A5043859119- Reproductive Biology and Fertility
- Ovarian function and disorders
- Assisted Reproductive Technology and Twin Pregnancy
- Prenatal Screening and Diagnostics
- Gynecological conditions and treatments
- Reproductive System and Pregnancy
- Endometriosis Research and Treatment
- Reproductive Health and Technologies
- CO2 Reduction Techniques and Catalysts
- Renal and related cancers
- Ectopic Pregnancy Diagnosis and Management
- Polyoxometalates: Synthesis and Applications
- Chromosomal and Genetic Variations
- Genomic variations and chromosomal abnormalities
- Sperm and Testicular Function
- Carbon dioxide utilization in catalysis
- Uterine Myomas and Treatments
- Pluripotent Stem Cells Research
- Reproductive Health and Contraception
- Catalytic Cross-Coupling Reactions
- Phytoestrogen effects and research
- Advanced Glycation End Products research
- Click Chemistry and Applications
- Nanocluster Synthesis and Applications
- Catalytic C–H Functionalization Methods
First Affiliated Hospital of Zhengzhou University
2016-2025
Robert Bosch (Germany)
2019-2024
Second Affiliated Hospital of Fujian Medical University
2023-2024
Fujian Medical University
2023-2024
Institute of Catalysis and Petrochemistry
2024
Harbin Engineering University
2023-2024
National Institute for Parasitic Diseases
2022-2024
East China University of Science and Technology
2022-2023
Shaanxi Provincial Hospital of Traditional Chinese Medicine
2022
Henan University
2020-2021
Background: The sperm DNA fragmentation index (DFI) is widely regarded as a key measure for assessing male fertility, but the predictive value of DFI outcomes assisted reproductive technology (ART) remains under debate. In this study, we used large sample to analyze effect on pregnancy following ART and its relationship with oocyte fertilization embryo development in vitro (IVF)/intracytoplasmic injection (ICSI). We also explore (SDF) associated factors fertility. Methods: between measured...
In order to explore the relationship between serum progesterone (P) level on day of human chorionic gonadotrophin (HCG) administration and cumulative live birth rate in patients with different ovarian response during vitro fertilization (IVF), we carried out this retrospective cohort study including a total 4,651 undergoing their first IVF cycles from January 2011 December 2012. All final outcome (4,332 patients) were divided into three groups according response: poor responder (≤5 oocytes,...
Background Some VOCs are identified as endocrine-disrupting chemicals (EDCs), interfering with the effect of sex hormones. However, no studies focused on common spectrum environmental exposure affecting hormones in average male population. Objectives We aimed to explore association between and American adult males using multiple statistical models. Methods The generalized linear (GLM), eXtreme Gradient Boosting (XGBoost), weighted quantile sum (WQS), Bayesian kernel machine regression (BKMR)...
In this paper, the effect of basalt fiber (BF) on frost resistance concrete under different curing conditions was investigated, and its mechanism analyzed. Three (normal curing, short-term seawater curing) were adopted, with BF volume contents designed. Freeze-thaw (FT) tests carried out using rapid freezing method to test reinforced (BFRC). Additionally, mass loss rate (MLR), relative dynamic modulus elasticity (RDME) change, compressive strength reduction specimens during freeze-thaw...
Reciprocal translocations (RecT) and Robertsonian (RobT) are among the most common chromosomal abnormalities that cause infertility birth defects. Preimplantation genetic testing for aneuploidy using comprehensive chromosome screening in vitro fertilization enables embryo selection with balanced ploidy; however, it is normally unable to determine whether an a translocation carrier. Here we report method named "Mapping Allele Resolved Carrier Status" (MaReCs), which ploidy resolution of...
Background: Female overweight/obesity has been reported to be associated with compromised pregnancy outcomes in fresh embryo transfer cycles. It is unclear whether the cumulative live birth rate (CLBR) adversely affected after all viable embryos are transferred from first ovarian stimulation cycle. Objectives: To investigate CLBR was obese women. Method: A total of 9,772 young women underwent their IVF/ICSI cycles January 2012 October 2017. Pregnancy were compared according female BMI....
Abstract Background This study aimed to evaluate the cut-off value of anti-Müllerian hormone (AMH) combined with body mass index (BMI) in diagnosis polycystic ovary syndrome (PCOS) and morphology (PCOM). Methods retrospective included 15,970 patients: 3775 women PCOS, 2879 PCOM, 9316 patients as controls. Multivariate logistic regression analysis was used calculate adjusted odds ratios (ORs) 95% confidence intervals (CIs) for AMH. We randomly divided into two data sets. In dataset 1, a...
Metabolic Syndrome (MS) is a cluster of conditions that significantly increase the risk infertility in women. Granulosa cells are crucial for ovarian folliculogenesis and fertility. Understanding molecular alterations these can provide insights into MS-associated infertility. This study aimed to investigate Differentially Expressed Genes (DEGs) Proteins (DEPs) granulosa from female patients with Transcriptome proteome analyses were integrated compare three MS control subjects. RNA sequencing...
Abstract Abnormality of granulosa cells (GCs) is the critical cause follicular atresia in premature ovarian failure (POF). RIPK3 highly expressed GCs derived from atretic follicles. We focus on uncovering how contributes to GC senescence. Primary were treated with H₂O₂ induce ROS was detected via DCFH‐DA staining. Levels senescence‐related molecules and SA‐β‐Gal activity examined. Cyclophosphamide administered mice POF. The impact follicles sex hormones evaluated through HE staining ELISA,...
We observed the effect of body mass index (BMI) on pregnancy outcomes in Chinese patients undergoing assisted reproductive treatment (ART). All were divided into polycystic ovary syndrome (PCOS) group and non-PCOS group, then according to BMI, each was subdivided 6 subgroups: 1 (BMI < 18 kg/m2), 2 (18-20 3 (20-22 4 (22-24 5 (24-26 kg/m2) > 26.0 kg/m2). found that 20 25-year-old patients, rate not significantly correlated with BMI PCOS patients; while non-POCS decreased at cut-off point value...
Dyszoospermia due to genetic factors is the leading cause of male infertility.To explore correlation between azoospermia factor (AZF) microdeletion Y chromosome and infertility, we evaluated AZF on long arm in 166 infertile males 50 fertile using multiplex polymerase chain reactions amplification gel electrophoresis.The results demonstrated that 28 individuals had varying degrees region (16.90%); 12 out 76 with 16 90 oligospermia microdeletion.AZF was not observed any healthy controls.In...
This study aimed to explore the association between soluble receptor for advanced glycation end products (sRAGE) levels in follicular fluid and number of oocytes retrieved evaluate effect sRAGE on vascular endothelial growth factor (VEGF) granulosa cells patients with polycystic ovarian syndrome (PCOS). Two sets experiments were performed this study. In part one, VEGF protein samples from 39 PCOS 35 non-PCOS measured by ELISA. two, isolated an additional 10 cultured. SP1 mRNA levels, as well...
Abstract Background In recent years, some studies have shown that there is a positive association between the number of oocytes retrieved and cumulative live birth rate (CLBR) after fresh frozen cycles one oocyte retrieval. However, almost no examined CLBR when using “freeze-all” strategy. We performed this study to investigate effects an extreme yield during first cycle on among patients younger than 35 years old. Methods This was retrospective cohort in university-affiliated reproductive...