A5056459714- Urinary Bladder and Prostate Research
- Pelvic floor disorders treatments
- Prostate Cancer Diagnosis and Treatment
- Urinary Tract Infections Management
- Autophagy in Disease and Therapy
- Cancer-related molecular mechanisms research
- Hormonal and reproductive studies
- Thermal Regulation in Medicine
- Kidney Stones and Urolithiasis Treatments
- Pediatric Urology and Nephrology Studies
- Medicinal Plant Pharmacodynamics Research
- Prostate Cancer Treatment and Research
- Sexual function and dysfunction studies
- Anesthesia and Pain Management
- Mechanisms of cancer metastasis
- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Healthcare and Venom Research
- Ubiquitin and proteasome pathways
- Wnt/β-catenin signaling in development and cancer
- Ureteral procedures and complications
- Advanced Causal Inference Techniques
- Chronic Kidney Disease and Diabetes
- Intravenous Infusion Technology and Safety
- Lipid metabolism and biosynthesis
Capital Medical University
2010-2024
Beijing Tongren Hospital
2010-2024
Capital University
2020
Tongren Hospital
2020
Shanghai Medical Information Center
2014
Racial/ethnic disparities in prostate cancer are reported the United States (US). However, long-term trends and contributors of racial/ethnic all-cause cause-specific death among patients with remain unclear. We analysed survivors according to cause US over 25 years.In this retrospective, population-based longitudinal cohort study, we identified diagnosed first primary between 1995 2019, follow-up until Dec 31, using registries' data from Surveillance, Epidemiology, End Results (SEER)...
Emerging preclinical evidence suggests a critical role for androgen-mediated androgen receptor (AR) signaling in bladder cancer progression. However, researchers have not determined whether autophagy modulates the efficacy of an enzalutamide (ENZ) treatment subjects with advanced cancer. In this study, we investigated synergistic effect ENZ and inhibitors on was used as anti-AR drug, chloroquine (CQ), 3-methyladenine (3-MA), bafilomycin A1 (BAF) were inhibitors. J82, T24, UMUC3 cell lines...
Objective To examine the association of kidney stones with new‐onset hypertension, diabetes and obesity. Participants Methods This prospective cohort study included participants in Qingdao Port Cardiovascular Health Study who were aged ≥18 years had abdominal ultrasonography results 2013 that negative for stones. Multivariable Cox regression models time‐dependent covariates used to estimate effects obesity on incidence Results There 9667 without (mean age 46.2 years; 75.6% men). During a...
The dysregulation of androgen receptor (AR) signaling is a critical event in the progression prostate cancer (PCa) and hormone therapy consisting deprivation (ADT) or AR inhibition therefore used to treat advanced cases.It known that N-cadherin becomes upregulated following ADT can directly induce PCa transformation castration-resistant stage (CRPC).However, relationship between unclear may promote better understanding CRPC pathogenesis progression.Here, we demonstrate new axis...
Abstract Introduction Type 2 diabetes mellitus erectile dysfunction (T2DMED) is one of the common complications type (T2DM). Icariside II (ICA II), a flavonoid derived from Epimedium, has been shown to improve function in T2DMED rats. Aim To investigate effect ICA and metformin (MET) on penile function, mitochondrial autophagy, glucose-lipid metabolism rats with T2DMED. Methods In control groups, were administered normal saline. MET group, for 0.2 g/kg/day. II+MET 10 mg/kg/day Results The...
Introduction: The flavonol glycoside icariside II (ICA II) has been shown to exhibit a range of anti-tumor properties. Herein, we evaluated the impact ICA on human prostate cancer cell proliferation, motility, and autophagy, further molecular mechanisms underlying these effects. Methods: We treated DU145 cells with doses then assessed their proliferation via CCK-8 assay, while flow cytometry was used monitor apoptosis cycle progression. utilized wound healing transwell assays probe migration...
Benign prostatic hyperplasia (BPH) is a common chronic progressive disease resulting in urinary obstruction aging men. It comes to more and patients with massive BPH the of society extension life expectancy.The aim study was compare clinical efficacy, safety, complications between transurethral bipolar plasmakinetic enucleation prostate (PKEP) resection (TURP) treatment BPH.Patients were divided into PKEP group TURP randomly. Intraoperative blood loss (BL), operation time (OT), resected...
Abstract Background This study aimed to assess whether urethral pain can be alleviated by urination in male patients undergoing flexible cystoscopy. Methods Ninety-six outpatients cystoscopy were randomly divided into two groups. Patients the test group urinated during cystoscopy, whilst control received no instructions do so. All 10 mL of 2% lidocaine gel prior assessment. Using 0 (no-pain) (unbearable severe pain) scores (VAS), we assessed patient discomfort anesthesia perfusion...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Zheng Y, Wu J, Chen S, Liu Zhang G. Predicting pubic arch interference in permanent prostate brachytherapy based on the specific parameters derived from nuclear magnetic resonance imaging. Journal of Contemporary Brachytherapy. 2018;10(5):405-410. doi:10.5114/jcb.2018.79247. APA Zheng, Y., Wu, J., Chen, S., Liu, & Zhang, (2018). Brachytherapy, 10(5), 405-410. https://doi.org/10.5114/jcb.2018.79247 Chicago...
To study the feasibility of ultrasonography (US) as a replacement for CT during diagnosis ureteral calculi (UC).Clinical and imaging data patients with UC between January 2013 December 2017 were retrospectively analyzed. According to method, divided into 3 groups: Group A, alone; B, US, C, US alone. Age, location, size stones compared among groups. maximum diameter (MD) measured by using in subdivided groups (subgroup 1-3): MD <0.5 cm, 0.5 cm ≤ ≤1.0 >1.0 cm. The subgroups.A total 1,289...
To the Editor: Renal calculi affect 10–15% of adults, and large stones can cause pain potential kidney damage.[1] Nephrolithotomy is primary treatment for over two centimeters, previously managed by open surgery, which caused significant pain, blood loss, long hospital stays.[2] Percutaneous nephrolithotomy (PCNL) a minimally invasive procedure, offering reduced shorter recovery, fewer complications. However, it requires precise renal puncture specialized training due to complex anatomy.[3]...
Abstract Objective: This study aimed to assess whether urethral pain can be alleviated by urination in male patients undergoing flexible cystoscopy. Patient and Methods: Ninety-six outpatients cystoscopy were randomly divided into two groups. Patients the test group urinated during cystoscopy, whilst control received no instructions do so. All 10mL of 2% lidocaine gel prior assessment. Using 0 (no-pain) 10 (unbearable severe pain) scores (VAS), we assessed patient discomfort anesthesia...
Abstract Background: Kidney renal clear cell carcinoma (KIRC), as the most common type of cancer, has a high mortality and recurrence rate due to fact that many patients are in advanced stage at time consultation. Finding biological marker for early-stage KIRC become top priority. Recently, accumulating studies have shown lncRNA can serve target diagnosis prognosis malignancy. However, involvement mechanism linc00342 never been researched KIRC. The aim this study was investigate diagnostic...
Abstract Background The flavonol glycoside icariside Ⅱ (ICA II) has been shown to exhibit a range of anti-tumor properties. Herein we evaluated the impact ICA II on proliferation, motility, and autophagy activity human prostate cancer cells, further molecular mechanisms underlying these effects. Methods Herein, treated DU145 cells with doses. We then proliferative abilities via CCK-8 assay, whereas apoptosis cell cycle status were assessed flow cytometry. utilized wound healing transwell...
Innovative education is the strong requirement of times and medical development.We changed traditional teaching method,and instead used problem-based learning evidence-based medicine model in surgical clinical teaching.The new can effectively train undergraduate thinking,cultivate abilities deconstructing problem,comprehensive analysis,literature retrieval,language expression,exploration innovation.Medical students will benefit from integration EBM PBL.This help them not only understand...
Objective To study the role of B-mode ultrasound found bladder trabeculation in evaluating degree outlet obstruction (BOO) and function benign prostatic hyperplasia (BPH) patients.Methods Conducted prospective research to determine differences clinical data urodynamic parameters between BPH patients with without diagnosed by abdominal ultrasound.Results Thirty-six were compared 68 trabeculation.The mean age was (73.7 ± 10.1 ) years for ( 69.6 6.2 trabeculation, IPSS 24.4 6.6 22.8 8.3...
Background: Racial/ethnic disparities in prostate cancer are reported the United States (US). However, long-term trends and contributors of racial/ethnic all-cause cause-specific death among patients with remain unclear. We analysed survivors according to cause US over 25 years.Methods: In this retrospective, population-based longitudinal cohort study, we identified diagnosed first primary between 1995 2019, follow-up through Dec using registries’ data from Surveillance, Epidemiology, End...