A5089134662- Spondyloarthritis Studies and Treatments
- Systemic Lupus Erythematosus Research
- Health disparities and outcomes
- Rheumatoid Arthritis Research and Therapies
- Inflammasome and immune disorders
- Climate Change and Health Impacts
- Autoimmune and Inflammatory Disorders Research
- Psoriasis: Treatment and Pathogenesis
- Global Public Health Policies and Epidemiology
- Retinal Imaging and Analysis
- Macrophage Migration Inhibitory Factor
- Cytokine Signaling Pathways and Interactions
- Pulmonary Hypertension Research and Treatments
- Cardiovascular Health and Risk Factors
- T-cell and B-cell Immunology
- Child and Adolescent Psychosocial and Emotional Development
- Atherosclerosis and Cardiovascular Diseases
- Pneumonia and Respiratory Infections
- Healthcare Systems and Public Health
- Vitamin D Research Studies
- Mental Health Treatment and Access
- Inflammatory Biomarkers in Disease Prognosis
- Urinary Bladder and Prostate Research
- Bone and Joint Diseases
- Blood Pressure and Hypertension Studies
Anhui Medical University
2016-2025
Second Hospital of Anhui Medical University
2022-2024
University of Washington
2023-2024
Institute for Health Metrics and Evaluation
2023-2024
University of Electronic Science and Technology of China
2023
Anhui Provincial Center for Disease Control and Prevention
2016
Depression, anxiety and schizophrenia among older persons have become global public health challenges. However, the burden of these disorders in ageing aged countries has not been analysed.
Objective Chronic kidney disease (CKD) poses a major global health burden. Early CKD risk prediction enables timely interventions, but conventional models have limited accuracy. Machine learning (ML) enhances prediction, interpretability is needed to support clinical usage with both in diagnostic and decision-making. Methods A cohort of 491 patients data was collected for this study. The dataset randomly split into an 80% training set 20% testing set. To achieve the first objective, we...
Identify long non-coding RNAs (lncRNAs) that might serve as biomarkers for systemic lupus erythematosus (SLE) and explore the biological functions of identified lncRNAs. In screening phase, we examined lncRNA expression profile plasma samples from 24 patients with SLE 12 healthy controls (HCs) using microarray pooled samples. The candidate lncRNAs were verified in individual by quantitative real-time (qRT)-PCR. independent validation stage, evaluated 240 120 HCs. assessed further an external...
BACKGROUND:To explore the significance of short message service (SMS) on management pulmonary tuberculosis (TB) patients in reinforcing treatment adherence and health awareness, provide scientific evidences for popularizing this model formulating related polices measures. MATERIAL AND METHODS:Six counties (districts) were selected by stratified cluster sampling method, randomly divided into control group intervention group. Pulmonary TB eligible to study criteria included study. SMS regular...
Objectives To estimate the global burden of malaria and neglected tropical diseases (NTDs) in children adolescents aged 0–19 years to analyse trends inform public health policy decisions. Design Population-based, cross-sectional study. Setting Global analysis across 204 countries territories. Participants Children with NTDs, stratified by age, gender location from 1990 2019. Main outcome measures Yearly incidence, prevalence, disability-adjusted life (DALYs) for age-standardised incidence...
Neglected Tropical Diseases (NTDs) and malaria present considerable health obstacles, particularly impacting the socio-economic progress in at-risk areas. We aimed to estimate burden, trends, inequalities of NTDs globally, regionally, nationally from 1990 2021. The study utilized data Global Burden Diseases, Injuries, Risk Factors Study (GBD) 2021, encompassing 204 countries territories, spanning 21 global regions, including diverse populations across different Socio-Demographic Index (SDI)...
Abstract Prostate cancer (PCa), a severe health burden for males, accounts the second frequent and fifth tumor specific death around world. Several studies on tumor‐infiltrating immune cells (TIICs) have shown inconsistent controversial results to PCa. We downloaded gene expression matrix clinical information from TCGA, CIBERSORT was used identify proportion of TIICs. Wilcoxon's Sign Rank Test evaluated different levels in PCa normal tissues. Kaplan‐Meier curves were evaluate associations...
Long non-coding RNA (lncRNA) H19 is associated with inflammatory diseases, but the molecular mechanism of in process ankylosing spondylitis (AS) unclear. Here, we investigated role and its downstream molecules inflammation AS by microarray analysis, qRT-PCR, western blot, dual-luciferase reporter assay. small interfering (siRNA) (Si-H19) adenovirus (AD-H19) were used to decrease increase expression, respectively. 42 annotated lncRNAs identified, was overexpressed. H19, vitamin D receptor...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron (B.1.1.529) variant is highly transmissible with potential immune escape. Hence, control measures are continuously being optimized to guard against large-scale disease 2019 (COVID-19) outbreaks. This study aimed explore the relationship between intensity of in response different SARS-CoV-2 variants and degree outbreak at city level.
Myocarditis and cardiomyopathy are commonly occurring cardiovascular diseases that seriously threaten children's health. It was urgent to update the global incidence mortality of childhood myocarditis cardiomyopathy, predict rate 2035 by Global Burden Disease database.The study data from 1990 2019 in 204 countries territories were used determine: rates 0 19 five age groups; relationship between sociodemographic index (SDI) group; and, based on an age-period-cohort model, projected for...