Login

Qianming Du

ORCID: 0000-0003-3510-1373
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
A5014804555
Research Areas
  • Cancer, Stress, Anesthesia, and Immune Response
  • Advanced Breast Cancer Therapies
  • Diet, Metabolism, and Disease
  • IL-33, ST2, and ILC Pathways
  • Infant Nutrition and Health
  • Epigenetics and DNA Methylation
  • Protein Tyrosine Phosphatases
  • Ubiquitin and proteasome pathways
  • Pediatric health and respiratory diseases
  • Cancer, Lipids, and Metabolism
  • Endometriosis Research and Treatment
  • Cancer, Hypoxia, and Metabolism
  • Cancer Cells and Metastasis
  • Receptor Mechanisms and Signaling

China Pharmaceutical University
 2024-2025

Nanjing Medical University
 2024-2025

University of Pittsburgh
 2013

 Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1–ZEB1 Axis–Mediated Epithelial–Mesenchymal Transition
OPENALEX - Publications 
Tao Li Lei Wei Xin Zhang Bin Fu Yunjiang Zhou and 9 more Mengdi Yang Mengran Cao Yaxin Chen Yingying Tan Yongwei Shi Leyin Wu Chenyuan Xuan Qianming Du Rong Hu

A number of neurotransmitters have been detected in tumor microenvironment and proved to modulate cancer oncogenesis progression. We previously found that biosynthesis secretion neurotransmitter 5-hydroxytryptamine (5-HT) was elevated colorectal cells. In this study, we discovered the HTR2B receptor 5-HT highly expressed tissues, which further identified as a strong risk factor for prognostic outcomes. Both pharmacological blocking genetic knocking down impaired migration cell, well...

10.1158/1541-7786.mcr-23-0513 article EN Molecular Cancer Research 2024-02-21
 SERPINH1 secretion by cancer-associated fibroblasts promotes hepatocellular carcinoma malignancy through SENP3-mediated SP1/SQLE pathway
OPENALEX - Publications 
Hua Xiao Zhaoying Yao Tao Li Xin Fang Xuejiao Xu and 6 more Sheng Hu Ya Yang Chenchen Jin Yuxiang Fei Chao Liu Qianming Du

10.1016/j.intimp.2025.114259 article EN International Immunopharmacology 2025-02-12
 SHP2‐Triggered Endothelial Cell Activation Fuels Estradiol‐Independent Endometrial Sterile Inflammation
OPENALEX - Publications 
Jie Pan Jiao Qu Fang Wen Lixin Zhao Wei Zheng and 6 more Linhui Zhai Minjia Tan Qiang Xu Qianming Du Wen Lv Yang Sun

Abstract Sterile inflammation occurs in various chronic diseases due to many nonmicrobe factors. Examples include endometrial hyperplasia (EH), endometriosis, cancer, and breast which are all sterile induced by estrogen imbalances. However, how estrogen‐induced regulates EH remains unclear. Here, a single‐cell RNA‐Seq is used show that SHP2 upregulation endothelial cells promotes their inflammatory activation subsequent transendothelial macrophage migration. Independent of the initial...

10.1002/advs.202403038 article EN cc-by Advanced Science 2024-09-05
 Data from Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1–ZEB1 Axis–Mediated Epithelial–Mesenchymal Transition
OPENALEX - Publications 
Tao Li Lei Wei Xin Zhang Bin Fu Yunjiang Zhou and 9 more Mengdi Yang Mengran Cao Yaxin Chen Yingying Tan Yongwei Shi Leyin Wu Chenyuan Xuan Qianming Du Rong Hu

<div>Abstract<p>A number of neurotransmitters have been detected in tumor microenvironment and proved to modulate cancer oncogenesis progression. We previously found that biosynthesis secretion neurotransmitter 5-hydroxytryptamine (5-HT) was elevated colorectal cells. In this study, we discovered the HTR2B receptor 5-HT highly expressed tissues, which further identified as a strong risk factor for prognostic outcomes. Both pharmacological blocking genetic knocking down impaired...

10.1158/1541-7786.c.7267998 preprint EN 2024-06-04
 Supplementary Figure S11 from Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1–ZEB1 Axis–Mediated Epithelial–Mesenchymal Transition
OPENALEX - Publications 
Tao Li Lei Wei Xin Zhang Bin Fu Yunjiang Zhou and 9 more Mengdi Yang Mengran Cao Yaxin Chen Yingying Tan Yongwei Shi Leyin Wu Chenyuan Xuan Qianming Du Rong Hu

<p>This file contains Supplementary Figure S11 and its legend.</p>

10.1158/1541-7786.25964919 preprint EN cc-by 2024-06-04
 Supplementary Figure S14 from Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1–ZEB1 Axis–Mediated Epithelial–Mesenchymal Transition
OPENALEX - Publications 
Tao Li Lei Wei Xin Zhang Bin Fu Yunjiang Zhou and 9 more Mengdi Yang Mengran Cao Yaxin Chen Yingying Tan Yongwei Shi Leyin Wu Chenyuan Xuan Qianming Du Rong Hu

<p>This file contains Supplementary Figure S14 and its legend.</p>

10.1158/1541-7786.25964907.v1 preprint EN cc-by 2024-06-04
 Supplementary Figure S9 from Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1–ZEB1 Axis–Mediated Epithelial–Mesenchymal Transition
OPENALEX - Publications 
Tao Li Lei Wei Xin Zhang Bin Fu Yunjiang Zhou and 9 more Mengdi Yang Mengran Cao Yaxin Chen Yingying Tan Yongwei Shi Leyin Wu Chenyuan Xuan Qianming Du Rong Hu

<p>This file contains Supplementary Figure S9 and its legend.</p>

10.1158/1541-7786.25964862.v1 preprint EN cc-by 2024-06-04
 Supplementary Figure S4 from Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1–ZEB1 Axis–Mediated Epithelial–Mesenchymal Transition
OPENALEX - Publications 
Tao Li Lei Wei Xin Zhang Bin Fu Yunjiang Zhou and 9 more Mengdi Yang Mengran Cao Yaxin Chen Yingying Tan Yongwei Shi Leyin Wu Chenyuan Xuan Qianming Du Rong Hu

<p>This file contains Supplementary Figure S4 and its legend.</p>

10.1158/1541-7786.25964877.v1 preprint EN cc-by 2024-06-04
 Supplementary Figure S13 from Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1–ZEB1 Axis–Mediated Epithelial–Mesenchymal Transition
OPENALEX - Publications 
Tao Li Lei Wei Xin Zhang Bin Fu Yunjiang Zhou and 9 more Mengdi Yang Mengran Cao Yaxin Chen Yingying Tan Yongwei Shi Leyin Wu Chenyuan Xuan Qianming Du Rong Hu

<p>This file contains Supplementary Figure S13 and its legend.</p>

10.1158/1541-7786.25964910.v1 preprint EN cc-by 2024-06-04
 Supplementary Figure S20 from Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1–ZEB1 Axis–Mediated Epithelial–Mesenchymal Transition
OPENALEX - Publications 
Tao Li Lei Wei Xin Zhang Bin Fu Yunjiang Zhou and 9 more Mengdi Yang Mengran Cao Yaxin Chen Yingying Tan Yongwei Shi Leyin Wu Chenyuan Xuan Qianming Du Rong Hu

<p>This file contains Supplementary Figure S20 and its legend.</p>

10.1158/1541-7786.25964883.v1 preprint EN cc-by 2024-06-04
 Supplementary Figure S10 from Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1–ZEB1 Axis–Mediated Epithelial–Mesenchymal Transition
OPENALEX - Publications 
Tao Li Lei Wei Xin Zhang Bin Fu Yunjiang Zhou and 9 more Mengdi Yang Mengran Cao Yaxin Chen Yingying Tan Yongwei Shi Leyin Wu Chenyuan Xuan Qianming Du Rong Hu

<p>This file contains Supplementary Figure S10 and its legend.</p>

10.1158/1541-7786.25964922.v1 preprint EN cc-by 2024-06-04
 Supplementary Figure S1 from Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1–ZEB1 Axis–Mediated Epithelial–Mesenchymal Transition
OPENALEX - Publications 
Tao Li Lei Wei Xin Zhang Bin Fu Yunjiang Zhou and 9 more Mengdi Yang Mengran Cao Yaxin Chen Yingying Tan Yongwei Shi Leyin Wu Chenyuan Xuan Qianming Du Rong Hu

<p>This file contains Supplementary Figure S1 and its legend.</p>

10.1158/1541-7786.25964925 preprint EN cc-by 2024-06-04
 Supplementary Figure S18 from Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1–ZEB1 Axis–Mediated Epithelial–Mesenchymal Transition
OPENALEX - Publications 
Tao Li Lei Wei Xin Zhang Bin Fu Yunjiang Zhou and 9 more Mengdi Yang Mengran Cao Yaxin Chen Yingying Tan Yongwei Shi Leyin Wu Chenyuan Xuan Qianming Du Rong Hu

<p>This file contains Supplementary Figure S18 and its legend.</p>

10.1158/1541-7786.25964895.v1 preprint EN cc-by 2024-06-04
 Supplementary Figure S15 from Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1–ZEB1 Axis–Mediated Epithelial–Mesenchymal Transition
OPENALEX - Publications 
Tao Li Lei Wei Xin Zhang Bin Fu Yunjiang Zhou and 9 more Mengdi Yang Mengran Cao Yaxin Chen Yingying Tan Yongwei Shi Leyin Wu Chenyuan Xuan Qianming Du Rong Hu

<p>This file contains Supplementary Figure S15 and its legend.</p>

10.1158/1541-7786.25964904.v1 preprint EN cc-by 2024-06-04
 Supplementary Figure S16 from Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1–ZEB1 Axis–Mediated Epithelial–Mesenchymal Transition
OPENALEX - Publications 
Tao Li Lei Wei Xin Zhang Bin Fu Yunjiang Zhou and 9 more Mengdi Yang Mengran Cao Yaxin Chen Yingying Tan Yongwei Shi Leyin Wu Chenyuan Xuan Qianming Du Rong Hu

<p>This file contains Supplementary Figure S16 and its legend.</p>

10.1158/1541-7786.25964901.v1 preprint EN cc-by 2024-06-04
 Supplementary Figure S5 from Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1–ZEB1 Axis–Mediated Epithelial–Mesenchymal Transition
OPENALEX - Publications 
Tao Li Lei Wei Xin Zhang Bin Fu Yunjiang Zhou and 9 more Mengdi Yang Mengran Cao Yaxin Chen Yingying Tan Yongwei Shi Leyin Wu Chenyuan Xuan Qianming Du Rong Hu

<p>This file contains Supplementary Figure S5 and its legend.</p>

10.1158/1541-7786.25964874.v1 preprint EN cc-by 2024-06-04
 Supplementary Figure S11 from Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1–ZEB1 Axis–Mediated Epithelial–Mesenchymal Transition
OPENALEX - Publications 
Tao Li Lei Wei Xin Zhang Bin Fu Yunjiang Zhou and 9 more Mengdi Yang Mengran Cao Yaxin Chen Yingying Tan Yongwei Shi Leyin Wu Chenyuan Xuan Qianming Du Rong Hu

<p>This file contains Supplementary Figure S11 and its legend.</p>

10.1158/1541-7786.25964919.v1 preprint EN cc-by 2024-06-04
 Supplementary Figure S7 from Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1–ZEB1 Axis–Mediated Epithelial–Mesenchymal Transition
OPENALEX - Publications 
Tao Li Lei Wei Xin Zhang Bin Fu Yunjiang Zhou and 9 more Mengdi Yang Mengran Cao Yaxin Chen Yingying Tan Yongwei Shi Leyin Wu Chenyuan Xuan Qianming Du Rong Hu

<p>This file contains Supplementary Figure S7 and its legend.</p>

10.1158/1541-7786.25964868.v1 preprint EN cc-by 2024-06-04
 Supplementary Figure S1 from Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1–ZEB1 Axis–Mediated Epithelial–Mesenchymal Transition
OPENALEX - Publications 
Tao Li Lei Wei Xin Zhang Bin Fu Yunjiang Zhou and 9 more Mengdi Yang Mengran Cao Yaxin Chen Yingying Tan Yongwei Shi Leyin Wu Chenyuan Xuan Qianming Du Rong Hu

<p>This file contains Supplementary Figure S1 and its legend.</p>

10.1158/1541-7786.25964925.v1 preprint EN cc-by 2024-06-04
 Supplementary Figure S8 from Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1–ZEB1 Axis–Mediated Epithelial–Mesenchymal Transition
OPENALEX - Publications 
Tao Li Lei Wei Xin Zhang Bin Fu Yunjiang Zhou and 9 more Mengdi Yang Mengran Cao Yaxin Chen Yingying Tan Yongwei Shi Leyin Wu Chenyuan Xuan Qianming Du Rong Hu

<p>This file contains Supplementary Figure S8 and its legend.</p>

10.1158/1541-7786.25964865.v1 preprint EN cc-by 2024-06-04
 Supplementary Figure S17 from Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1–ZEB1 Axis–Mediated Epithelial–Mesenchymal Transition
OPENALEX - Publications 
Tao Li Lei Wei Xin Zhang Bin Fu Yunjiang Zhou and 9 more Mengdi Yang Mengran Cao Yaxin Chen Yingying Tan Yongwei Shi Leyin Wu Chenyuan Xuan Qianming Du Rong Hu

<p>This file contains Supplementary Figure S17 and its legend.</p>

10.1158/1541-7786.25964898.v1 preprint EN cc-by 2024-06-04
 Supplementary Figure S12 from Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1–ZEB1 Axis–Mediated Epithelial–Mesenchymal Transition
OPENALEX - Publications 
Tao Li Lei Wei Xin Zhang Bin Fu Yunjiang Zhou and 9 more Mengdi Yang Mengran Cao Yaxin Chen Yingying Tan Yongwei Shi Leyin Wu Chenyuan Xuan Qianming Du Rong Hu

<p>This file contains Supplementary Figure S12 and its legend.</p>

10.1158/1541-7786.25964916.v1 preprint EN cc-by 2024-06-04
Coming Soon ...