A5101773086- Statistical Methods and Bayesian Inference
- Advanced Causal Inference Techniques
- Statistical Methods and Inference
- Electronic Health Records Systems
- Healthcare Technology and Patient Monitoring
- Medication Adherence and Compliance
- Sepsis Diagnosis and Treatment
- Pharmaceutical Practices and Patient Outcomes
- Psychometric Methodologies and Testing
- Statistical Methods in Clinical Trials
- Survey Sampling and Estimation Techniques
- Quality and Safety in Healthcare
- Coastal wetland ecosystem dynamics
- Gastrointestinal disorders and treatments
- Birth, Development, and Health
- Lymphatic Disorders and Treatments
- Intestinal and Peritoneal Adhesions
- Machine Learning in Healthcare
- Nursing Diagnosis and Documentation
- Qualitative Comparative Analysis Research
- Viral Infections and Immunology Research
- Obesity, Physical Activity, Diet
- Patient Safety and Medication Errors
- Blood Pressure and Hypertension Studies
- Cardiomyopathy and Myosin Studies
Huazhong University of Science and Technology
2025
China Geological Survey
2022
Beijing Tsinghua Chang Gung Hospital
2019
Shandong University
2019
Christiana Care Health System
2013-2018
University of Delaware
2016-2018
Drexel University
2018
Decision Sciences (United States)
2018
Philadelphia University
2018
MedStar Health
2018
Anti-programmed death 1 (αPD1) immune checkpoint blockade is used in combination for cancer treatment but associated with cardiovascular toxicity. Leflunomide (Lef) can suppress the growth of several tumor and mitigate cardiac remodeling mice. However, role Lef αPD1-induced cardiotoxicity remains unclear. Here, we report that inhibits αPD1-related without compromising efficacy αPD1-mediated immunotherapy. changes community structure gut microbiota αPD1-treated melanoma-bearing Moreover, mice...
The nonparametric Mann–Whitney–Wilcoxon (MWW) rank sum test is widely used to treatment effect by comparing the outcome distributions between two groups, especially when there are outliers in data. However, such statistics generally yield invalid conclusions applied nonrandomized studies, particularly those epidemiologic research. Although one may control for selection bias using available approaches of covariates adjustment as matching, regression analysis, propensity score and marginal...
Simpson's paradox is very prevalent in many areas. It characterizes the inconsistency between conditional and marginal interpretations of data. In this paper, we illustrate through some examples how can happen continuous, categorical, time-to-event data.辛普森悖论普遍存在于很多领域。它具有数据 的条件性和边缘性解释之间的不一致特征。在本文中， 我们通过一些例子来阐述辛普森悖论是如何在连续性、 分类和时间- 事件数据中产生的。.
Poisson log-linear regression is a popular model for count responses. We examine two extensions of this – the generalized estimating equations (GEE) and linear mixed-effects (GLMM) to longitudinal data analysis complement existing literature on characterizing relationship between dueling paradigms in setting. Unlike regression, GEE GLMM carry significant conceptual practical implications when applied modeling data. Our findings shed additional light differences classes models used...
Chylous ascites is the pathologic leakage of triglycerides-rich lymphatic fluid into peritoneal cavity. a rare complication in abdominal surgery. This study aimed to find relatively better method for nutrition support treatment chylous after surgery.This was retrospective study. retrospectively reviewed patients who underwent surgery and developed ascites, from year 2010 2014, at West China Hospital Sichuan University Affiliated Zunyi Medical College. Fifty-eight were included The clinical...
Hypertensive disorders of pregnancy ( HDP ) are associated with cardiovascular disease CVD later in life. The authors investigated the association blood pressure BP and arterial stiffness 1‐year postpartum. Seventy‐four participants, 33 an 41 uncomplicated pregnancies, were examined using applanation tonometry to measure , carotid‐femoral pulse wave velocity (cf PWV ), augmentation index AI x). On average, women had a 9 mm higher systolic P <.01), 0.8 m/s faster cf =.09), 5.4% greater x...
Many approaches, including traditional parametric modeling and machine learning techniques, have been proposed to estimate propensity scores. This paper describes a new model averaging approach score estimation in which nonparametric estimates are combined achieve covariate balance. Simulation studies conducted across different scenarios varying the degree of interactions nonlinearities treatment model. The results show that, based on inverse probability weighting, estimator produces less...
Zero-inflated count outcomes arise quite often in research and practice. Parametric models such as the zero-inflated Poisson negative binomial are widely used to model responses. Like most parametric models, they sensitive departures from assumed distributions. Recently, new approaches have been proposed provide distribution-free, or semi-parametric, alternatives. These methods extend generalized estimating equations robust inference for population mixtures defined by outcomes. In this...
As health-care organizations transition from paper to electronic documentation systems, capturing the nursing assessment electronically can play a fundamental role in transforming delivery. Especially preventive health, capture of assessment, combined with vital sign-based monitoring, support early detection physiological deterioration patients. While Early Warning Systems have potential detect signals deterioration, their clinical interpretation and integration into workflow hospital-based...
With the recognition that introduction of new technology causes changes in workflow and may introduce errors to system, usability testing was performed provide data on nursing practice interaction with infusion pump technology. Usability provides opportunity detect analyze potentially dangerous problems design pumps could cause or allow avoidable errors. This work will reduce preventable harm through optimization health care delivery.
Survival analysis concerns the time from a well-defined origin to some event of interest, such as surgery death cancer patient, wedding divorce, and between first second suicide attempts. Although originated in research on active lifetime light bulbs other electric devices, modern applications survival include many non-survival events. Thus, may be more appropriately called time-to-event analysis. Like all statistical methods, deals with random events death, divorce suicide. interest is...
AbstractOutliers are commonly observed in psychosocial research, generally resulting biased estimates when comparing group differences using popular mean-based models such as the analysis of variance model. Rank-based methods Mann–Whitney–Wilcoxon (MWW) rank sum test more effective to address outliers. However, available for inference limited cross-sectional data and cannot be applied longitudinal studies under missing data. In this paper, we propose a generalized MWW multiple groups with...
Estimating causal treatment effect for randomized controlled trials under post‐treatment confounding, that is, noncompliance and informative dropouts, is becoming an important problem in intervention/prevention studies when the exposures are not completely controlled. When confounding present a study, traditional intention‐to‐treat approach could underestimate because of insufficient exposure treatment. In recent two decades, many papers have been published to address such confounders...
Intraclass correlation coefficients (ICC) are employed in a wide range of behavioral, biomedical, psychosocial, and health care related research for assessing reliability continuous outcomes. The linear mixed-effects model (LMM) is the most popular approach inference about ICC. However, since LMM normal distribution-based non-normal data norm rather than exception studies, its applications to real study always beg question validity. In this paper, we propose distribution-free alternative...
An information technology solution to provide a real-time alert the nursing staff is necessary assist in identifying patients who may have sepsis and avoid devastating effects of its late recognition. The objective this study evaluate perception adoption clinical decision support.A cross-sectional survey over three-week period 2015 was conducted major tertiary care facility. A launched into five pilot units (including: surgery, medical-ICU, step-down, general medicine, oncology). unit...
Hemophilic pseudotumor is a rare but well-known complication of hemophilia manifesting as recurrent hemorrhage and progressive enlargement hematoma. A patient with severe has 1% to 2% chance develop pseudotumor. The chronic pressure osseous usually results in bone destruction or resorption. Cranial hemophilic pseudotumors are extremely rare, only 7 reported cases associated mild moderate factor VIII IX deficiency. 42-year-old man deficiency developed the bilateral skull. Computed tomography...