- Education, sociology, and vocational training
- Bacterial Infections and Vaccines
- Healthcare Systems and Practices
- Influenza Virus Research Studies
- Agriculture and Rural Development Research
- French Urban and Social Studies
- Legionella and Acanthamoeba research
- French Language Learning Methods
- Toxoplasma gondii Research Studies
- Pneumonia and Respiratory Infections
- Mosquito-borne diseases and control
- Parasitic Infections and Diagnostics
- Health, Medicine and Society
- COVID-19 epidemiological studies
- Respiratory viral infections research
- Viral Infections and Outbreaks Research
- Food Safety and Hygiene
- Vibrio bacteria research studies
- Linguistics and Discourse Analysis
- Data-Driven Disease Surveillance
- Tuberculosis Research and Epidemiology
- Viral Infections and Vectors
- Clostridium difficile and Clostridium perfringens research
- Travel-related health issues
- Salmonella and Campylobacter epidemiology
Santé Publique France
1994-2024
Université de Lille
2022-2024
Institut thématique Santé Publique
2019-2024
Université de Caen Normandie
2020-2023
Centre Interdisciplinaire de Recherche Normand en Education et Formation
2017-2023
Centre Nantais de Sociologie
2010-2018
Centre de Recherche en Éducation de Nantes
2010-2018
Centre Hospitalier Universitaire de Liège
2004-2017
Institut de Veille Sanitaire
1997-2016
Nantes Université
2016
To determine the incidence rate of complications associated with vascular catheters in intensive care unit patients and to analyze risk factors for a positive culture, we performed multicenter study at eight French hospitals. During period, 865 intravenous were inserted 566 patients; 362 (41.8%) peripheral catheters, 503 (58.2%) central catheters. Local (i.e., infiltration) occurred significantly more often than (P less 0.001); contrast, fever bacteremia 0.01 P 0.05, respectively). The...
An increase in the incidence and severity of Clostridium difficile-associated disease Québec United States has been associated with a hypervirulent strain referred to as North American pulsed-field type 1 (NAP1)/027.In 2005, prospective study was conducted 88 hospitals, 478 consecutive nosocomial isolates C. difficile were obtained. The subjected gel electrophoresis (PFGE) typing, antimicrobial susceptibility testing, detection binary toxin genes tcdC gene deletion. Data on patient age...
The current Zika virus outbreak and its potential severe health consequences, especially congenital fetal syndrome, have led to increased concern about sexual transmission, in pregnant women of reproductive age. Here we report a case likely male-to-female, totally asymptomatic couple.
As a result of their intimate contact with the land and nutritional habits, Inuit Nunavik are considered to be at risk from zoonotic infections. To better understand factors for Toxoplasma gondii infection, serosurvey was conducted in Nunavik, Québec, September 2004. A representative sample adult population participated this cross-sectional study (n = 917). Antibodies (IgG) against T. were detected by immunoassay. Information on sociodemographic characteristics, traditional activities,...
The temporal and spatial association of meningococcal disease influenza-like syndrome (ILS) was assessed from surveillance data on these diseases in France for a 6-year period (1985-1990). Using time series methods to account the usual seasonal pattern disease, incidence given week found be linked ILS 5 previous weeks but not that subsequent weeks. Geographic spread correlated with ILS. This study also suggests is more severe 2-month during after an epidemic: proportion cases purpura...
We conducted a study to determine the incidence of haemolytic uraemic syndrome (HUS) in children France and assess role Shiga-toxin-producing Escherichia coli (STEC) infection aetiology HUS. In collaboration with Société de Néphrologie Pédiatrique we undertook retrospective review all cases HUS hospitalized from January 1993 March 1995 1-year prospective (April 1995-March 1996) epidemiological microbiological features The polymerase chain reaction (PCR) procedure was used detect stx, eae,...
During the 2009/10 pandemic, a national surveillance system for severe influenza cases was set up in France. We present results from system's first four years. All admitted to intensive care units (ICU) were reported Institut de Veille Sanitaire using standardised form: data on demographics, immunisation and virological status, risk factors, severity (e.g. acute respiratory distress syndrome (ARDS) onset, mechanical ventilation, extracorporeal life support) outcome. Multivariate analysis...
Abstract Background Estimating the global burden of influenza hospitalizations is required to allocate resources and assess interventions that aim prevent severe influenza. In France, current routine surveillance system does not fully measure cases. The objective was describe characteristics severity by age‐group season between 2012 2017. Methods All with a diagnosis in metropolitan France July June 2017 were extracted from French national hospital discharge database (PMSI). For each season,...
Experimental studies indicated that long-chain polyunsaturated fatty acids may increase sensitivity of mammary tumours to several cytotoxic drugs. To evaluate this hypothesis in breast cancer, we have prospectively studied the association between levels stored adipose tissue and response tumour chemotherapy 56 patients with an initially localized carcinoma. Adipose was obtained at time biopsy, individual were measured as a percentage total using capillary gas chromatography. Patients then...
To explore epidemiological patterns of the incidence Clostridium difficile infection (CDI) and hospital characteristics associated with increased during nonepidemic epidemic years.Retrospective prospective ecological study.Eighty-three acute care hospitals participating in CDI surveillance province Quebec, Canada.A Serfling-type regression model applied to data obtained from an administrative database (1998-2006) Quebec (2004-2006) was used calculate expected baseline detect exceeding...
The presence of norovirus in shellfish is a public health concern Europe. Here, we report the results an investigation into gastroenteritis outbreak following festive lunch which affected 84 (57%) residents and staff members nursing home January 2012 France. Individuals who had eaten oysters significantly higher risk developing symptoms 2·5 days than those not, increasing with amount [relative 2·2 (1·0-4·6) 3·3 (1·6-6·6) for 3-4 5-12 oysters, respectively]. In healthy individuals during...
Abstract We describe severe acute respiratory syndrome (SARS) in France. Patients meeting the World Health Organization definition of a suspected case underwent clinical, radiologic, and biologic assessment at closest university-affiliated infectious disease ward. Suspected cases were immediately reported to Institut de Veille Sanitaire. Probable case-patients isolated, their contacts quarantined home, followed for 10 days after exposure. Five probable occurred from March through April 2003;...
The purpose of this study was to report the temporal trends incidence ciguatera poisoning from 1992 2001 in French Polynesia.This retrospective analysed 7842 cases disease recorded over a period 10 years.The annual varied 26.3 41.9 per 10,000 person-years. An analysis grouped by archipelago revealed differences incidences (P < 0.0001) with most remote archipelagos having highest incidences. A detailed on sub-sample for which clinical information available (n = 1824) confirmed neurological...
In December 2008, three hospitalized cases of suspected psittacosis infection were notified by respiratory disease clinicians from a local hospital to the Regional Epidemiology Unit Pays de la Loire, France. They all had attended bird fair. A retrospective cohort study was conducted among exhibitors and organizers identify potential risk factors in relation this Environmental veterinary investigations implemented trace sources infection. We identified two confirmed, probable 44 possible...
To date, estimating the burden of seasonal influenza on hospital system in France has been restricted to diagnoses patients (estimated hospitalization rate 35/100,000 average from 2012 2018). However, many hospitalizations for diagnosed respiratory infections (e.g. pneumonia, acute bronchitis) occur without concurrent screening virological influenza, especially elderly. Specifically, we aimed estimate French by examining proportion severe (SARI) attributable influenza.Using national...
Abstract Background Morbidity, severity, and mortality associated with annual influenza epidemics are of public health concern. We analyzed surveillance data on hospitalized laboratory-confirmed cases admitted to intensive care units identify common determinants for fatal outcome inform target prevention strategies, including risk communication. Methods performed a descriptive analysis used Poisson regression models robust variance estimate the association age, sex, virus (sub)type,...
An epidemic of dengue 1 virus (DENV-1) occurred in French Polynesia 2001, 4 years after a DENV-2 that ended 1997. Surveillance data from hospitalized case-patients showed with hemorrhagic fever (DHF) exhibited bimodal age distribution peak among infants 6-10 months and second at 4-11 age. The relative risk DHF developing children born before rather than the was 186 (95% confidence interval 26-1,324). Among toward end epidemic, strong temporal association found between month birth being for...
Few infections can cause the social stress that occurs when meningococcal disease enters a community. The ability of Neisseria meningitidisto kill healthy child within few hours is one reason for this fear. It also clear preventive measures ag