A5059726683- Maternal Mental Health During Pregnancy and Postpartum
- Child and Adolescent Psychosocial and Emotional Development
- Infant Development and Preterm Care
- Neuroendocrine regulation and behavior
- Neonatal and fetal brain pathology
- Functional Brain Connectivity Studies
- Infant Health and Development
- Child Abuse and Trauma
- Face Recognition and Perception
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Cognitive Abilities and Testing
- Early Childhood Education and Development
- Epilepsy research and treatment
- Neonatal Respiratory Health Research
- Stress Responses and Cortisol
- Advanced Neuroimaging Techniques and Applications
- Child Nutrition and Feeding Issues
- Health, Environment, Cognitive Aging
- Attachment and Relationship Dynamics
- Resilience and Mental Health
- Prenatal Substance Exposure Effects
- Neural and Behavioral Psychology Studies
- Dental Anxiety and Anesthesia Techniques
- Breastfeeding Practices and Influences
- Williams Syndrome Research
University of Turku
2016-2025
Turku University Hospital
2019-2025
Tampere University
2020
Cohort (United Kingdom)
2019
Maternal symptoms of depression and anxiety during pregnancy early postnatal years are suggested to impose differential negative effects on child's socio-emotional development depending the characteristics symptoms, such as timing, intensity, persistence. The aim this study was identify trajectories maternal depressive from until 2 postpartum examine their relationship with child problems competence at 5 age. sample included 1208 mother-infant dyads FinnBrain Birth Cohort study. Latent...
Maternal prenatal symptoms of depression and anxiety have been suggested to impose differential effects on later offspring development, depending their characteristics, such as timing, intensity persistence. Paternal less investigated. While knowledge these trajectory characteristics is essential for improved comprehension stress, prospective studies including both expecting parents scarce. We aim at identifying comparing the trajectories depressive in a pregnancy cohort design. The sample...
Early life experiences have persisting influence on brain function throughout life. Maternal signals constitute a primary source of early experiences, and their quantity quality during sensitive developmental periods exert enduring effects cognitive emotional social behaviors. Here we examined if, in addition to established qualitative dimensions maternal behavior her interactions with infant child, patterns may contribute the maturation children's executive functions. We focused primarily...
Maternal prenatal cortisol levels have been inconsistently associated with self-reports of psychological distress (PD). Previous research has linked hair concentration (HCC) evaluating cumulatively the previous months cross-sectional PD measures that usually cover past week(s), which may lead to misleading conclusions on their relations. We aimed investigate how maternal HCC relates cumulative across pregnancy.Subjects (N = 595) were drawn from FinnBrain Birth Cohort Study. was measured...
Little consideration has been given to the possibility of human infant development being shaped via lactocrine programming, and by breast milk cortisol levels specifically. Despite animal models indicating that glucocorticoid (GC) exposure lactation might modify brain behavior, only one study reported were positively associated with negative affectivity, especially fearfulness sadness-early emerging risk factors for internalizing difficulties such as anxiety. The aim current was investigate...
Prenatal and postnatal maternal psychological distress predicts various detrimental consequences on social, behavioral, cognitive development of offspring, especially in girls. Maturation white matter (WM) continues from prenatal into adulthood is thus susceptible to exposures both before after birth.
Sensitivity to others' emotional signals is an important factor for social interaction. While many studies of reactivity focus on facial expressions, such as pupil dilation which can indicate arousal, may also affect observers. For example, observers' pupils dilate when viewing someone with dilated pupils, so-called pupillary contagion. Yet it unclear how size and expression interact signals. Further, examining individual differences in others shed light its mechanisms potential outcomes. In...
We examined how infants’ attentional disengagement from happy, fearful, neutral, and phase‐scrambled faces at 8 months, as assessed by eye tracking, is associated with trajectories of maternal depressive symptoms early pregnancy to 6 months postpartum (decreasing n = 48, increasing 34, consistently low symptom levels 280). The sample (mother–infant dyads belonging a larger FinnBrain Birth Cohort Study) was collected between 5/2013–6/2016. overall probability distractors not related symptoms,...
Maternal depression and anxiety may endanger well-being of both mother child. We investigated the efficacy probiotics and/or fish oil (FO) in modifying pre- postnatal depressive symptoms. Symptom trajectories were identified influence lifestyle factors on symptoms was evaluated. Overweight women (n = 439) randomized to intervention groups (probiotics+FO, probiotics+placebo, FO+placebo, placebo+placebo) from early pregnancy until six months postpartum, assessed for with Edinburgh Postnatal...
Maternal prenatal distress can participate in the programming of offspring development, which exposure to altered maternal long-term cortisol levels as measured by hair concentrations (HCC) may contribute. Yet, studies investigating whether and how HCC associates with problems child socioemotional development are scarce. Furthermore, questions remain regarding timing potential sex-specificity fetal there interactions distress, such depressive symptoms. The subjects were drawn from those...
The gut microbiota has been suggested to influence neurodevelopment in rodents. Preliminary human studies have associated fecal composition with features of emotional and cognitive development as well differences thalamus-amygdala connectivity. Currently, microbiota-gut-brain axis cover heterogenous set infant child brain developmental phenotypes, while associations more fine-grained aspects remain largely unknown. Here (N = 122, 53% boys), we investigated the between attention faces, bias...
Pediatric neuroimaging is a quickly developing field that still faces important methodological challenges. images usually have more motion artifact than adult images. The can cause visible errors in brain segmentation, and one way to address it manually edit the segmented Variability editing quality control protocols may complicate comparisons between studies. In this article, we describe detail semiautomated segmentation protocol of structural was used FinnBrain Birth Cohort Study relies on...
Developing accurate subcortical volumetric quantification tools is crucial for neurodevelopmental studies, as they could reduce the need challenging and time-consuming manual segmentation. In this study, accuracy of two automated segmentation tools, FSL-FIRST (with three different boundary correction settings) FreeSurfer, were compared against hippocampus nuclei, including amygdala, thalamus, putamen, globus pallidus, caudate nucleus accumbens, using correlation analyses in 80 5-year-olds....
Emerging evidence suggests that exposure to unpredictable patterns of maternal sensory signals during infancy is associated with child neurodevelopment, including poorer effortful control. However, longitudinal effects on development and possible sex differences are understudied. The aims the present study were explore whether related control at 5 years age moderates these associations. In addition, we examined how very high vs. low/moderate unpredictability using categorical cut-offs...
Previous studies report that early life stress, including maternal pre‐ and postnatal has adverse effects on cognitive development these associations might be sex‐specific. However, no exist stress infant executive functioning ( EF ). The aim of this study was to examine the relationship between , whether are moderated by sex. Maternal prenatal depressive, general anxiety, pregnancy‐specific anxiety symptoms were measured three times, depressive 6 months postpartum. Infant assessed with a...
Maternal postpartum depression is a prominent risk factor for aberrant child socioemotional development, but there little understanding about the neural phenotypes that underlie infant sensitivity to maternal depression. We examined whether newborn white matter fractional anisotropy (FA), measure of maturity, moderates association between depressive symptoms and negative reactivity at 6 months. Participants were 80 mother-infant dyads participating in prospective population-based cohort,...
Both patterns of maternal sensory signals and sensitive care have shown to be crucial elements shaping child development. However, research concerning these aspects has focused mainly on sensitivity with fewer studies evaluating the impact behaviors changes in indices across infancy childhood. The aims this study were explore how unpredictability develop associate each other from toddlerhood whether elevated depressive anxiety symptoms relate unpredictable toddlerhood. population consisted...
After 5 months of age, infants begin to prioritize attention fearful over other facial expressions. One key proposition is that amygdala and related early-maturing subcortical network, important for emergence this attentional bias – however, empirical data support these assertions are lacking. In prospective longitudinal study, we measured volumes from MR images in 65 healthy neonates at 2–5 weeks gestation corrected age disengagement vs. non-fearful expressions 8 with eye tracking. Overall,...