Xiaokun Hu

ORCID: 0000-0003-3695-4319
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About
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Research Areas
  • Glioma Diagnosis and Treatment
  • Medical Imaging Techniques and Applications
  • Radiomics and Machine Learning in Medical Imaging
  • Advanced Radiotherapy Techniques
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Medical Image Segmentation Techniques
  • Manufacturing Process and Optimization
  • MRI in cancer diagnosis
  • Radiopharmaceutical Chemistry and Applications
  • Brain Metastases and Treatment
  • Microbial Inactivation Methods
  • Advanced Numerical Analysis Techniques
  • Nanoplatforms for cancer theranostics
  • Lung Cancer Treatments and Mutations
  • Calcium signaling and nucleotide metabolism
  • Advanced MRI Techniques and Applications
  • Cancer Immunotherapy and Biomarkers
  • Bone fractures and treatments
  • Helicobacter pylori-related gastroenterology studies
  • Lung Cancer Diagnosis and Treatment
  • Digital Radiography and Breast Imaging
  • Renal cell carcinoma treatment
  • Cardiovascular Disease and Adiposity
  • Bone Tissue Engineering Materials
  • Advanced Measurement and Metrology Techniques

Xi'an Jiaotong University
2023-2025

Hunan Children's Hospital
2023-2024

Central South University
2024

Affiliated Hospital of Qingdao University
2017-2024

Qingdao University
2017-2024

Ningxia Medical University
2024

Chinese Research Academy of Environmental Sciences
2023

University of South China
2023

Wannan Medical College
2022

The First Affiliated Hospital, Sun Yat-sen University
2022

Disulfidptosis refers to a specific programmed cell death process characterized by the accumulation of disulfides. It has recently been reported in several cancers. However, impact disulfidptosis-related long non-coding RNAs (lncRNAs) on malignant tumors remained largely unknown. In present work, we screened prognostic lncRNAs and studied their effects lung adenocarcinoma. Relevant clinical data adenocarcinoma cases were retrieved from The Cancer Genome Atlas (TCGA) database. RNA sequencing...

10.1016/j.ncrna.2024.03.006 article EN cc-by-nc-nd Non-coding RNA Research 2024-03-21

Abstract: Typical physiological characteristics of tumors, such as weak acidity, low oxygen content, and upregulation certain enzymes in the tumor microenvironment (TME), provide survival advantages when exposed to targeted attacks by drugs responsive nanomedicines. Consequently, cancer treatment has significantly progressed recent years. However, evolution adaptation still pose many challenges for current methods. Therefore, efficient precise treatments require an understanding...

10.2147/ijn.s453265 article EN cc-by-nc International Journal of Nanomedicine 2024-05-01

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10.2139/ssrn.5085087 preprint EN 2025-01-01

Due to manufacturing and assembly errors, the accuracy of spacecraft cabin is inevitably affected. To minimize these errors improve operational performance, we apply a comprehensive analysis method that accounts for non-ideal surfaces. First, 3D model cabin’s surfaces developed using skin shapes small displacement torsor theory represent form positional respectively. However, previous studies have often overlooked impact errors. Next, an improved deviation propagation introduced analyze...

10.1177/09544054251333962 article EN Proceedings of the Institution of Mechanical Engineers Part B Journal of Engineering Manufacture 2025-05-08

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Liu S, Wang H, C, et al. Dosimetry verification of 3D-printed individual template based on CT-MRI fusion for radioactive 125I seed implantation in recurrent high-grade gliomas. Journal Contemporary Brachytherapy. 2019;11(3):235-242. doi:10.5114/jcb.2019.85729. APA Liu, S., Wang, H., C., Zhang, Li, W., & Dong, Q. (2019). Brachytherapy, 11(3), 235-242. https://doi.org/10.5114/jcb.2019.85729 Chicago Shifeng, Hong...

10.5114/jcb.2019.85729 article EN cc-by-nc-sa Journal of Contemporary Brachytherapy 2019-01-01

Abstract The rotation accuracy of a machine tool spindle is essential for ensuring the machining precision. Due to existence manufacturing and assembly errors, will be inevitably impacted degraded. Therefore, reduce influence errors improve work performance, this paper focuses on analysis novel optimization-oriented skin model shape method tackle highly complex problem. First, structural carried out elaborate intractable full parallel collections in assembly. Then, based iterative closest...

10.1093/jcde/qwad086 article EN cc-by-nc Journal of Computational Design and Engineering 2023-09-01

Background: Primary brain tumors have always been associated with high morbidity and mortality. Glioma is the most common type of malignant tumors,with a probability recurrence after surgical excision poor prognosis.The purpose this study was to compare therapeutic efficacy computed tomography (CT)-guided interstitial 125I seed implantation traditional radiochemotherapy for treatment recurrent gliomas. Results: The response rate at 1, 3, 6 12 months 68.6, 74.3, 77.1 62.8% respectively, which...

10.4161/cbt.20834 article EN Cancer Biology & Therapy 2012-08-01

Background: Ischemic stroke treatment is a challenge worldwide. The efficacy and safety of mesenchymal stem cells (MSCs) for have been confirmed. However, poor survival MSCs in the ischemic environment limits therapy efficacy. Changes MSC status after transplantation difficult to monitor. This study aimed deliver brain-derived neurotrophic factor (BDNF)-overexpressing by hydrogel (H-B-MSCs) promote recovery stroke. Methods: were transfected with lentivirus carrying luc2 BDNF cassette....

10.21037/atm-22-5921 article EN Annals of Translational Medicine 2022-12-01

Abstract Background The prognosis of patients with progressive or recurrent high-grade gliomas (HGGs) after surgery remains poor. Iodine-125 brachytherapy is emerging as a salvage method for the treatment gliomas. This study aimed to investigate whether permanent iodine-125 could be used an effective therapeutic even without radiotherapy and/or chemotherapy HGG gross total resection. Methods Between March 2004 and August 2016, 58 resection were included in this study. Twenty-nine underwent...

10.1186/s12885-020-07086-8 article EN cc-by BMC Cancer 2020-06-24

Abstract Objective The purpose of this study was to develop a combined radiomics model predict coronary plaque texture using perivascular fat CT features with clinical risk factors. Methods data 200 patients plaques were retrospectively analyzed and randomly divided into training group validation at ratio 7:3. In the group, best feature set selected by maximum correlation minimum redundancy method least absolute shrinkage selection operator. Radiomics models built based on different machine...

10.1186/s12880-022-00858-7 article EN cc-by BMC Medical Imaging 2022-07-29

Irreversible electroporation (IRE) is a soft tissue ablation technique that uses short electrical fields which induce the death of target cells. To evaluate safety and efficacy an IRE-based device compared to regular radiofrequency (RFA) solid liver tumors, in this multicenter, randomized, parallel-arm, non-inferiority study, 152 patients with malignant tumors were randomized into IRE (n = 78) RFA 74) groups. The primary endpoint was success rate tumor ablation; secondary endpoints included...

10.3389/fonc.2022.945123 article EN cc-by Frontiers in Oncology 2022-09-29
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