A5058093786- Genetics, Aging, and Longevity in Model Organisms
- Food composition and properties
- Microbial Metabolites in Food Biotechnology
- Gut microbiota and health
- Natural Antidiabetic Agents Studies
- Diet and metabolism studies
- Sirtuins and Resveratrol in Medicine
- Enzyme Production and Characterization
- Polysaccharides and Plant Cell Walls
- Circadian rhythm and melatonin
- Proteins in Food Systems
- Pancreatic function and diabetes
- Liver Disease Diagnosis and Treatment
- Dietary Effects on Health
- Probiotics and Fermented Foods
- Phytase and its Applications
- Polysaccharides Composition and Applications
- Fungal Biology and Applications
- Coenzyme Q10 studies and effects
- Autophagy in Disease and Therapy
- Advances in Cucurbitaceae Research
- Plant Pathogens and Fungal Diseases
- Traditional Chinese Medicine Analysis
- Adipokines, Inflammation, and Metabolic Diseases
- Selenium in Biological Systems
Jiangsu University
2016-2025
Ningxia Medical University
2024
Wenzhou Medical University
2022-2024
Jiangnan Industry Group (China)
2021-2022
Jilin Agricultural University
2021
Purdue University West Lafayette
2020
Shanxi Medical University
2018
Sichuan University
2017
Abstract BACKGROUND Barley contains a relatively high concentration of the mixed‐linkage (1 → 3) 4) β ‐glucan, which has been reported to be functional food with prebiotic potential. In current study we compared properties two neutral barley ‐glucans, obtained from raw barley: ‐glucan (RBG) and Lactobacillus plantarum dy‐1‐fermented (FBG). RESULTS Molecular characteristics revealed that molecular weight decreased 1.13 × 10 5 D 6.35 4 after fermentation. Fermentation also improved water / oil...
This article explored the effect of Lactobacillus plantarum dy-1 (L. dy-1) fermentation on basic physicochemical properties and associated in vitro antioxidant activity barley β-glucan, including its molecular weight, monosaccharide composition, characteristic structure rheology. Its DPPH, ABTS, hydroxyl radical scavenging capacity, ferric reducing potential (FRAP) were measured at different times. The results showed that weight β-glucan was decreased from 1.052 × 105 Da to 4.965 104 within...
Abstract Red rice is a kind of whole grain with health benefits. Probiotic fermentation widely applied to promote nutrient release from cereals and improve bioactivity. The study aims investigate the impact Lactiplantibacillus plantarum ( L. ) dy‐1 on bioactivities, bioaccessibility, lipid‐lowering activities red rice. Results indicated that significantly increased protein total phenolic content by 1.7 1.4 times rice, as well essential nonessential amino acids. Fermentation remarkably...
Abstract Latic acid fermentation is an effective way to release the bound phenolic acids from grains dietary fiber improve biological effects in vivo. Previous analysis of whole genome sequencing and comparative proteomics has revealed that a sulfatase named LPMS Lactiplantibacillus plantarum dy‐1 ( L. dy‐1) was potential key enzyme promoting phenol barley bran fiber. In this present study, we utilized gene editing technology modify verify role releasing bond during fermentation. Results...
Lactobacillus plantarum fermented barley extract (LFBE) has a potent anti-obesity effect on high-fat-diet fed (HFD) obese rats. However, the underlying mechanism remains unclear. Herein, we investigated and of LFBE in 3 T3-L1 preadipocytes HFD-induced significantly inhibited lipid accumulation by decreasing expression adipogenesis-related transcription factors, including peroxisome proliferator-activated receptor (PPAR-γ) CCAAT/enhancer binding protein (C/EBP-α) differentiated cells. The...
In this study, the different characteristics of in vitro digestion and fermentation were investigated compared with polysaccharides extracted by hot water alkali sequence from Volvariella volvacea (VWEP VAEP, respectively), as well vivo lipid-reducing effects. The results indicated that simulated saliva-gastrointestinal altered reducing sugar contents, molecular weights (from 7.398 × 104 D to 3.080 103 D, 4.110 6.080 D), chemical components, antioxidant activities VWEP respectively. However,...
Barley, rich in bioactive components including dietary fiber, polyphenolic compounds and functional proteins, exhibits health benefits such as regulating glucose lipid metabolism. Previous studies have found that the content composition of free phenolic acids barley may be significantly changed by fermentation with laboratory patented strain Lactobacillus plantarum dy-1 (L. p dy-1), but mechanism enzymatic release acid remains to elucidated. Based on this, this study aimed identify key...
The effects on gut microbiota of type 2 diabetic rats fed a bitter melon formulation (BLSP, lyophilized superfine powder) were investigated. BLSP treatment significantly reduced fasting blood glucose levels (p < 0.05) and serum insulin the rats. treated control profiled by PCR amplification pyrosequencing 16S rRNA genes (V3-V9 region). ratio Firmicutes to Bacteroidetes in rats, while relative abundances Ruminococcaceae, Bacteroides Ruminococcus lowered BLSP-treated compared Additionally,...
Abstract Overly active acyl‐coenzyme A: cholesterol acyltransferases (ACATs) are known to contribute the development of atherosclerosis, cancer cell proliferation and de novo lipogenesis. However, role ACAT in systemic lipid metabolism its consequence aging is unknown. Using avasimibe, a clinically proven inhibitor, mboa‐1 mutant strain, homologous mammalian , herein, we found that Ava treatment exhibited decreased fat accumulation during feeding increased lipolysis with extended lifespan C....
Barley bran has potential bioactivities due to its high content of polyphenols and dietary fiber, etc. Fermentation been considered as an effective way promote the functional activity food raw materials. In this study, polysaccharides from barley extract fermented by Lactiplantibacillus plantarum dy-1 (FBBE-PS) were analyzed, effects on lipid accumulation oxidative stress in high-fat HepG2 cells induced sodium oleate evaluated. The results showed that molecular weight decreased...
Carbendazim, as a fungicide, was commonly used to control fungal diseases in agriculture, forestry, and veterinary medicines. In this study, the acute reproductive toxicity of carbendazim assessed using Caenorhabditis elegans ( C. ) model order preliminarily evaluate potential risks fungicide agricultural production application. The results showed that growth inhibited by 0.01 μ g/L carbendazim. treatment 0.1 caused significant decrease locomotion behavior damage antioxidant system, causing...
Bitter melon is widely applied to the treatment of diabetes and obesity, but few studies focus on processing procedure bitter melon. The differences in physical properties, bioaccessibility, anti-obesity activity powder (BMP) produced with or without superfine grinding were investigated optimize an effective procedure.Results showed that could improve properties BMP, represented by greater bulk density, lower water-holding capacity, higher bioactive compounds' solubilities. Superfine...