffraction thermal analysis.
Pulsed laser desorption is used as a means of volatilizing thermally labile tyrosine-containing dipeptides for entrainment into supersonic jet expansion. The expansion provides ultracold molecules whose spectral features are probed by resonant two-photon ionization (R2PI) spectroscopy in time-of-flight mass spectrometer. In the studied, contours ∼1.5 nm FWHM observed. Although no sharp were obtained, shape contour quite distinctive, and isomeric can be distinguished. addition, ions produced...
The copolymerization of styrene/1,3-butadiene in emulsion was monitored in-line using an ATR-FTIR spectroscopic probe. concentration monomers to provide real-time conversion and copolymer composition data. Traditional off-line techniques, gravimetry 1H-NMR spectroscopy, were compared the A multivariate calibration method full reaction spectra displayed no significant differences between data sets at a 95% confidence level. It demonstrated that spectroscopy is reliable tool for monitoring...
We describe a microspot matrix-assisted laser desorption ionization (MALDI) mass spectrometric approach to analyze gel-separated phosphoproteins. This method involves in-gel digestion of phosphoproteins after gel separation, followed by open tubular capillary (OTC) immobilized metal-ion affinity chromatography (IMAC) capture the phosphopeptides with markedly reduced interferences from nonphosphorylated peptides. Nanoliter-volume ammonium phosphate is used elute captured on tube. After mixing...
A novel concept of on-chip Fourier transform spectrometer is proposed. It consists semiconductor waveguide directional couplers and NEMS actuators. The optical path difference can be tuned by controlling the actuators to couple or decouple couplers. With 9 stages couplers, we demonstrate numerically that spectral resolution reach up 4 nm in 1.5 μm 1.8 wavelength range. Further enhancement achieved increasing number integrated driven This design meets requirement small size, weight power may...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTContinuous-Flow MALDI Mass Spectrometry Using an Ion Trap/Reflectron Time-of-Flight DetectorLing. He, Li. Liang, and David M. LubmanCite this: Anal. Chem. 1995, 67, 22, 4127–4132Publication Date (Print):November 15, 1995Publication History Published online1 May 2002Published inissue 15 November 1995https://pubs.acs.org/doi/10.1021/ac00118a015https://doi.org/10.1021/ac00118a015research-articleACS PublicationsRequest reuse permissionsArticle...
A novel structure to achieve long wavelength infrared broadband detection ranging from 7.6–10.4 µm is proposed via quantum cascade detector. With a pair of identical coupled wells separated by thin barrier, acting as absorption regions, the relative linewidth (ΔE/E) response can be dramatically broadened 30.7%. Moreover, this introduces about 30% enhancement in blackbody responsivity. It shown that spectral shape tuned bias voltage effectively, while it insensitive working temperature. The...
The cut-off wavelength is one of the most important indicators for infrared detectors, and manipulation always an demand in application long detection. Traditional approaches to extension would inevitably change electronic states devices lead a large increase dark current, which usually causes performance degradations. Here, we demonstrate optical method by plasmonic microcavities with current being unchanged. We fabricate pixel-level single quantum well sandwiched microcavity manipulate...