Mario Giorgi

ORCID: 0000-0003-3657-4703
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About
Contact & Profiles
Research Areas
  • Veterinary Pharmacology and Anesthesia
  • Antibiotics Pharmacokinetics and Efficacy
  • Pharmacological Effects and Assays
  • Inflammatory mediators and NSAID effects
  • Veterinary Equine Medical Research
  • Animal Nutrition and Physiology
  • Analytical Methods in Pharmaceuticals
  • Veterinary medicine and infectious diseases
  • Coccidia and coccidiosis research
  • Pesticide Residue Analysis and Safety
  • Meat and Animal Product Quality
  • Mycotoxins in Agriculture and Food
  • Pharmacogenetics and Drug Metabolism
  • Antibiotic Resistance in Bacteria
  • Animal Behavior and Welfare Studies
  • Turtle Biology and Conservation
  • Helminth infection and control
  • Anesthesia and Pain Management
  • Drug-Induced Hepatotoxicity and Protection
  • Neuropeptides and Animal Physiology
  • Bacterial Identification and Susceptibility Testing
  • Effects of Environmental Stressors on Livestock
  • Insect and Pesticide Research
  • Animal testing and alternatives
  • Anesthesia and Sedative Agents

University of Pisa
2016-2025

Kanchanaburi Rajabhat University
2025

Universidad de Murcia
2025

University of Sassari
2018-2024

National Veterinary Research Institute
2024

The University of Queensland
2017-2023

Washington State University
2023

American College of Veterinary Surgeons
2023

North Carolina State University
2023

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2019-2022

Boron nitride nanotubes (BNNTs) have attracted huge attention in many different research fields thanks to their outstanding chemical and physical properties. During recent years, our group has pioneered the use of BNNTs for biomedical applications, first all assessing vitro cytocompatibility on cell lines. At this point, vivo investigations are necessary before proceeding toward realistic developments proposed applications. In communication, we report a pilot toxicological study rabbits....

10.2147/ijn.s28144 article EN cc-by-nc International Journal of Nanomedicine 2012-01-01

Glioblastoma multiforme is one of the deadliest forms cancer, and current treatments are limited to palliative cares. The present study proposes a nanotechnology-based solution able improve both drug efficacy its delivery efficiency.Nutlin-3a superparamagnetic nanoparticles were encapsulated in solid lipid nanoparticles, obtained nanovectors (nutlin-loaded magnetic nanoparticle [Nut-Mag-SLNs]) characterized by analyzing their physicochemical properties effects on U-87 MG glioblastoma...

10.2217/nnm-2018-0436 article EN cc-by-nc-nd Nanomedicine 2018-12-21

Abstract The present study aimed at investigating the impact of heat challenges on gut microbiota composition in growing pigs and its relationship with pigs’ performance thermoregulation responses. From a total 10 F1 sire families, 558 564 backcross Large White × Créole were raised phenotyped from 11 to 23 wk age temperate (TEMP) tropical (TROP) climates, respectively. In TEMP, all subjected an acute challenge (3 29 °C) 26 age. Feces samples collected both TEMP TROP climate (TEMP23 TROP23...

10.1093/jas/skz222 article EN cc-by-nc-nd Journal of Animal Science 2019-07-02

The present study was undertaken to characterize the plasma kinetic disposition of tolfenamic acid (TA) in freshwater crocodiles. In total, 15 crocodiles were used experiment and randomly divided into three groups, with TA administered at 2 mg/kg body weight (b.w.) intravenously (IV) or 4 b.w. intramuscularly (IM). Blood samples collected predetermined times up 168 h after IV IM drug administration. Plasma concentrations determined using validated high-performance liquid chromatography a UV...

10.3390/ani15050684 article EN cc-by Animals 2025-02-26

In reptiles, administration of opioid drugs has yielded unexpected results with respect to analgesia. The aims this study were assess the pharmacokinetic/pharmacodynamic (PK/PD) properties tramadol and its active metabolite M1 evaluate effect renal portal system on PK/PD parameters in yellow-bellied slider turtles. Turtles (n = 19) randomly assigned four treatment groups, according a masked, single-dose, four-treatment, unpaired, four-period crossover design. Group A 5) received single i.m....

10.1111/jvp.12206 article EN Journal of Veterinary Pharmacology and Therapeutics 2015-01-27

The objective of this study was to estimate the genetic parameters for thermoregulation traits and relationships with performance Large White lactating sows reared in a tropical humid climate. were rectal temperature (RT), cutaneous (CT) respiratory rate (RR) during lactation measured afternoon (1200 h) morning (0700 h). production sow's average daily feed intake (ADFI), litter BW gain (LBWg) proportion change between farrowing weaning (BWc). Complete data included 931 on 329 from INRA...

10.1017/s175173111600135x article EN cc-by-nc-nd animal 2016-07-05

The purpose of this study was to assess the pharmacokinetics robenacoxib (RX), a COX-2 selective non-steroidal anti-inflammatory drug, in goats after single intravenous (IV), subcutaneous (SC) and oral (PO) administrations. 5-month-old healthy female (n = 8) were used. animals subjected three-phase, two-dose (2 mg/kg IV, 4 SC, PO) unblinded, parallel design, with four-month washout period between IV SC treatment, one-week PO treatment. Blood drawn from jugular vein heparinized vacutainer...

10.1111/jvp.13396 article EN cc-by-nc Journal of Veterinary Pharmacology and Therapeutics 2023-05-28

Abstract AIM: To compare the rectal and I/V administration of tramadol in dogs, to assess both its pharmacokinetic properties absolute bioavailability. METHODS: After via suppositories injection (4 mg/kg), concentration main metabolites, O-desmethyl-tramadol (M1), N-desmethyl-tramadol (M2) N,O-didesmethyl-tramadol (M5), were determined plasma, using high-performance liquid chromatography (HPLC). A balanced cross-over study was used, involving six male Beagle dogs. RESULTS: Plasma...

10.1080/00480169.2009.36894 article EN New Zealand Veterinary Journal 2009-06-01

The prevalence of mycotoxins is often increased by the climatic conditions prevailing in tropical regions. Reports have revealed contamination some types vegetable oil. However, oil one essential ingredients used food preparation. Thus, this study determined occurrence multi-mycotoxins six oils commercially available Thailand to assess consumer health risk. In total, 300 samples (olive oil, palm soybean corn sunflower and rice bran oil) collected from various markets were analyzed for...

10.3390/foods10112795 article EN cc-by Foods 2021-11-13
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