A5083897796- Obesity, Physical Activity, Diet
- Digital Mental Health Interventions
- Mental Health Research Topics
- Obesity and Health Practices
- Eating Disorders and Behaviors
- Nutritional Studies and Diet
- Mental Health Treatment and Access
- Diet and metabolism studies
- Schizophrenia research and treatment
- Birth, Development, and Health
- Smoking Behavior and Cessation
- Tryptophan and brain disorders
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Research in Social Sciences
- Genetic Associations and Epidemiology
- Psychotherapy Techniques and Applications
- Cardiovascular Disease and Adiposity
- Obsessive-Compulsive Spectrum Disorders
- Bipolar Disorder and Treatment
- Psychiatric care and mental health services
- Bariatric Surgery and Outcomes
- Telemedicine and Telehealth Implementation
- Impact of Technology on Adolescents
- Maternal Mental Health During Pregnancy and Postpartum
- Metabolomics and Mass Spectrometry Studies
Helsinki University Hospital
2008-2025
Tampere University
2025
Päijät-Hämeen Keskussairaala
2025
University of Helsinki
2008-2024
Hospital District of Helsinki and Uusimaa
2019-2020
Finnish Institute for Health and Welfare
2009-2018
Turku University Hospital
2014-2018
University of Turku
2018
Varsinais-Suomen Sairaanhoitopiiri
2016
National Institutes of Health
2010-2013
Body mass index (BMI), a simple anthropometric measure, is the most frequently used measure of adiposity and has been instrumental in documenting worldwide increase prevalence obesity witnessed during last decades. Although this overweight thought to be mainly due environmental changes, i.e., sedentary lifestyles high caloric diets, consistent evidence from twin studies demonstrates heritability importance genetic differences for normal variation BMI. We analysed self-reported data on BMI...
Abstract Background Persons with schizophrenia and other psychotic disorders have a high prevalence of obesity, impaired glucose tolerance, lipid abnormalities, particularly hypertriglyceridemia low high-density lipoprotein. More detailed molecular information on the metabolic abnormalities may reveal clues about pathophysiology these changes, as well disease specificity. Methods We applied comprehensive metabolomics in serum samples from general population-based study Finland. The included...
Symptoms of depression and anxiety frequently co-occur, but traditional discrete-time models fail to capture their causal interactions. To explore the dynamic relationship between these symptoms, we applied two advanced methodologies—non-Gaussian direction dependence analyses continuous-time structural equation modeling—across therapist-guided internet-based cognitive-behavioral therapy (iCBT) samples general-population cohorts ( N = 22,530). Our findings revealed that in iCBT, neither nor...
Maternal prenatal symptoms of depression and anxiety have been suggested to impose differential effects on later offspring development, depending their characteristics, such as timing, intensity persistence. Paternal less investigated. While knowledge these trajectory characteristics is essential for improved comprehension stress, prospective studies including both expecting parents scarce. We aim at identifying comparing the trajectories depressive in a pregnancy cohort design. The sample...
Objectives. We studied the association of adolescent smoking with overweight and abdominal obesity in adulthood. Methods. used FinnTwin16, a prospective, population-based questionnaire study 5 consecutive complete birth cohorts Finnish twins born between 1975 1979 (N = 4296) at four points ages 16 27 years to analyze effect on early Results. Smoking least 10 cigarettes daily when aged 18 increased risk adult (odds ratio [OR]=1.77; 95% confidence interval [CI] 1.39, 2.26). After we adjusted...
We investigated mortality and its determinants in people with psychotic disorder.A nationally representative two-stage cluster sample of 8028 persons aged 30 years or older from Finland was selected for a comprehensive health survey conducted 2000 to 2001. Participants were screened disorder, screen-positive invited Structured Clinical Interview DSM-IV. The diagnostic assessment DSM-IV disorders based on the DSM-IV, case records mental treatments, both. Mortality followed up until September...
<sec> <title>BACKGROUND</title> Internet-based cognitive behavioral therapies (iCBTs) fall into two categories, therapist-assisted and self-guided iCBTs have amassed substantial evidence for cost-effectiveness effectiveness in treating various mental health conditions. Lower drop-out rates are seen compared to treatments. However, relatively high treatment dropout rates, especially the iCBTs, indicate that some level of therapist assistance is needed curb rates. In-depth understanding on why...
Objective: Internet-delivered cognitive behavior therapies (iCBT) are effective and scalable treatments for depression anxiety. However, treatment adherence remains a major limitation that could be further understood by applying machine learning methods to during-treatment messages. We used learned topics predict drop-out risk symptom change in iCBT. Method: applied topic modeling naturalistic messages from 18,117 patients of nationwide iCBT programs generalized anxiety disorder (GAD)....
Background The literature suggests an association between obesity and schizophrenia but fat mass fat-free mass, which have been shown to be more predictive of all-cause mortality than only waist circumference [body index (BMI) ⩾30 kg/m 2 ], not reported in psychotic disorders. We examined the detailed body composition people with different disorders a large population-based sample. Method used nationally representative sample 8082 adult Finns aged years measured anthropometrics (height,...
The aim of the present study was to compare lifestyle (leisure-time physical activity, smoking habits and alcohol consumption) dietary (energy-yielding nutrients, fibre foods) factors Finns with a new syndrome called normal-weight obesity (NWO) those lean overweight Finns. representative population-based included 4786 participants (25–74 years) from National FINRISK 2007 Study health examination questionnaires. Food intake assessed using validated FFQ. NWO defined include normal BMI ( <...
Several studies have reported direct associations of smoking with body mass index (BMI) and abdominal obesity. However, the interplay between them is poorly understood. Our first aim was to investigate interaction status BMI on obesity (waist circumference, WC). second examine how association WC varies among normal overweight/obese men women. We examined 5817 participants from National FINRISK 2007 Study. The interactions were analyzed. Participants categorized into eight groups according...
Background: This study investigated the epidemiology of eating disorders in a population-based sample young adults. Method: A mental health questionnaire was sent to nationally representative two-stage cluster 1863 Finns aged 20–35 years. All screen-positives and random screen-negatives were invited participate Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) interview. Case records from all lifetime treatments also obtained used complement diagnostic assessment. Results:...
Complementing the development of evidence-based psychological therapies, practice-based evidence has developed from patient samples collected in routine care, addressing questions relevant to patients and practitioners, thereby expanding our knowledge therapies their impact. Implementation assessments care allows for timely clinical decision support collection multiple data sets by needs clinicians (e.g., outcome monitoring) researchers identifying impact therapist variables on outcomes).
We tested the validity of SCOFF, a five-question screening instrument for eating disorders, in general population sample.A random sample 1863 Finnish young adults was approached with questionnaire that contained several screens mental health interview, including SCOFF. The returned by 1316 persons. All screen positives and negatives were invited to SCID interview. Altogether 541 subjects participated interview had filled SCOFF questionnaire. investigated detecting current disorders...
We introduced methods for solving causal direction of dependence between variables observed in pre- and post-psychotherapy assessments, showing how to apply them investigate their properties via simulations. In addition, we investigated whether changes depressive symptoms drive social occupational functioning as suggested by the phase model psychotherapy or vice versa, neither.As a Gaussian (normal-distribution) is unidentifiable here, used an identifiable linear non-Gaussian structural...
Therapist-supported, internet-delivered cognitive behavioral therapy (iCBT) is efficacious for generalized anxiety disorder (GAD), but few studies are yet to report its effectiveness in routine care.In this study, we aim examine whether a new 12-session iCBT program GAD effective nationwide care.We administered specialized, clinic-delivered, therapist-supported 1099 physician-referred patients. The was free of charge patients, and the completion time not predetermined. We measured symptoms...
Body mass index (BMI), a simple anthropometric measure, is the most frequently used measure of adiposity and has been instrumental in documenting worldwide increase prevalence obesity witnessed during last decades. Although this overweight thought to be mainly due environmental changes, i.e., sedentary lifestyles high caloric diets, consistent evidence from twin studies demonstrates heritability importance genetic differences for normal variation BMI. We analysed self-reported data on BMI...