A5007223850- Ear Surgery and Otitis Media
- Hearing, Cochlea, Tinnitus, Genetics
- Vestibular and auditory disorders
- Head and Neck Surgical Oncology
- Sinusitis and nasal conditions
- Hearing Loss and Rehabilitation
- Ear and Head Tumors
- Nasal Surgery and Airway Studies
- Connexins and lens biology
- Neuroscience of respiration and sleep
- Reconstructive Surgery and Microvascular Techniques
- Ion Channels and Receptors
- Neural dynamics and brain function
- Facial Nerve Paralysis Treatment and Research
- Sarcoma Diagnosis and Treatment
- Congenital heart defects research
- Electron Spin Resonance Studies
- Full-Duplex Wireless Communications
- Radiation Detection and Scintillator Technologies
- Organ and Tissue Transplantation Research
- Soft tissue tumors and treatment
- bioluminescence and chemiluminescence research
- Metastasis and carcinoma case studies
- Advanced MRI Techniques and Applications
- Hearing Impairment and Communication
Tohoku University
2015-2024
The Sense Innovation and Research Center
2009-2019
Kurume University
2017-2018
Textron Systems (United Kingdom)
2016
Senshio Rifu hospital
2016
Kanagawa Dental University
2013
Kansas State University
2004-2010
Generation of a strong electrical potential in the cochlea is uniquely mammalian and may reflect recent evolutionary advances cellular voltage-dependent amplifiers. This endocochlear hypothesized to dramatically improve hearing sensitivity, concept that difficult explore experimentally, because manipulating cochlear function frequently causes rapid degenerative changes early development. Here, we examine deafness phenotype adult Claudin 11-null mice, which lack basal cell tight junctions...
Abstract Background The low luminal Ca 2+ concentration of mammalian endolymph in the inner ear is required for normal hearing and balance. We recently reported expression mRNA a -absorptive transport system primary cultures semicircular canal duct (SCCD) epithelium. Results now identify this native vestibular cochlear tissues by qRT-PCR, immunoblots confocal immunolocalization. Transcripts were found quantified several isoforms epithelial calcium channels (TRPV5, TRPV6), buffer proteins...
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Objectives Recent advances in endoscopic technology have allowed its application to middle ear surgery. An antifog agent is necessary for endoscopy because moisture and blood may obscure visibility. Ultrastop one of the most commonly used agents. The current study examined ototoxic effect topical guinea pig ear. Study Design A preliminary experimental animal study. Setting University hospital. Subjects Methods Eighteen male Hartley pigs (weight, 480‐620 g) were divided into 3 groups be...
Abstract Background: Underwater endoscopic ear surgery does not require suction and so protects the inner from unexpected aeration that may damage its function in treatment of labyrinthine fistula. A method underwater is proposed for superior canal dehiscence. Methods: was performed plugging semicircular through transmastoid approach. Saline solution infused into mastoid cavity an Endo-Scrub Lens Cleaning Sheath. The tip inserted endoscope filled completely with saline water. Results: Using...
Objectives/Hypothesis Congenital middle ear anomalies represent a relatively rare condition. This study aimed to describe the characteristics and surgical outcomes for patients with anomalies. Methods A multicenter was conducted of consecutive congenital who underwent primary treatment between January 2008 December 2017. Demographics, procedures, audiometric data were registered into institutional database. Hearing changes postoperative air‐bone gap (ABG) evaluated 1 year after surgery....
Cartilage conduction hearing aids (CC-HAs) are a novel type of aid relying on cartilage conduction, the so-called third auditory pathway. However, CC-HAs have only recently entered routine clinical use, and therefore data their usefulness lacking. The purpose this study was to examine possibility assessing whether individual patients would show good adaptation CC-HAs. Thirty-three subjects (41 ears in total) underwent free trial Age, disease category, pure-tone threshold air bone unaided...
Acute rhinosinusitis is frequently associated with secondary orbital infection, most commonly subperiosteal abscess. Although abscess a deadly disease that might lead to blind and cavernous sinus thrombosis, recent review of literature showed immediate surgical intervention not always be necessary for Orbital inflammation sinusitis common in children, whereas hematoma extremely rare, only 11 reported cases, including one case children. All the cases were treated intervention. Here we present...
The treatment of Gustilo type IIIB and IIIC open fractures remains a challenging problem, because the infection rate is 15-45%. Infection can lead to serious complications such as osteomyelitis or amputation. intra-wound continuous negative pressure irrigation (IW-CONPIT) was developed for infected wounds intractable ulcers, very effective in suppressing accelerating wound healing. Here IW-CONPIT applied severe purpose preventing infection. After thorough debridement lavage wound, bony...
To analyze the outcomes of underwater endoscopic ear surgery (UWEES) technique for closure cholesteatomatous labyrinthine fistula (LF) with preservation auditory function.Retrospective case review study.Tertiary referral center.A total 12 patients LF.Surgical method using UWEES LF to minimize inner damage. Artificial cerebrospinal fluid (CSF) was used as perfusate, except earlier cases when saline employed.Comparison bone conductance hearing level (BCHL) before and after surgery. A change...
To examine the relationship between speech intelligibilities among similar level of hearing loss and threshold elevation auditory brainstem response (ABR).The maximum levels relative click-evoked ABR (ABR - pure tone average at 2,000 4,000 Hz) was retrospectively reviewed in patients with sensorineural (SNHL) other than apparent retrocochlear lesions as neuropathy, vestibular schwannoma brain lesions.Comparison subjects found that variation intelligibility significantly correlated ABR.The...
Objective: To investigate the influence on hearing of transmastoid plugging superior semicircular canal accompanied with membranous transection by underwater endoscopic ear surgery (UWEES) for dehiscence syndrome. Study Design: Retrospective case review. Setting: Tertiary referral center. Patients: Seven patients underwent UWEES from 2017 to 2019. Intervention: Bone conduction (BC) thresholds (250, 500, 1000, 2000, 4000 Hz) were repetitively examined in early postoperative period. Main...
A 43-year-old man with a primary leiomyosarcoma of the left sphenoid sinus is presented. To our knowledge, this an unusual case leiomyosarcoma, which has never been reported in literature. Accurate and safe diagnosis was obtained by endonasal endoscopic approach minimal tissue invasion.
Conclusion. Mitochondrial dysfunction in the cochlea potentiates ototoxicity of aminoglycosides. Objective. This study examined whether mitochondrial affects Materials and methods. Nineteen guinea pigs were treated with toxin 3-nitropropionic acid (3-NP), kanamycin, both agents, or normal saline as control. After 14 days, hair cell loss auditory brainstem response (ABR) assessed. Results. The administration 400 mg/kg kanamycin caused neither nor ABR threshold shift. Administration 3-NP mild...
β-TCP is a biodegradable bone regenerative material which has been noted to possess several limitations due its granular property. Similarly, CM-chitin sponge-like known decompose in the body. Therefore, order improve use of β-TCP, combined form β-TCP/CM-chitin was developed and properties were tested. This study consisted four test groups: The empty control group, hydroxyapatite granule group. These materials implanted mandible canines samples harvested at 2 weeks, 1 month, 3 months after...
Objectives: To describe objective tinnitus complicated with transient low-tone hearing loss coinciding mouth opening, which was related to the connection between mandibular fossa and middle ear space. Patients: A 41-year-old man presented tinnitus, fullness, in left on opening. Main Outcome Measures: Clinical case records, audiological data, radiological analyses including computed tomography (CT) magnetic resonance imaging. Results: Hearing thresholds affected side, were evaluated showed...
Abstract Rigid reconstruction for frontal bone defects not only improves function, but also approximates more normal appearance. However, in cases involving dural scar contractures, a concave deformation remains when rigid is performed without compensating dead space created by swelling of the brain. This study involved 4 which 2-stage procedure was used to first eliminate grafting dermal fat, and subsequently carry out achieve natural forehead configuration. method advantageous considered...