- SARS-CoV-2 and COVID-19 Research
- Animal Virus Infections Studies
- COVID-19 epidemiological studies
- Viral Infections and Outbreaks Research
- Viral gastroenteritis research and epidemiology
- Mosquito-borne diseases and control
- Taxation and Compliance Studies
- Hernia repair and management
- Child and Adolescent Psychosocial and Emotional Development
- Vaccine Coverage and Hesitancy
- Embedded Systems Design Techniques
- Abdominal Surgery and Complications
- CCD and CMOS Imaging Sensors
- Infection Control and Ventilation
- Financial Literacy, Pension, Retirement Analysis
- Child Nutrition and Feeding Issues
- Chromosomal and Genetic Variations
- Analog and Mixed-Signal Circuit Design
- Air Quality Monitoring and Forecasting
- Diverticular Disease and Complications
- Atmospheric and Environmental Gas Dynamics
- Monoclonal and Polyclonal Antibodies Research
- Air Quality and Health Impacts
- CRISPR and Genetic Engineering
- Maternal Mental Health During Pregnancy and Postpartum
Translational Health Science and Technology Institute
2021-2024
Abstract Immunization is expected to confer protection against infection and severe disease for vaccines while reducing risks unimmunized populations by inhibiting transmission. Here, based on serial serological studies of an observational cohort healthcare workers, we show that during a Severe Acute Respiratory Syndrome -Coronavirus 2 Delta-variant outbreak in Delhi, 25.3% (95% Confidence Interval 16.9-35.2) previously uninfected, ChAdOx1-nCoV19 double vaccinated, workers were infected...
Abstract Recent advances in vaccine technology have positioned messenger RNA (mRNA) vaccines as safe and reliable options for human use. Conventionally, mRNA were designed using linear or self-amplifying (SAM), the latter considered to be superior. However, limited success was achieved with SAM during COVID-19 pandemic. Further, studies on Circular (Circ-RNA) against SARS-CoV-2, Ebola monkey pox proved their efficacy. Circ-RNAs are highly stable, neither they induce inflammatory response nor...
Dengue disease is highly prevalent in tropical and subtropical regions worldwide. However, its pathogenesis still incompletely understood, particularly comparison to other endemic viruses. Antibody-dependent enhancement (ADE) a well-known phenomenon for dengue Given the recent surge cases potential cross-reactivity with SARS-CoV-2 antibodies, this study explores impact of anti-SARS-CoV-2 antibodies on DENV-2 infection. The assessed Virus. Human convalescent plasma samples collected during...
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Abstract The presence of non-neutralizing antibodies any dengue serotype, increase the severity subsequent infection by other serotypes. During SARS-CoV-2 pandemic, number symptomatic cases increased in India. cross-reactivity with is well reported. We investigated potential spike to modulate infection. In-silico and In-vitro studies revealed protein-protein interactions between envelope protein. Convalescent plasma from COVID-19 patients monoclonal/polyclonal showed impact on cell-based...
Abstract Immunization is expected to confer protection against infection and severe disease for vaccinees, while reducing risks unimmunized populations by inhibiting transmission. Here, based on serial serological studies, we show that during a SARS-CoV2 Delta-variant outbreak in Delhi, 25.3% (95% CI 16.9 - 35.2) of previously uninfected, ChAdOx1-nCoV19 double vaccinated, healthcare-workers (HCW) were infected within period less than two months, serology. Induction anti-spike response was...
ABSTRACT
 
 Background: Anxiety disorders remain the commonest mental disorder in general population. Both these are common pregnant women and postpartum period underdiagnosed. There is a paucity of research on their risk factors among during postnatal India. This study aims to estimate incidence generalised anxiety (GAD) depression explore associated India.
 Aim: The present mothers attending outpatient department clinic (OPD) for vaccination children or gynaecology OPD...