The optical response of plasmonic nanogaps is challenging to address when the separation between two nanoparticles forming gap reduced a few nanometers or even subnanometer distances. We have compared results plasmon within different levels approximation, and identified classical local regime, nonlocal regime quantum interaction. For separations Ångstroms, in tunneling can occur, strongly modifying optics nanogap. considered effective model, so called Quantum Corrected Model (QCM), that has...

We present an ab initio study of the hybridization localized surface plasmons in a metal nanoparticle dimer. The atomic structure, which is often neglected theoretical studies quantum nanoplasmonics, has strong impact on optical absorption properties when subnanometric gaps between nanoparticles are considered. demonstrate that this influences resonances dimer, and leads to significantly smaller electric field enhancements as compared standard jellium model. In addition, we show corrugation...

Semiclassical nonlocal optics based on the hydrodynamic description of conduction electrons might be an adequate tool to study complex phenomena in emerging field nanoplasmonics. With aim confirming this idea, we obtain local and optical absorption spectra a model nanoplasmonic device which there are spatial gaps between components at nanometric subnanometric scales. After comparison against time-dependent density functional calculations, conclude that provides exhibiting qualitative...

Abstract Mode and polarization‐division multiplexing technologies (MDM PDM) can offer considerable parallelism for optical biosensors, complex neural networks, high‐capacity interconnects, while requiring only a single‐wavelength laser source. Thanks to the mature fabrication processes of silicon nitride superior material properties lithium niobate, loaded niobate on insulator (LNOI) platform allows integration high‐speed modulators (de)multiplexing devices achieve low‐cost photonic...

Electro-optic (EO) modulators, which convert signals from the electrical to optical domain plays a key role in modern communication systems. Lithium niobate on insulator (LNOI) technology has emerged as competitive solution realize high-performance integrated EO modulators. In this Letter, we design and experimentally demonstrate Mach-Zehnder interferometer-based modulator silicon nitride loaded LNOI platform, not only takes full advantage of excellent effect LiNbO3, but also avoids direct...

The self-assembly of two-dimensional (2D) graphene sheets into three-dimensional (3D) structures is an effective approach to fabricate graphene-based hierarchical architectures for practical applications. Here we report easy and environmentally friendly method a multifunctional hydrogel using biocompatible polysaccharide as both stabilizer physical cross-linking agent. as-prepared highly stable in variety harsh conditions such strong acid, alkali, high ion strength solution, organic solvent....

Dielectrically loaded thin-film lithium niobate (LiNbO3) on insulator (LNOI) platforms have enabled a range of photonic integrated circuit components, such as high-speed optical modulators, switches, and nonlinear devices, while avoiding the direct etching LiNbO3 thin film. Silicon nitride (Si3N4) is one most attractive dielectric loading materials it has similar refractive index transparency window to can be deposited patterned by mature fabrication processes. The patterning Si3N4 opens...

Background Some VOCs are identified as endocrine-disrupting chemicals (EDCs), interfering with the effect of sex hormones. However, no studies focused on common spectrum environmental exposure affecting hormones in average male population. Objectives We aimed to explore association between and American adult males using multiple statistical models. Methods The generalized linear (GLM), eXtreme Gradient Boosting (XGBoost), weighted quantile sum (WQS), Bayesian kernel machine regression (BKMR)...

Extracellular matrix (ECM) accumulation in liver fibrosis is caused by the activation of hepatic stellate cells (HSCs).The goal this study was to develop a 99m Tc-labeled N-acetylglucosamine (GlcNAc) that specifically interacts with desmin and vimentin expressed on activated HSCs monitor progression prognosis using single-photon emission computed tomography (SPECT) imaging.Methods: GlcNAc-conjugated polyethylenimine (PEI) first prepared radiolabeled Tc.Noninvasive SPECT imaging Tc-GlcNAc-PEI...

Plasmonic gap structures are among the few configurations capable of generating extreme light confinement, finding applications in surface-enhanced spectroscopy, ultrasensitive detection, photocatalysis, and more. Their plasmonic response undergoes a dramatic, quantum effect-driven transition as size approaches zero. Modal analysis can reveal insights into mechanisms governing this process, which otherwise obscured by nonlocal damping effects. Here, we offer fresh modal perspective on using...

Estimations of blood flow shear stress and its distribution have great importance for preventing carotid artery stenosis predicting plaque stability. Physics-informed neural network (PINN) can utilize less data points with unknown boundary conditions obtain high-resolution accurate solutions under the constraints physical equations. This makes PINN well-suited to address clinical hemodynamic modeling problems. However, basic structure might cause an imbalance among loss function terms is...

We present a transformation-optics approach which sheds analytical insight into the impact that spatial dispersion has on optical response of separated dimers metallic nanowires. show nonlocal effects are apparent at interparticle distances one order magnitude larger than longitudinal plasmon decay length, coincides with regime where electron tunneling phenomena occur. Our method also clarifies interplay between and radiation taking place in nanostructure, yielding dimer dimensions optimize...

Lithium niobate on insulator (LNOI) has been demonstrated as a promising platform for photonic integrated circuits (PICs), thanks to its excellent properties such strong electro‐optic effect, low material loss, and wide transparency window. Herein, monolithic PIC high‐speed data communication application lithium‐niobate‐etchless with silicon nitride (Si 3 N 4 ) loading is proposed demonstrated. The fabricated consists of four racetrack resonator modulators pair four‐channel mode...

Mode-division-multiplexing technology is highly attractive to increase the capacity of optical interconnects. Various multimode operations have been investigated, among which mode switches provide one most important functions in mode-division-multiplexing systems. However, current a non-negligible switching time, can lead an undesired cumulative delay network. In this contribution, we propose and experimentally demonstrate switch using three-waveguide-coupling structure lithium niobate on...

Abstract Erdafitinib is a novel fibroblast growth factor receptor (FGFR) inhibitor that has shown great therapeutic promise for solid tumor patients with FGFR3 alterations, especially in urothelial carcinoma. However, the mechanisms of resistance to FGFR inhibitors remain poorly understood. In this study, we found could kill cells by inducing incomplete autophagy and increasing intracellular reactive oxygen species levels. We have established an Erdafitinib‐resistant cell line, RT‐112‐RS....

Concentrating optical field in an eigenmode with a tiny volume is vitally important for light-matter interactions at the fundamental level and underpins new technologies. In past decades, researchers have investigated various approaches to shrink light so far managed reduce of eigenmodes, under quantum-optical definition, down several ten nm3. Here we report on discovery, characterization engineering class extremely localized eigenmodes that are resonances atomistic protrusions metallic host...

A recursive image charge approach has been successfully developed for quantitative microwave microscopy of dielectric thin films using the scanning evanescent microscope. With this and recursion-to-circulation algorithm, frequency shift microscope as functions thickness film, constants film substrate can be efficiently computed in a circulation way.

An electromagnetic energy squeezing mechanism is proposed based on the special properties of permeability-near-zero metamaterials. It found that nearly no stream can enter a simply connected conventional dielectric material positioned inside material. When domain shaped as split ring (with gap opened) surrounding source, generated by source forced to propagate through gap. narrow, density becomes very large and makes magnetic field enhanced drastically in The narrow be long bended. This...

We review some recent approaches to transmission enhancement and light harvesting based on optical nano-antennas metamaterials. Nano-cavity antennas are used enhance the extraordinary of TM-polarized through vertical nano-slits in a metal film. The enhanced TE-polarized waves an array subwavelength-slits thin film at low frequencies (including microwave) is also investigated. Light with metamaterial cloaking shell demonstrated.

Abstract Background The dreadful prognosis of nonmuscle invasive bladder cancer mainly results from the delay in recognition individuals with a high risk progression. Thus, emphasis this work lies developing valuable biomarkers that is conducive to accurately predicting progression NMIBC. Methods Microarray data GSE32894 including 209 NMIBC samples were performed by weighted gene coexpression network analysis (WGCNA), which could find modules highly correlated genes and relate external...

Fluidic memristor devices have received tremendous attention for smooth resistance switching in artificial synapses due to the ion migration, concentration polarization, and redox reactions mechanism. Here we provide a novel method of preparing microfluidic with superior stability, robustness, ultralow cost. The structure two-terminal device is Cu/[MMIm][Cl]: H2O/Cu, C5H9N2Cl. ionic liquid 1,3-dimethylimidazole chloride salt was used as representative IL display resistive memory properties...

Abstract We demonstrate an all-polarization-maintaining (PM) ytterbium (Yb)-doped fiber laser with a figure-of-9 structure to generate mode-locked pulses high single pulse energy and repetition frequency. By exploiting the nonlinear amplifying loop mirror, stably self-started mode-locking is achieved spectrum bandwidth of 13 nm duration 4.53 ps. The fundamental frequency 97.966 MHz at maximum output power 143 mW in operation, corresponding 1.46 nJ. maintain both single-pulse energy. This...

Hydropower is a significant component of China’s contemporary energy framework, with its construction and operation critically contributing to the advancement sustainable development in region. However, influence hydropower on regional not evident, course effect clear. In this work, basis assessing development, system dynamics (SD) simulation model was created, 15 distinct modes were set tested. The relative driving efficiency growth province Southwest China under several scenarios assessed...

A new scheme is suggested to manipulate the probe transitions (and hence optical properties of atomic vapors) via double-control destructive and constructive quantum interferences. The influence phase coherence between two control on transition also studied. most remarkable feature present that (absorption, transparency dispersion) an system can be manipulated using this multi-pathway interferences (multiple routes excitation). It shown a four-level will exhibit two-level resonant absorption...

A general method is proposed to construct an approximate nonsingular two-dimensional (2D) cloak by taking constitutive parameter tensors (CPTs) of a three-dimensional perfect on mirror-symmetric cross section in order avoid any singularity at the inner boundary 2D cloak. As two examples, reduced models for elliptic and bow-tie are derived. The characterized explicitly with CPT finite values good cloaking effects verified numerically.